Results 41 to 50 of about 308,676 (247)

Massively parallel reporter assay confirms regulatory potential of hQTLs and reveals important variants in lupus and other autoimmune diseases

HGG Advances
Summary: We designed a massively parallel reporter assay (MPRA) in an Epstein-Barr virus transformed B cell line to directly characterize the potential for histone post-translational modifications, i.e., histone quantitative trait loci (hQTLs ...
Yao Fu, Jennifer A. Kelly, Jaanam Gopalakrishnan, Richard C. Pelikan, Kandice L. Tessneer, Satish Pasula, Kiely Grundahl, David A. Murphy, Patrick M. Gaffney   +8 more
doaj   +1 more source

Construction of a high-density genetic map by specific locus amplified fragment sequencing (SLAF-seq) and its application to Quantitative Trait Loci (QTL) analysis for boll weight in upland cotton (Gossypium hirsutum.)

BMC Plant Biology, 2016
Upland Cotton (Gossypium hirsutum) is one of the most important worldwide crops it provides natural high-quality fiber for the industrial production and everyday use.
Zhen Zhang, Haihong Shang, Yuzhen Shi, Long Huang, Jun-wen Li, Qun Ge, Juwu Gōng, Ai-ying Liu, Tingting Chen, Dan Wang, Yanling Wang, Koffi Kibalou Palanga, Jamshed Muhammad, Weijie Li, Quanwei Lu, Xiaoying Deng, Yunna Tan, Weiwu Song, Juan Cai, Peng-tao Li, H. Rashid, Wànkuí Gǒng, You-lu Yuan   +22 more
semanticscholar   +1 more source

Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice

Journal of Lipid Research, 2011
To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analysis between inbred mouse strains MRL/MpJ and SM/J, measuring triglyceride levels at 8 weeks of age in F2 mice fed a chow diet.
Magalie S. Leduc, Rachael S. Hageman, Ricardo A. Verdugo, Shirng-Wern Tsaih, Kenneth Walsh, Gary A. Churchill, Beverly Paigen   +6 more
doaj   +1 more source

Agronomic and Physiological Traits, and Associated Quantitative Trait Loci (QTL) Affecting Yield Response in Wheat (Triticum aestivum L.): A Review

Frontiers in Plant Science, 2019
Enhanced grain yield has been achieved in bread wheat (Triticum aestivum L.) through development and cultivation of superior genotypes incorporating yield-related agronomic and physiological traits derived from genetically diverse and complementary ...
Nkhathutsheleni Maureen Tshikunde, J. Mashilo, H. Shimelis, A. Odindo   +3 more
semanticscholar   +1 more source

Linkage disequilibrium interval mapping of quantitative trait loci

BMC Genomics, 2006
Background For many years gene mapping studies have been performed through linkage analyses based on pedigree data. Recently, linkage disequilibrium methods based on unrelated individuals have been advocated as powerful tools to refine estimates of gene ...
de Rochambeau Hubert, Abdallah Jihad, Boitard Simon, Cierco-Ayrolles Christine, Mangin Brigitte   +4 more
doaj   +1 more source

Expression quantitative trait loci associated with Nellore meat pH. [PDF]

, 2023
Genomic studies make it possible to identify polymorphisms associated with quantitative characteristics of economic interest, such as meat pH, a factor that influences meat ...
BEATRIZ, D. L., COUTINHO, L. L., GARCIA, I. S., REGITANO, L. C. de A., SILVA, T. R. da, SILVA-VIGNATO, B.   +5 more
core  

Expression quantitative trait loci analysis in plants [PDF]

, 2010
An expression Quantitative Trait Locus or eQTL is a chromosomal region that accounts for a proportion of the variation in abundance of a mRNA transcript observed between individuals in a genetic mapping population.
Chen, Xinwei, Druka, Arnis, Jiang, Ning, Kearsey, Mike, Luo, Zewei, Potokina, Elena, Waugh, Robbie   +6 more
core   +2 more sources

CHROMOSOME LOCATION OF GENETIC FACTORS DETERMINIG PHYSIOLOGICAL AND BIOCHEMICAL PROCESSES ASSOCIATED WITH DROUGHT TOLERANCE IN WHEAT TRITICUM AESTIVUM L. [PDF]

Journal of Stress Physiology & Biochemistry, 2012
Drought tolerance is characterized as the most recalcitrant trait to improve for its complexity and considered target for genomic-assisted improvement. A profitable genetic strategy lies in the discovery and exploitation of quantitative trait loci (QTL ...
Osipova S., M. Permyakova, A. Permyakov, T. Pshenichnikova, A. Börner, V. Verkhoturov   +5 more
doaj  

A Latent Variable Approach to Multivariate Quantitative Trait Loci [PDF]

, 2010
A novel approach based on latent variable modelling is presented for the analysis of multivariate quantitative and qualitative trait loci. The approach is general in the sense that it enables the joint analysis of many kinds of quantitative and ...
Bob O', Mikko J. Sillanpä, Outi Savolainen, Pä   +3 more
core   +1 more source

Methylation quantitative trait loci in the developing brain and their enrichment in schizophrenia-associated genomic regions

Nature Neuroscience, 2015
We characterized DNA methylation quantitative trait loci (mQTLs) in a large collection (n = 166) of human fetal brain samples spanning 56–166 d post-conception, identifying >16,000 fetal brain mQTLs.
E. Hannon, H. Spiers, Joana Viana, R. Pidsley, Joe Burrage, Therese M. Murphy, C. Troakes, G. Turecki, M. O’Donovan, L. Schalkwyk, N. Bray, J. Mill   +11 more
semanticscholar   +1 more source