Results 21 to 30 of about 22,884 (241)

Development of Fluorescent Aptasensors Based on G-Quadruplex Quenching Ability for Ochratoxin A and Potassium Ions Detection

Biosensors, 2022
G-quadruplexes have received significant attention in aptasensing due to their structural polymorphisms and unique binding properties. In this work, we exploited the fluorescence-quenching properties of G-quadruplex to develop a simple, fast, and ...
Cheng Yang, Xiaolin Chu, Li Zeng, Amina Rhouati, Fathimath Abbas, Shengnan Cui, Daiqin Lin   +6 more
doaj   +1 more source

Synthesis, Crystal Structure, Spectroscopic Characterization, DFT Calculations and Cytotoxicity Assays of a New Cu(II) Complex with an Acylhydrazone Ligand Derived from Thiophene

Inorganics, 2021
A new Cu(II) complex is synthetized by the reaction of copper nitrate and a N-acylhydrazone ligand obtained from the condensation of o-vanillin and 2-thiophecarbohydrazide (H2L). The solid-state structure of [Cu(HL)(H2O)](NO3)·H2O, or CuHL for simplicity,
María R. Rodríguez, Lucía M. Balsa, Oscar E. Piro, Gustavo A. Etcheverría, Javier García-Tojal, Reinaldo Pis-Diez, Ignacio E. León, Beatriz P. Parajón-Costa, Ana C. González-Baró   +8 more
doaj   +1 more source

Quencher‐Free, End‐Stacking Oligonucleotides for Probing Single‐Base Mismatches in DNA. [PDF]

ChemInform, 2006
[reaction: see text] Fluorescence can be quenched through PET from the fluorophore to neighboring C, T, and G bases, but not to the A moiety. The hairpin stem stability arising from pi-stacking and the PET between the pyrene-labeled 2'-deoxynucleotide units and their neighboring bases are the two main factors that affect the operation of these novel ...
Young Jun Seo, Jin Ho Ryu, Byeang Hyean Kim   +2 more
openaire   +1 more source

The study on the interaction of Epigallocatechin gallate with bovine serum Albumin

Proceedings of the Mongolian Academy of Sciences, 2020
In this study, we investigated the interaction of epigallocatechin gallate (EGCG) with bovine serum albumin (BSA) by fluorescence method and protein‐ligand docking. We separated EGCG from green tea using the chromatographic method and analyzed structural
Gombosuren Davaadulam, Maamuu Tamara, Nyamaa Gerelsuren   +2 more
doaj   +1 more source

A RuO2 Nanosheet as a Novel Quencher-free Platform for the Detection of Nucleic Acids in a Homogeneous Solution

Analytical Sciences, 2020
A fluorescent dye-labeled DNA probe was adsorbed and quenched on the monolayer of RuO2 nanosheets. Significant fluorescent recovery was observed upon the addition of complementary DNA due to desorption of the probe from the surface of the RuO2 nanosheet through duplex formation.
KITAMURA, Yusuke, TANIGUCHI, Takaaki, TSUTSUMI, Miwako, NURDIWIJAYANTO, Leanddas, MATSUO, Tomoya, KATSUDA, Yousuke, IHARA, Toshihiro   +6 more
openaire   +3 more sources

Recent Advances in the Preparation and Application of DNA-Encoded Metal Nanoclusters

Chemistry, 2023
DNA as an intriguing organic ligand has been widely employed for synthesizing metal nanoclusters and engineering their properties. This review aims to present recent progress on DNA-encoded metal (Ag, Cu, Au, Ag/Pt, Cu/Ag, etc.) nanoclusters (DNA-MNCs ...
Fang Yin, Jiangtao Ren, Erkang Wang
doaj   +1 more source

Quencher-free Linear Beacon Systems with Dual Fluorene-labeled Deoxyuridines

Bulletin of the Korean Chemical Society, 2011
The identification of natural genetic variation in human populations is arguably one of the most important spin-offs of the effort toward the completion of the Human Genome Project. Single nucleotide polymorphisms (SNPs) are the most abundant natural genetic variations in the human genome.
Yu-Jin Seo, Gil-Tae Hwang
openaire   +2 more sources

Photophysical study and in vitro approach against Leishmania panamensis of dicloro-5,10,15,20-tetrakis(4-bromophenyl)porphyrinato Sn(IV) [version 3; peer review: 2 approved]

F1000Research, 2021
Background: Photodynamic therapy activity against different biological systems has been reported for porphyrins. Porphyrin modifications through peripheral groups and/or by metal insertion inside the ring are main alternatives for the improvement of its ...
Fabián Espitia-Almeida, Carlos Diaz-Uribe, William Vallejo, Doris Gómez-Camargo, Arnold R. Romero Bohórquez, Cristian Linares-Flores   +5 more
doaj   +1 more source

Label-Free Homogeneous microRNA Detection in Cell Culture Medium Based on Graphene Oxide and Specific Fluorescence Quenching

Nanomaterials, 2021
Label-free homogeneous optical detection of low concentration of oligonucleotides using graphene oxide in complex solutions containing proteins remains difficult.
Florentin R. Nitu, Lorand Savu, Sorin Muraru, Ioan Stoian, Mariana Ionită   +4 more
doaj   +1 more source

Development and validation of a PCR-free nucleic acid testing method for RNA viruses based on linear molecular beacon probes

Journal of Nanobiotechnology, 2022
Background RNA viruses periodically trigger pandemics of severe human diseases, frequently causing enormous economic losses. Here, a nucleic acid extraction-free and amplification-free RNA virus testing probe was proposed for the sensitive and simple ...
Fuyu Du, Weijie Zhang, Huimin Yao, Yuqiong Xia, Xianghan Zhang, Peng Yang, Pengbo Ning   +6 more
doaj   +1 more source