Results 31 to 40 of about 313,777 (344)
Nature Genetics, 2018 There is increasing evidence that many risk loci found using genome-wide association studies are molecular quantitative trait loci (QTLs). Here we introduce a new set of functional annotations based on causal posterior probabilities of fine-mapped ...
F. Hormozdiari +12 more
semanticscholar +1 more source
The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]
, 2018 Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S +2 more
core +1 more source
Unraveling the Genetic Architecture of Complex Traits in Plants
Acta Biológica Colombiana, 2023 Complex traits are those whose inheritance does not follow simple and predictable patterns. They are not governed by a single locus, instead, they are determined by several loci and are influenced by the environment.
Laura Vanessa Chivatá-Peña +2 more
doaj +1 more source
Plant, Cell and Environment, 2018 The increasing salinization of agricultural lands is a threat to global wheat production. Understanding of the mechanistic basis of salt tolerance (ST) is essential for developing breeding and selection strategies that would allow for increased wheat ...
B. C. Oyiga +5 more
semanticscholar +1 more source
A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains. [PDF]
, 2015 The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions.
Andersen, Erik C +7 more
core +2 more sources
Nucleic Acids Research, 2018 Quantitative trait locus (QTL) mapping of molecular phenotypes such as metabolites, lipids and proteins through genome-wide association studies represents a powerful means of highlighting molecular mechanisms relevant to human diseases.
D. Stacey +8 more
semanticscholar +1 more source
Frontiers in Plant Science, 2019 Enhanced grain yield has been achieved in bread wheat (Triticum aestivum L.) through development and cultivation of superior genotypes incorporating yield-related agronomic and physiological traits derived from genetically diverse and complementary ...
Nkhathutsheleni Maureen Tshikunde +3 more
semanticscholar +1 more source
Genetic regulation of cholesterol absorption and plasma plant sterol levels
Journal of Lipid Research, 2003 The molecular basis of the processes that control two closely related traits, the absorption of cholesterol from the intestines and plasma plant sterol levels, are only partially understood. The discovery that mutations in two novel hemitransporters, ATP
Ephraim Sehayek
doaj +1 more source
Tropical Agricultural Research, 2018 Root architectural traits are governed by many genes exhibiting polygenic inheritance. The dissection of the genetic basis of root traits could be achieved by mapping of quantitative trait loci (QTLs) using molecular markers.
D. R. Gimhani +3 more
doaj +1 more source
HGG AdvancesSummary: We designed a massively parallel reporter assay (MPRA) in an Epstein-Barr virus transformed B cell line to directly characterize the potential for histone post-translational modifications, i.e., histone quantitative trait loci (hQTLs ...
Yao Fu +8 more
doaj +1 more source