Results 181 to 190 of about 36,433 (262)

Identifying expression and DNA methylation biomarkers for lung adenocarcinoma risk in East Asia. [PDF]

J Natl Cancer Inst
Chen TY, Chien LH, Jiang SS, Choi J, Hung HH, Hsiao CF, Shi J, Blechter B, Breeze CE, Chang GC, Chen KY, Tsai YH, Su WC, Huang MS, Chen YM, Wen YF, Chen CY, Wang CL, Tsai FY, Chen HL, Hsieh WS, Lin HC, Wang LH, Chen CJ, Yang PC, Chen CY, Rothman N, Chanock SJ, Lan Q, Chang IS, Hsiung CA.   +30 more
europepmc   +1 more source

Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 2, Page 268-281, August 2026.
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding, Dylan Hamitouche, Simon Thebault, Patrick Kearns, Ahmed Abdelhak, Adil Harroud   +5 more
wiley   +1 more source

Stress-tolerance genes in rice: bridging gene discovery, functional validation, and breeding applications. [PDF]

Front Plant Sci
Nyasulu M, Medison RG, Mushtaq W, Mataka SN.   +3 more
europepmc   +1 more source

Causal association and mechanistic validation of the USP8‐DLK1 axis in osteoarthritis: A genetic meta‐analysis integrated with in vitro and in vivo investigations

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Abstract Background/Objective Osteoarthritis (OA) affects more than 500 million people globally and remains without effective disease‐modifying therapy, owing in part to an incomplete understanding of the molecular mechanisms driving chondrocyte degeneration.
Sayed Abdulla Jami, Md Ariful Haque, Ernest Dapaah, Vidmi Taolam Martin, Md Tofazzale Hosain   +4 more
wiley   +1 more source

Mapping Genetic Modifiers of Polyp Formation in <i>Smad4</i>-Deficient Juvenile Polyposis Using the Collaborative Cross Mouse Population. [PDF]

Cells
Zohud O, Midlej K, Lone IM, Nashef A, Abu-Elnaaj I, Iraqi FA.   +5 more
europepmc   +1 more source

Integrative multi‐omics analysis prioritizes DPEP1 as a genetically supported candidate associated with skin cancer risk

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Flowchart of the study design outlining target identification, validation, and subsequent functional and translational characterization. Abstract Background Skin cancer (SC) is among the most prevalent malignancies, yet causal circulating proteins and tractable therapeutic targets remain poorly defined.
Fan Shen, Yongkai Yu, Zongfeng Liao, Liye Mao, Qianyun Wang, Wanju Wang, Yuanhui Liu, Ling Li   +7 more
wiley   +1 more source

Expression Quantitative Trait loci (QTL) in tumor adjacent normal breast tissue and breast tumor tissue. [PDF]

PLoS One, 2017
Quiroz-Zárate A, Harshfield BJ, Hu R, Knoblauch N, Beck AH, Hankinson SE, Carey V, Tamimi RM, Hunter DJ, Quackenbush J, Hazra A.   +10 more
europepmc   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Maize Biofortification Approaches for Fighting Malnutrition in Sub‐Saharan Africa

Plant-Environment Interactions, Volume 7, Issue 4, August 2026.
ABSTRACT Maize is a staple food in sub‐Saharan Africa (SSA); however, commonly used maize varieties are deficient in essential nutrients, including lysine, tryptophan, vitamin A, and minerals such as iron (Fe) and zinc (Zn). As a result, millions of people in this region suffer from one or more nutrient deficiencies that commonly lead to malnutrition ...
Bitew Tilahun Engida, Tesfaye Walle Mekonnen, Maryke Labuschagne   +2 more
wiley   +1 more source

Linked genetic loci and genotype-dependent temperature effects shape craniofacial morphology in medaka. [PDF]

G3 (Bethesda)
Shinya M, Kimura T, Ikeda T, Nakamura R, Takeda H, Naruse K.   +5 more
europepmc   +1 more source