Results 11 to 20 of about 557 (166)

Integrated comparative metabolite profiling via NMR and GC–MS analyses for tongkat ali (Eurycoma longifolia) fingerprinting and quality control analysis [PDF]

Scientific Reports, 2023
Tongkat ali commonly known as Malaysian Ginseng (Eurycoma longifolia) is a herbal root worldwide available in nutraceuticals, either as a crude powder or capsules blended with other herbal products.
Ahmed Serag, Ahmed Zayed, Ahmed Mediani, Mohamed A. Farag   +3 more
doaj   +2 more sources

A Concise Enantioselective Approach to Quassinoids. [PDF]

J Am Chem Soc, 2022
A synthetic approach to quassinoids is described. The route to the tetracyclic core relies on an efficient and selective annulation between two unsaturated carbonyl components that is initiated by catalytic hydrogen atom transfer from an iron hydride to an alkene.
Thomas WP, Pronin SV.
europepmc   +5 more sources

Evaluating the Antiplasmodial Activity of <i>Picrasma javanica</i> Stem Bark Extract and Its Synergy With Artesunate in Rodent Malaria Models. [PDF]

Scientifica (Cairo)
Malaria remains a global health challenge, exacerbated by the emergence of drug‐resistant Plasmodium strains. This study evaluates the antimalarial activity of Picrasma javanica stem bark extract and its combination with artesunate (ART) in Plasmodium berghei–infected mice. The extraction yield using hexane at a 1:5 (w/v) ratio was 7.8% w/w.
Ounjaijean S, Somsak V.
europepmc   +2 more sources

Identification of Phytochemicals from the Water Extract of Eurycoma longifolia Roots using Solid-Liquid and Liquid-Liquid Extraction Based Fractionation Techniques

Acta Chimica Slovenica, 2021
Phytochemicals in the water extract of Eurycoma longofolia roots were identified using both solid-liquid and liquid-liquid extraction based fractionation techniques.
Lee Suan Chua, Abirame Segaran, Hoi Jin Wong   +2 more
doaj   +1 more source

Assessment of the Potential of the Invasive Arboreal Plant Ailanthus altissima (Simaroubaceae) as an Economically Prospective Source of Natural Pesticides

Diversity, 2022
The extensive use of pesticides may negatively affect human health. Additionally, it is one of the main reasons for the decline of pollinators and is thus a hazard for most crops and biodiversity as a whole.
Ekaterina Kozuharova, Ardalan Pasdaran, Abdel Rahman Al Tawaha, Teodora Todorova, Zheko Naychov, Iliana Ionkova   +5 more
doaj   +1 more source

Mechanisms Underlying the Therapeutic Effects of <i>Brucea javanica</i> in Cervical Cancer Treatment Based on Network Pharmacology and Molecular Docking. [PDF]

Int J Genomics
Aims: The aim of this study was to systematically analyze the role of Brucea javanica in the treatment of cervical cancer (CC) and its underlying mechanisms by means of network pharmacology and molecular docking. Background:Brucea javanica is a traditional Chinese herbal medicine used for the treatment of malaria and cancers, but its mechanism of ...
Jin W, Li B, Zhang L, Sun C, Liu Y.
europepmc   +2 more sources

Effect of protease inhibitors on the intraerythrocytic development of Babesia microti and Babesia duncani, the causative agents of human babesiosis. [PDF]

J Eukaryot Microbiol
Abstract Human babesiosis is a malaria‐like, tick‐borne infectious disease with a global distribution. Babesiosis is caused by intraerythrocytic, apicomplexan parasites of the genus Babesia. In the United States, human babesiosis is caused by Babesia microti and Babesia duncani.
Aderanti T, Marshall JM, Thekkiniath J.
europepmc   +2 more sources

Recent syntheses and biological profiling of quassinoids

Organic & Biomolecular Chemistry, 2022
Quassinoids exhibit diverse biological properties and pose synthetically challenging targets. Focusing on accomplishments over the past 15 years, we discuss strategies and tactics of total syntheses as well as SAR and biological functions.
Ethan J. Pazur, Peter Wipf
openaire   +3 more sources

Biological activity of neosergeolide and isobrucein B (and two semi-synthetic derivatives) isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae)

Memorias do Instituto Oswaldo Cruz, 2009
In the present study, in vitro techniques were used to investigate a range of biological activities of known natural quassinoids isobrucein B (1) and neosergeolide (2), known semi-synthetic derivative 1,12-diacetylisobrucein B (3), and a new semi ...
Ellen CC Silva, Bruno C Cavalcanti, Rodrigo CN Amorim, Jorcilene F Lucena, Dulcimar S Quadros, Wanderli P Tadei, Raquel C Montenegro, Letícia V Costa-Lotufo, Cláudia Pessoa, Manoel O Moraes, Rita CS Nunomura, Sergio M Nunomura, Marcia RS Melo, Valter F de Andrade-Neto, Luiz Francisco R Silva, Pedro Paulo R Vieira, Adrian M Pohlit   +16 more
doaj   +1 more source

Phytochemicals: Alternative for Infertility Treatment and Associated Conditions

Oxidative Medicine and Cellular Longevity, Volume 2023, Issue 1, 2023., 2023
Infertility and obstetric complications have become global health issues in the past few years. Infertility is defined as the inability of a couple to conceive even after twelve months or more of regular and unprotected intercourse. According to WHO data published in the year 2020, 186 million people have infertility globally.
Saziini H. Chorosho, Neha Malik, Gulsheen Panesar, Pratima Kumari, Sarita Jangra, Rupinder Kaur, Mariam S. Al-Ghamdi, Tasahil S. Albishi, Hitesh Chopra, Ravinder Singh, H. C. Ananda Murthy, Maria Silvana Alves   +11 more
wiley   +1 more source