Results 91 to 100 of about 282,753 (347)

Confirmation of quantitative trait loci affecting fatness in chickens

Genetics Selection Evolution, 2005
In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27.
Poel Jan, Crooijmans Richard MPA, Vereijken Addie LJ, Bovenhuis Henk, Jennen Danyel GJ, Groenen Martien AM   +5 more
doaj   +1 more source

IRF8 Drives Conventional Type 1 Dendritic Cell Differentiation and CD8+ T Cell Activation to Aggravate Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan, Li Shu, Yidan Zheng, Yidong Wang, Mengsha Zheng, Jie Sun, Jiantao Fu, Zihao Zhou, Shen Song, Zhenjie Liu, Fei Li, Zhejun Cai   +11 more
wiley   +1 more source

Breeding and selection of taro (Colocasia esculenta) for improved disease‐resistance in Hawaiʻi

PLANTS, PEOPLE, PLANET, Volume 5, Issue 1, Page 123-145, January 2023., 2023
Taro is a root crop with wide geographic range and high cultural significance to Indigenous peoples of Hawaiʻi and the Pacific. Taro Leaf Blight (TLB) is a worldwide disease of taro, and Hawaiian taro varieties exhibited little resistance to it. To improve TLB‐resistance, conventional breeding was conducted by hand‐pollination.
Roshan Paudel, Bjarne Bartlett, Carter M. Zamora, James E. Keach, Rosemary Gutierrez‐Coarite, Jennifer Hawkins, Amjad Ahmad, Sharon Motomura‐Wages, Emilie R. Kirk, Michael B. Kantar, Kurt H. Lamour, Christopher Bernabe, Michael Shintaku, Susan C. Miyasaka   +13 more
wiley   +1 more source

Rare variants contribute disproportionately to quantitative trait variation in yeast. [PDF]

, 2019
How variants with different frequencies contribute to trait variation is a central question in genetics. We use a unique model system to disentangle the contributions of common and rare variants to quantitative traits.
Bloom, Joshua S, Boocock, James, Day, Laura, Kruglyak, Leonid, Oates-Barker, Holly, Sadhu, Meru J, Treusch, Sebastian   +6 more
core   +1 more source

Complex-trait analysis in plants [PDF]

, 2010
Identifying quantitative trait loci in Arabidopsis by population and pedigree ...
Mitchell-Olds, Thomas
core   +2 more sources

Nanoparticle Delivery of Antisense miR162 Inhibits Invasive Habitat Adaption of Alternanthera Philoxeroides

Advanced Science, EarlyView.
This study demonstrates that the miRNA pathway plays a key role in the invasive growth of Alternanthera philoxeroides in aquatic habitats. Specifically, miR162 is critical for its invasive success, facilitating stem elongation and enhancing survival during submergence.
Qianqian Hu, Erfeng Kou, Xiuzhen Liao, Ruiyi Qiu, Qi Tang, Huan Zhang, Yun Zheng, Ji Yang, Binglian Zheng   +8 more
wiley   +1 more source

Discovery of loci determining pre-harvest sprouting and dormancy in wheat and barley applying segregation and association mapping

Biologia Plantarum, 2013
Three wheat and two barley populations were studied in order to find loci responsible for dormancy and pre-harvest sprouting. A classical quantitative trait loci analysis was combined with an association mapping approach. Many quantitative trait loci and
U. Lohwasser, M. A. Rehman Arif, A. Börner   +2 more
doaj   +1 more source

Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart

PLoS ONE, 2014
In recent years genome-wide association studies (GWAS) have uncovered numerous chromosomal loci associated with various electrocardiographic traits and cardiac arrhythmia predisposition.
T. Koopmann, M. Adriaens, P. Moerland, R. Marsman, M. L. Westerveld, S. Lal, Taifang Zhang, Christine Q. Simmons, I. Baczkó, C. D. dos Remedios, N. Bishopric, A. Varró, A. George, Elisabeth M. Lodder, C. Bezzina   +14 more
semanticscholar   +1 more source

Wnt Inhibition Safeguards Porcine Embryonic Stem Cells From the Acquisition of Extraembryonic Endoderm Cell Fates

Advanced Science, EarlyView.
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang, Liang Zhong, Zhuangfei Wang, Jinzhu Xiang, Duanqing Pei   +4 more
wiley   +1 more source

Multipoint quantitative-trait linkage analysis in general pedigrees.

American Journal of Human Genetics, 1998
Multipoint linkage analysis of quantitative-trait loci (QTLs) has previously been restricted to sibships and small pedigrees. In this article, we show how variance-component linkage methods can be used in pedigrees of arbitrary size and complexity, and ...
L. Almasy, J. Blangero
semanticscholar   +1 more source