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Evolution Letters, Volume 6, Issue 6, Page 460-473, December 2022., 2022 Abstract Plants have evolved diverse reproductive allocation strategies and seed traits to aid in dispersal, persistence in the seed bank, and establishment. In particular, seed size, dormancy, and early seedling vigor are thought to be key functional traits with important recruitment and fitness consequences across abiotic stress gradients.
Samsad Razzaque, Thomas E. Juenger
wiley +1 more source
Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast. [PDF]
, 2016 Experiments in model organisms report abundant genetic interactions underlying biologically important traits, whereas quantitative genetics theory predicts, and data support, the notion that most genetic variance in populations is additive.
Bloom, Joshua S +4 more
core +3 more sources
MAPfastR: Quantitative Trait Loci Mapping in Outbred Line Crosses [PDF]
, 2013 MAPfastR is a software package developed to analyze quantitative trait loci data from inbred and outbred line-crosses. The package includes a number of modules for fast and accurate quantitative trait loci analyses.
Alvarez-Castro, J. M. +12 more
core +1 more source
Hepatology, EarlyView., 2022 KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou +15 more
wiley +1 more source
Population differences in transcript-regulator expression quantitative trait loci.
PLoS ONE, 2012 Gene expression quantitative trait loci (eQTL) are useful for identifying single nucleotide polymorphisms (SNPs) associated with diseases. At times, a genetic variant may be associated with a master regulator involved in the manifestation of a disease ...
Pierre R Bushel +7 more
doaj +1 more source
EXPLoRA-web: linkage analysis of quantitative trait loci using bulk segregant analysis [PDF]
, 2016 Identification of genomic regions associated with a phenotype of interest is a fundamental step toward solving questions in biology and improving industrial research.
Duitama, Jorge +2 more
core +3 more sources
The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]
, 2018 Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S +2 more
core +1 more source
The next 10 years of behavioural genomic research
JCPP Advances, Volume 2, Issue 4, December 2022., 2022 Three transformative developments for behavioural genomic research in the next 10 years are described. First, behavioural genomic research will use dimensional measures to reveal the hierarchical genetic architecture of psychopathology. A second direction for behavioural genomic research will be to investigate causa models of GE interplay.
Robert Plomin
wiley +1 more source
Nature Neuroscience, 2015 We characterized DNA methylation quantitative trait loci (mQTLs) in a large collection (n = 166) of human fetal brain samples spanning 56–166 d post-conception, identifying >16,000 fetal brain mQTLs.
E. Hannon +11 more
semanticscholar +1 more source
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 340, Issue 1, Page 8-17, January 2023., 2023 Experimental tests of theories about evolvability have largely been limited to examining the mechanisms by which genetic variation is produced; namely, mutation, and recombination. However, evolvability theory has a much broader domain, and opportunities abound to test ideas about developmental variability, environmental heterogeneity, and the ...
Jeremy A. Draghi, C. Brandon Ogbunugafor
wiley +1 more source