Results 71 to 80 of about 62,876 (219)

Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample [PDF]

, 2001
Miriam F. Moffatt, Carsten Schou, Jennifer A. Faux, Gonçalo R. Abecasis, Anthony James, Arthur W. Musk, William Cookson   +6 more
openalex   +1 more source

Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk

Advanced Science, EarlyView.
A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen, Benjamin Siciliano, Quan Wang, Chongchong Xu, Qiang Wei, Hai Yang, James S Sutcliffe, Yi Jiang, Ying Ji, Chunyu Liu, Feixiong Cheng, Edwin H Cook, Nancy J Cox, Xue Zhong, Zhexing Wen, Bingshan Li   +15 more
wiley   +1 more source

Automated quantitative trait locus analysis (AutoQTL). [PDF]

BioData Min, 2023
Freda PJ, Ghosh A, Zhang E, Luo T, Chitre AS, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, Lamparelli A, King CP, Palmer AA, Li R, Moore JH.   +19 more
europepmc   +1 more source

Hd1, a Major Photoperiod Sensitivity Quantitative Trait Locus in Rice, Is Closely Related to the Arabidopsis Flowering Time Gene CONSTANS

, 2000
Masahiro Yano, Yūichi Katayose, Motoyuki Ashikari, Utako Yamanouchi, Lisa Monna, Takuichi Fuse, Tomoya Baba, Kimiko Yamamoto, Yosuke Umehara, Yoshiaki Nagamura, Takuji Sasaki   +10 more
openalex   +2 more sources

Current Status of Quantitative Trait Locus Mapping in Livestock Species - Review - [PDF]

, 2001
Jong-Joo Kim, Young I. Park
openalex   +1 more source

Tumor‐Tissue Boundaries as Instructive Interfaces in Breast Cancer Cell Invasion

Advanced Science, EarlyView.
Tumor‐tissue boundaries reprogram metastatic breast cancer cells, enhancing invasiveness through an instructive, not permissive, mechanism. Using a 3D collagen I‐based tumor‐tissue interface model, single‐cell analysis, and simulations, this study shows that all cells can transmigrate without selective filtering, highlighting a targetable process in ...
Cornelia Clemens, Thomas Zerjatke, Andrine Frank, Hannah Trampert, Nataliia Kotsiuba, Ingmar Glauche, Tilo Pompe   +6 more
wiley   +1 more source

Consequences of Recombination Rate Variation on Quantitative Trait Locus Mapping Studies: Simulations Based on the Drosophila melanogaster Genome [PDF]

, 2001
Mohamed A. F. Noor, Aimee L. Cunningham, John C. Larkin   +2 more
openalex   +1 more source

A Coding SNP in GmPM30 Enhances Soybean Salinity Tolerance and Yield through the GmLEA1‐GmPM30‐GmLEC1 Module

Advanced Science, EarlyView.
A natural variation in soybean PM30, GmPM30‐HapT, confers greater salt tolerance than GmPM30‐HapC via stronger GmLEA1‐GmPM30‐GmLEC1 interactions. Pyramiding their elite haplotypes yields additive gains in salt tolerance and yield, establishing a novel workflow linking evolutionary genomics, molecular mechanisms, and breeding applications via the module
Shiyu Huang, Yuhan Xia, Jingting Yang, Yujun Si, Xue Chen, Hao Zhang, Tianshi Liu, Wenyu Zheng, Xin Chen, Zhongjuan Zhao, Xiaojian Zheng, Qing Lu, Shuo Li, Fengning Xiang   +13 more
wiley   +1 more source

Quantitative Trait Locus Analysis in Crosses Between Outbred Lines With Dominance and Inbreeding [PDF]

, 2001
Miguel Pérez‐Enciso, Rohan L. Fernando, Jean Pierre Bidanel, Pascale Le Roy   +3 more
openalex   +1 more source

Near‐Infrared‐Responsive Digital PCR‐Assisted Renal Cancer Exosomal miRNAs Insights and Regulation of Macrophage Polarization

Advanced Science, EarlyView.
A near‐infrared‐responsive digital Polymerase Chain Reaction technique with triple‐color coding profiles renal cancer exosomal microRNA biomarkers and their impact on macrophage polarization. Engineered miR‐34‐loaded exosomes via electroporation saturate molecular sponges, downregulating STAT3 in recipient macrophages to prolong M2 polarization. Stable
Lexiang Zhang, Rokshana Parvin, Siyue Lin, Peiyu Chen, Gangling Wang, Dingmeng Hu, Ke Lin, Yun Cheng, Fangfu Ye, Bing Han, Gen Yang, Dexuan Wang   +11 more
wiley   +1 more source