Results 71 to 80 of about 141,382 (327)

Quantitative Trait Locus Analysis of the Early Domestication of Sunflower [PDF]

Genetics, 2007
Abstract Genetic analyses of the domestication syndrome have revealed that domestication-related traits typically have a very similar genetic architecture across most crops, being conditioned by a small number of quantitative trait loci (QTL), each with a relatively large effect on the phenotype.
David M. Wills, John M. Burke
openaire   +3 more sources

The Role of Silicon Technology in Organ‐On‐Chip: Current Status and Future Perspective

Advanced Materials Technologies, EarlyView.
This review explores the potential of silicon micro‐nanofabrication technologies in advancing organ‐on‐chip systems. The integration of actuation and sensing modalities, highlight emerging technologies is discussed for combining silicon‐based and polymer‐based components, and emphasize the need for robust, high‐throughput, and customizable organ‐on ...
Frøydis Sved Skottvoll, Enrique Escobedo‐Cousin, Michal Marek Mielnik   +2 more
wiley   +1 more source

Fast empirical Bayesian LASSO for multiple quantitative trait locus mapping

BMC Bioinformatics, 2011
Background The Bayesian shrinkage technique has been applied to multiple quantitative trait loci (QTLs) mapping to estimate the genetic effects of QTLs on quantitative traits from a very large set of possible effects including the main and epistatic ...
Xu Shizhong, Huang Anhui, Cai Xiaodong
doaj   +1 more source

3D Printed Optics Achieves Broadband Structured Light

Advanced Optical Materials, EarlyView.
The arbitrary creation of structured light often requires complex design and fabrication steps and is largely limited to single wavelength. By leveraging off the toolkit for digital holograms, how complex amplitude modulation can be implemented as 3D printed optics in a manner that is broadband is shown, for the creation of multiwavelength forms ...
Leerin Perumal, Stefan Hengsbach, Moslem Mahdavifar, Jan Korvink, Andrew Forbes   +4 more
wiley   +1 more source

QTL analysis across multiple environments reveals promising chromosome regions associated with yield-related traits in maize under drought conditions

Crop Journal, 2021
Drought is one of the most critical abiotic stresses influencing maize yield. Improving maize cultivars with drought tolerance using marker-assisted selection requires a better understanding of its genetic basis.
Xinmin Hu, Guihua Wang, Xuemei Du, Hongwei Zhang, Zhenxiang Xu, Jie Wang, Guo Chen, Bo Wang, Xuhui Li, Xunji Chen, Junjie Fu, Jun Zheng, Jianhua Wang, Riliang Gu, Guoying Wang   +14 more
doaj  

The dissection of expression quantitative trait locus hotspots [PDF]

arXiv, 2015
Studies of the genetic loci that contribute to variation in gene expression frequently identify loci with broad effect on gene expression: expression quantitative trait locus (eQTL) hotspots. We describe a set of exploratory graphical methods as well as a formal likelihood-based test for assessing whether a given hotspot is due to one or multiple ...
arxiv  

Malignant Hepatoblast‐Like Cells Sustain Stemness via IGF2‐Dependent Cholesterol Accumulation in Hepatoblastoma

Advanced Science, EarlyView.
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding, Siwei Mao, Han Wu, Sijia Fang, Ni Zhen, Tianshu Chen, Jiabei Zhu, Xiaochen Tang, Xiaoyang Wang, Fenyong Sun, Guoqing Zhu, Qiuhui Pan, Ji Ma   +12 more
wiley   +1 more source

Novel Resampling Improves Statistical Power for Multiple-Trait QTL Mapping

G3: Genes, Genomes, Genetics, 2017
Multiple-trait analysis typically employs models that associate a quantitative trait locus (QTL) with all of the traits. As a result, statistical power for QTL detection may not be optimal if the QTL contributes to the phenotypic variation in only a ...
Riyan Cheng, R. W. Doerge, Justin Borevitz   +2 more
doaj   +1 more source

Map-based quantitative trait locus identification

Poultry Science, 1997
Poultry gene mappers chose microsatellites as the main source of genetic markers for poultry genome mapping, similar to the marker type used for other farm animals, laboratory animals, and humans. Optimal strategies for applying DNA markers in poultry populations are discussed, including the number of markers to be used, genome representation ...
openaire   +3 more sources

Model selection for quantitative trait locus analysis in polyploids [PDF]

Proceedings of the National Academy of Sciences, 2000
Over the years, substantial gains have been made in locating regions of agricultural genomes associated with characteristics, diseases, and agroeconomic traits. These gains have relied heavily on the ability to statistically estimate the association between DNA markers and regions of a genome (quantitative trait loci or QTL) related to a particular ...
Bruce A. Craig, Rebecca W. Doerge
openaire   +3 more sources