Results 61 to 70 of about 282,753 (347)
CHROMOSOME LOCATION OF GENETIC FACTORS DETERMINIG PHYSIOLOGICAL AND BIOCHEMICAL PROCESSES ASSOCIATED WITH DROUGHT TOLERANCE IN WHEAT TRITICUM AESTIVUM L. [PDF]
Drought tolerance is characterized as the most recalcitrant trait to improve for its complexity and considered target for genomic-assisted improvement. A profitable genetic strategy lies in the discovery and exploitation of quantitative trait loci (QTL ...
Osipova S.+5 more
doaj
SCFD1 expression quantitative trait loci in amyotrophic lateral sclerosis are differentially expressed [PDF]
Evidence indicates that common variants found in genome-wide association studies increase risk of disease through gene regulation via expression Quantitative Trait Loci.
UK Brain Expression Consortium
core
Molecular genetic dissection of quantitative trait loci regulating rice grain size.
Grain size is one of the most important factors determining rice yield. As a quantitative trait, grain size is predominantly and tightly controlled by genetic factors. Several quantitative trait loci (QTLs) for grain size have been molecularly identified
Jianru Zuo, Jiayang Li
semanticscholar +1 more source
A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang+6 more
wiley +1 more source
Background Autism spectrum disorder is a severe early onset neurodevelopmental disorder with high heritability but significant heterogeneity. Traditional genome-wide approaches to test for an association of common variants with autism susceptibility risk
Davis Lea K+7 more
doaj +1 more source
Mapping the genetic basis of complex traits is critical to uncovering the biological mechanisms that underlie disease and other phenotypes. Genome-wide association studies (GWAS) in humans and quantitative trait locus (QTL) mapping in model organisms can
Alex N Nguyen Ba+6 more
doaj +1 more source
Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci.
It is now possible to use complete genetic linkage maps to locate major quantitative trait loci (QTLs) on chromosome regions. The current methods of QTL mapping (e.g., interval mapping, which uses a pair or two pairs of flanking markers at a time for ...
Z. Zeng
semanticscholar +1 more source
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li+3 more
wiley +1 more source
Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]
Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K.+4 more
core +1 more source
Cold stress adversely affects rice (Oryza sativa L.) growth and productivity, and has so far determined its geographical distribution. Dissecting cold stress-mediated physiological changes and understanding their genetic causes will facilitate the ...
Qi Zhang+4 more
semanticscholar +1 more source