Results 31 to 40 of about 36,433 (262)

The Effects of Quantitative Trait Architecture on Detection Power in Short-Term Artificial Selection Experiments

G3: Genes, Genomes, Genetics, 2020
Evolve and resequence (E&R) experiments, in which artificial selection is imposed on organisms in a controlled environment, are becoming an increasingly accessible tool for studying the genetic basis of adaptation.
R. Nicolas Lou, Nina O. Therkildsen, Philipp W. Messer   +2 more
doaj   +1 more source

Genetic mapping of a pollinator preference trait: Nectar volume in sunflower (Helianthus annuus L.)

Frontiers in Plant Science, 2022
Although high pollinator visitation is crucial to ensure the yields of pollinator-dependent crops, the quantitative trait loci (QTL) controlling nectar volume in sunflower (Helianthus annuus L.), a pollinator preference trait, have yet to be identified ...
Ashley C. Barstow, Jarrad R. Prasifka, Ziv Attia, Nolan C. Kane, Brent S. Hulke   +4 more
doaj   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

Potential circadian rhythm-related pathogenic genes in diabetic nephropathy: a multi-omics Mendelian randomization study

Renal Failure
This study aims to identify pathogenic genes involved in diabetic nephropathy (DN) through multi-omics analysis of circadian rhythm disruptions to uncover targets for precision medicine.
Yanwen Mao, Minghao Zhang, Xiaojuan Li, Zijuan Zhang, Wenhui Rong, Xiaowei Zhang, Long Feng, Jiangyan Xu   +7 more
doaj   +1 more source

QTL analysis of leaf photosynthesis rate and related physiological traits in Brassica napus

Journal of Integrative Agriculture, 2015
Rapeseed (Brassica napus L.) oil is the crucial source of edible oil in China. In addition, it can become a major renewable and sustainable feedstock for biodiesel production in the future. It is known that photosynthesis products are the primary sources
Xing-ying YAN, Cun-min QU, Jia-na LI, Li CHEN, Lie-zhao LIU   +4 more
doaj   +1 more source

Genome-wide delineation of natural variation for pod shatter resistance in Brassica napus. [PDF]

PLoS ONE, 2014
Resistance to pod shattering (shatter resistance) is a target trait for global rapeseed (canola, Brassica napus L.), improvement programs to minimise grain loss in the mature standing crop, and during windrowing and mechanical harvest.
Harsh Raman, Rosy Raman, Andrzej Kilian, Frank Detering, Jason Carling, Neil Coombes, Simon Diffey, Gururaj Kadkol, David Edwards, Margaret McCully, Pradeep Ruperao, Isobel A P Parkin, Jacqueline Batley, David J Luckett, Neil Wratten   +14 more
doaj   +1 more source

The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton

Advanced Science, EarlyView.
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang, Jie Dai, Ting Zhao, Shengjun Zhao, Hongyu Wu, Jiaying Pan, Yupeng Hao, Ke Nie, Li Yu, Yumeng Zhu, Xiangyi Zhao, Kai Huang, Mengke Zhang, Yongyan Zhao, Yaping Jiang, Siyuan Wang, Yiling Pan, Yubing Chen, Yilai Lin, Wanghong Shi, Yayuan Deng, Jin Han, Jie Li, Xuan Long, Junbin Wang, Zhiyuan Zhang, Zegang Han, Zhanfeng Si, Lei Ju, Jun Li, Tianzhen Zhang, Ji Zhou, Xueying Guan   +32 more
wiley   +1 more source

Unifying genetic canalization, genetic constraint, and genotype-by-environment interaction: QTL by genomic background by environment interaction of flowering time in Boechera stricta. [PDF]

PLoS Genetics, 2014
Natural populations exhibit substantial variation in quantitative traits. A quantitative trait is typically defined by its mean and variance, and to date most genetic mapping studies focus on loci altering trait means but not (co)variances.
Cheng-Ruei Lee, Jill T Anderson, Thomas Mitchell-Olds   +2 more
doaj   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Fourteen Years of R/qtl: Just Barely Sustainable

Journal of Open Research Software, 2014
R/qtl is an R package for mapping quantitative trait loci (genetic loci that contribute to variation in quantitative traits) in experimental crosses. Its development began in 2000. There have been 38 software releases since 2001.
Karl W Broman
doaj   +1 more source