Results 61 to 70 of about 282,753 (347)

CHROMOSOME LOCATION OF GENETIC FACTORS DETERMINIG PHYSIOLOGICAL AND BIOCHEMICAL PROCESSES ASSOCIATED WITH DROUGHT TOLERANCE IN WHEAT TRITICUM AESTIVUM L. [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2012
Drought tolerance is characterized as the most recalcitrant trait to improve for its complexity and considered target for genomic-assisted improvement. A profitable genetic strategy lies in the discovery and exploitation of quantitative trait loci (QTL ...
Osipova S.   +5 more
doaj  

SCFD1 expression quantitative trait loci in amyotrophic lateral sclerosis are differentially expressed [PDF]

open access: yes, 2021
Evidence indicates that common variants found in genome-wide association studies increase risk of disease through gene regulation via expression Quantitative Trait Loci.
UK Brain Expression Consortium
core  

Molecular genetic dissection of quantitative trait loci regulating rice grain size.

open access: yesAnnual Review of Genetics, 2014
Grain size is one of the most important factors determining rice yield. As a quantitative trait, grain size is predominantly and tightly controlled by genetic factors. Several quantitative trait loci (QTLs) for grain size have been molecularly identified
Jianru Zuo, Jiayang Li
semanticscholar   +1 more source

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

open access: yesAdvanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang   +6 more
wiley   +1 more source

Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci

open access: yesMolecular Autism, 2012
Background Autism spectrum disorder is a severe early onset neurodevelopmental disorder with high heritability but significant heterogeneity. Traditional genome-wide approaches to test for an association of common variants with autism susceptibility risk
Davis Lea K   +7 more
doaj   +1 more source

Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast

open access: yeseLife, 2022
Mapping the genetic basis of complex traits is critical to uncovering the biological mechanisms that underlie disease and other phenotypes. Genome-wide association studies (GWAS) in humans and quantitative trait locus (QTL) mapping in model organisms can
Alex N Nguyen Ba   +6 more
doaj   +1 more source

Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1993
It is now possible to use complete genetic linkage maps to locate major quantitative trait loci (QTLs) on chromosome regions. The current methods of QTL mapping (e.g., interval mapping, which uses a pair or two pairs of flanking markers at a time for ...
Z. Zeng
semanticscholar   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

open access: yesAdvanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li   +3 more
wiley   +1 more source

Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]

open access: yes, 2004
Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K.   +4 more
core   +1 more source

Rice and cold stress: methods for its evaluation and summary of cold tolerance-related quantitative trait loci

open access: yesRice, 2014
Cold stress adversely affects rice (Oryza sativa L.) growth and productivity, and has so far determined its geographical distribution. Dissecting cold stress-mediated physiological changes and understanding their genetic causes will facilitate the ...
Qi Zhang   +4 more
semanticscholar   +1 more source

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