Results 81 to 90 of about 308,676 (247)

Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart

PLoS ONE, 2014
In recent years genome-wide association studies (GWAS) have uncovered numerous chromosomal loci associated with various electrocardiographic traits and cardiac arrhythmia predisposition.
T. Koopmann, M. Adriaens, P. Moerland, R. Marsman, M. L. Westerveld, S. Lal, Taifang Zhang, Christine Q. Simmons, I. Baczkó, C. D. dos Remedios, N. Bishopric, A. Varró, A. George, E. Lodder, C. Bezzina   +14 more
semanticscholar   +1 more source

Quantitative Trait Loci Identify Functional Noncoding Variation in Cancer.

PLoS Genetics, 2016
The interpretation of noncoding alterations in cancer genomes presents an unresolved problem in cancer studies. While the impact of somatic variations in protein-coding regions is widely accepted, noncoding aberrations are mostly considered as passenger ...
Holger Heyn
doaj   +1 more source

Targeted Methods for Finding Quantitative Trait Loci [PDF]

, 2011
Conventional genetic mapping methods typically assume parametric models with Gaussian errors, and obtain parameter estimates through maximum likelihood estimation.
Rose, Sherri, van der Laan, Mark J., Wang, Hui   +2 more
core   +1 more source

Quantitative trait loci for fertility traits in Finnish Ayrshire cattle [PDF]

, 2009
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Lund, Mogens S., Sahana, Goutam, Schulman, Nina F., Viitala, Sirja M., Vilkki, Johanna H.   +4 more
core   +1 more source

Mapping Quantitative Trait Loci onto Chromosome-Scale Pseudomolecules in Flax

Methods and Protocols, 2020
Quantitative trait loci (QTL) are genomic regions associated with phenotype variation of quantitative traits. To date, a total of 313 QTL for 31 quantitative traits have been reported in 14 studies on flax.
Frank M. You, Sylvie Cloutier
doaj   +1 more source

Heritability and tissue specificity of expression quantitative trait loci.

PLoS Genetics, 2006
Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene
Enrico Petretto, Jonathan Mangion, Nicholas J Dickens, Stuart A Cook, Mande K Kumaran, Han Lu, Judith Fischer, Henrike Maatz, Vladimir Kren, Michal Pravenec, Norbert Hubner, Timothy J Aitman   +11 more
doaj   +1 more source

Genome mapping of quantitative trait loci (QTL) controlling domestication traits of intermediate wheatgrass (Thinopyrum intermedium). [PDF]

, 2019
Allohexaploid (2n = 6x = 42) intermediate wheatgrass (Thinopyrum intermedium), abbreviated IWG, is an outcrossing perennial grass belonging to the tertiary gene pool of wheat.
Anderson, James, Crain, Jared, DeHaan, Lee, Dorn, Kevin, Grimwood, Jane, Jenkins, Jerry, Jensen, Kevin, Kantarski, Traci, Larson, Steve, Poland, Jesse, Robbins, Matthew, Schmutz, Jeremy, Shu, Shengqiang, Zhang, Xiaofei   +13 more
core  

Rice root genetic architecture: Meta-analysis from a drought QTL database [PDF]

, 2009
During the last 10 years, a large number of quantitative trait loci (QTLs) controlling rice root morphological parameters have been detected in several mapping populations by teams interested in improving drought resistance in rice.
Ahmadi, Nourollah, Courtois, Brigitte, Frouin, Julien, Hamelin, Chantal, Khowaja, Farhkanda S., Price, Adam H., Rami, Jean-François, Ruiz, Manuel   +7 more
core   +1 more source

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

PLoS Genetics, 2010
A fundamental challenge in the post-genome era is to understand and annotate the consequences of genetic variation, particularly within the context of human tissues.
J. Gibbs, Marcel P. van der Brug, D. Hernandez, B. Traynor, M. Nalls, Shiao-lin Lai, S. Arepalli, Allissa Dillman, Ian Rafferty, J. Troncoso, Robert Johnson, H. Zielke, L. Ferrucci, D. Longo, M. Cookson, A. Singleton   +15 more
semanticscholar   +1 more source

Confirmation of quantitative trait loci affecting fatness in chickens

Genetics Selection Evolution, 2005
In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27.
Poel Jan, Crooijmans Richard MPA, Vereijken Addie LJ, Bovenhuis Henk, Jennen Danyel GJ, Groenen Martien AM   +5 more
doaj   +1 more source