Results 31 to 40 of about 308,676 (247)
Unraveling the Genetic Architecture of Complex Traits in Plants
Acta Biológica Colombiana, 2023 Complex traits are those whose inheritance does not follow simple and predictable patterns. They are not governed by a single locus, instead, they are determined by several loci and are influenced by the environment.
Laura Vanessa Chivatá-Peña +2 more
doaj +1 more source
Multiple locus linkage analysis of genomewide expression in yeast. [PDF]
, 2005 With the ability to measure thousands of related phenotypes from a single biological sample, it is now feasible to genetically dissect systems-level biological phenomena.
Akey, Joshua M +2 more
core +4 more sources
Nature Genetics, 2018 There is increasing evidence that many risk loci found using genome-wide association studies are molecular quantitative trait loci (QTLs). Here we introduce a new set of functional annotations based on causal posterior probabilities of fine-mapped ...
F. Hormozdiari +12 more
semanticscholar +1 more source
A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains. [PDF]
, 2015 The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions.
Andersen, Erik C +7 more
core +2 more sources
Genome Biology, 2018 Genetic influences on gene expression in the human fetal brain plausibly impact upon a variety of postnatal brain-related traits, including susceptibility to neuropsychiatric disorders. However, to date, there have been no studies that have mapped genome-
Heath E. O’Brien +14 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2022 An enormous challenge in the post-genome era is to annotate and resolve the consequences of genetic variation on diverse phenotypes. The genome-wide association study (GWAS) is a well-known method to identify potential genetic loci for complex traits ...
Kai Yuan +7 more
doaj +1 more source
Genetic regulation of cholesterol absorption and plasma plant sterol levels
Journal of Lipid Research, 2003 The molecular basis of the processes that control two closely related traits, the absorption of cholesterol from the intestines and plasma plant sterol levels, are only partially understood. The discovery that mutations in two novel hemitransporters, ATP
Ephraim Sehayek
doaj +1 more source
Nucleic Acids Research, 2018 Quantitative trait locus (QTL) mapping of molecular phenotypes such as metabolites, lipids and proteins through genome-wide association studies represents a powerful means of highlighting molecular mechanisms relevant to human diseases.
D. Stacey +8 more
semanticscholar +1 more source
Tropical Agricultural Research, 2018 Root architectural traits are governed by many genes exhibiting polygenic inheritance. The dissection of the genetic basis of root traits could be achieved by mapping of quantitative trait loci (QTLs) using molecular markers.
D. R. Gimhani +3 more
doaj +1 more source
Prioritizing quantitative trait loci for root system architecture in tetraploid wheat
Journal of Experimental Botany, 2016 Optimization of root system architecture (RSA) traits is an important objective for modern wheat breeding. Linkage and association mapping for RSA in two recombinant inbred line populations and one association mapping panel of 183 elite durum wheat ...
M. Maccaferri +7 more
semanticscholar +1 more source