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Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits. [PDF]

open access: yesCell Genom
Chen CY   +14 more
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The Genetic Architecture of Quantitative Traits

Annual Review of Genetics, 2001
▪ Abstract  Phenotypic variation for quantitative traits results from the segregation of alleles at multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and external environments. Major challenges for biology in the post-genome era are to map the molecular polymorphisms responsible for variation in medically ...
Trudy Mackay
exaly   +3 more sources

Quantitative trait loci for behavioural traits in chickens

Livestock Production Science, 2005
Abstract The detection of quantitative trait loci (QTL) of behavioural traits has mainly been focussed on mouse and rat. With the rapid development of molecular genetics and the statistical tools, QTL mapping for behavioural traits in farm animals is developing.
Buitenhuis, A.J.   +9 more
openaire   +3 more sources

Quantitative trait loci for baseline erythroid traits

Mammalian Genome, 2006
A substantial genetic contribution underlies variation in baseline peripheral blood counts. We performed quantitative trait locus/loci (QTL) analyses to identify chromosome (Chr) regions harboring genes influencing the baseline erythroid parameters in F2 intercrosses between NZW/LacJ, SM/J, and C57BLKS/J inbred mice.
Peters, L L   +5 more
openaire   +2 more sources

Common disorders are quantitative traits

Nature Reviews Genetics, 2009
After drifting apart for 100 years, the two worlds of genetics - quantitative genetics and molecular genetics - are finally coming together in genome-wide association (GWA) research, which shows that the heritability of complex traits and common disorders is due to multiple genes of small effect size.
Plomin, Robert   +2 more
openaire   +3 more sources

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