Results 181 to 190 of about 837,128 (290)

Niche construction in quantitative traits: heritability and response to selection. [PDF]

Proc Biol Sci, 2022
Fogarty L, Wade MJ.
europepmc   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Improving genetic variant identification for quantitative traits using ensemble learning-based approaches. [PDF]

BMC Genomics
Sharma J, Jangale V, Shekhawat RS, Yadav P.   +3 more
europepmc   +1 more source

Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits. [PDF]

Bioinformatics, 2022
Zhou F, Butterworth AS, Asimit JL.
europepmc   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source

Phenotypic diversity of sorghum [Sorghum bicolor (L.) Moench] genotypes based on qualitative and quantitative traits. [PDF]

Heliyon
Gebre W, Mekbib F, Tirfessa A, Bekele A.
europepmc   +1 more source

Preference Matrix Guided Sparse Canonical Correlation Analysis for Genetic Study of Quantitative Traits in Alzheimer's Disease. [PDF]

Proceedings (IEEE Int Conf Bioinformatics Biomed), 2022
Sha J, Bao J, Liu K, Yang S, Wen Z, Cui Y, Wen J, Davatzikos C, Moore JH, Saykin AJ, Long Q, Shen L, ADNI.   +12 more
europepmc   +1 more source

Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants

Advanced Science, EarlyView.
The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley   +1 more source

Natural averaging may complement known biological constraints in sexual reproduction's advantages over asexual in conserving species quantitative traits. [PDF]

Sci Rep
Marron A, Szekely S, Cohen IR, Harel D.
europepmc   +1 more source

Inference about quantitative traits under selection: a Bayesian revisitation for the post-genomic era. [PDF]

Genet Sel Evol, 2022
Gianola D, Fernando RL, Schön CC.
europepmc   +1 more source