Results 121 to 130 of about 732 (170)

Cytotoxic quassinoids from Ailanthus altissima

Bioorganic & Medicinal Chemistry Letters, 2013
Two new quassinoids, altissinol A (1) and B (7), together with 12 known quassinoids, were isolated from the 95% ethanol extract of the barks of Ailanthus altissima. The structures of the new compounds (1 and 7) were determined on the basis of the spectroscopic methods including UV, IR, HR-ESI-MS, 1D and 2D NMR.
Yan, Wang, Wen-Jing, Wang, Chang, Su, Dong-Mei, Zhang, Li-Peng, Xu, Rong-Rong, He, Lei, Wang, Jian, Zhang, Xiao-Qi, Zhang, Wen-Cai, Ye   +9 more
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The Ever-Challenging Quassinoids

Synlett, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Quassinoids from Eurycoma longifolia

Journal of Natural Products, 2009
Ten new structurally diverse quassinoids (1-10) and 14 known compounds were isolated from the stems of Eurycoma longifolia. The new compounds were two eurycomanone-type C(20) quassinoids (1, 2), one klaineanone-type C(20) quassinoid (3), one C(19) quassinoid (4) with a 1,2-seco-1-nor-6(5-->10)-abeo-picrasan-2,5-olide skeleton, and six eurycomalactone ...
Katsunori, Miyake, Yasuhiro, Tezuka, Suresh, Awale, Feng, Li, Shigetoshi, Kadota   +4 more
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Antimalarial quassinoids: past, present and future

Expert Opinion on Drug Discovery, 2007
This review is a compilation of the investigations reported to date on the sources, isolation, chemistry and antimalarial activities of natural quassinoids and their synthetic and semisynthetic analogs. It also provides an analysis of the in vitro structure-activity relationship of quassinoids for further evaluation in animal models.
Ilias, Muhammad, Volodymyr, Samoylenko
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Quassinoid Bitter Principles

1973
The Simaroubaceae form a large botanical family of mostly pantropical distribution; only a few representatives (such as Ailanthus) extend into temperate regions. Many species of this family, for example Quassia amara L. (Surinam quassia) and Picraena excelsa Lindt. (=Picrasma excelsa Planch or Aeschrion excelsa Kuntze, Jamaica quassia, have been known,
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Cytotoxic Quassinoids from Cedronia granatensis

Journal of Natural Products, 1992
The NCI in vitro primary disease-oriented antitumor screen has been used to select and guide the fractionation of the organic and aqueous extracts of Cedronia granatensis. Two quassinoids, sergiolide [1] and isobrucein B [2], to which the screening panel cell lines exhibited up to a 1000-fold range of differential sensitivity, were isolated.
M, Tischler, J H, Cardellina, M R, Boyd, G M, Cragg   +3 more
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Activity of quassinoids as antifeedants against aphids

Journal of Chemical Ecology, 1989
A series of quassinoids was tested for antifeedant activity against the aphidMyzus persicae (Hemiptera, Aphididae). Isobrucein B, brucein B and C, glaucarubinone, and quassin decreased feeding at concentrations down to 0.05% and isobrucein A was effective at 0.01%.
J, Polonsky, S C, Bhatnagar, D C, Griffiths, J A, Pickett, C M, Woodcock   +4 more
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Quassinoids from Quassia indica

Phytochemistry, 1994
Abstract Four new quassinoids, indaquassins CF, were isolated from the bark of Quassia indica . Their structures were determined by spectroscopic and chemical evidence. In addition, known compounds, samaderines BE, dihydrosamaderine B, brucein D, soulameolide, cedronin and canthin-2,6-dione were also identified.
Kazuo Koike, Taichi Ohmoto
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Quassinoids from Picrasma javanica

Phytochemistry, 1990
Abstract Three new bitter principles, the des-4-methylated picrasane type quassinoids, javanicins H, I and J, were isolated from leaves of Picrasma javanica. The structures were determined by spectroscopic data and chemical evidence.
Kazuo Koike, Taichi Ohmoto
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Anti-HIV activity of quassinoids

Bioorganic & Medicinal Chemistry Letters, 1996
Abstract Eighteen quassinoid glycosides and nine known quassinoids were tested for inhibitory activity against HIV replication in H9 lymphocytic cells. Of the compounds tested, shinjulactone C ( 20 ) demonstrated the highest anti-HIV activity (EC 50 = 10.6 μM) in the absence of cytotoxicity with a therapeutic index of >25.
Masayoshi Okano, Narihiko Fukamiya, Kiyoshi Tagahara, Mark Cosentino, Thomas Tung-Ying Lee, Susan Morris-Natschke, Kuo-Hsiung Lee   +6 more
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