Results 41 to 50 of about 281,649 (291)

Exciton-like luminescence of KCl matrix under thermoelastic, local and uniaxial deformation

Eurasian Journal of Physics and Functional Materials, 2022
The radiative relaxation of exciton-like formations in KCl-Na single crystal has been studied by exper-imental methods of luminescent spectroscopy. The amplifying effect of the radiation intensity with a maximum at 2.8 eV up to 500 times as compared to ...
K. Shunkeyev, A. Tilep, A. Lushchik, Sh. Sagimbayeva   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Effect of Necking Behavior and of Gap Size on the Cooling Rate in Hot Stamping [PDF]

Materials Research, 2016
In this study, a tailored die quenching experimental method using low closing pressures and an aluminum flat die was developed in order to evaluate the effects of the gap size on the cooling rate in the hot stamping process of a 22MnB5 steel grade ...
André Olah Neto, Guilherme Ourique Verran, Gabriel Carvalho Pissolatto, Rodinei Rocha Dutra   +3 more
doaj   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Quenching and blowup problems for reaction diffusion equations [PDF]

, 2004
In this thesis we study quenching and blowup problems for reaction diffusion equations with Cauchy-Dirichlet data. We give sufficient conditions for certain reaction terms under which quenching or blowup can occur.
Salin, Timo
core   +1 more source

New Model for Estimating the Volume of Martensite Transformed Using Acoustic Emission Measurements During an Induction Hardening Process

Metals
The accurate detection and quantification of martensitic transformation in steel during quenching are essential for controlling the resulting material properties. Numerous studies have investigated this phenomenon using Acoustic Emission (AE) techniques,
Erlantz Sola Llanos, Rafael Rodríguez, Marcos Aguirre, Carmelo Javier Luis-Pérez, Mario Javier Cabello   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

From 2,3-Diazabicyclo[2.2.2]oct-2-ene to Fluorazophore-L, a membrane-bound fluorescent probe for antioxidants [PDF]

, 2004
The aim of this work was to synthesize and to establish a new fluorescent membrane probe for antioxidants by exploiting the exceptional properties of the long-lived fluorophore 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) alias Fluorazophore-P.
Gramlich, Gabriela
core   +1 more source

The influence of coolant velocity on the local heat transfer coefficient during steel quenching [PDF]

Computer Methods in Materials Science, 2020
The results of the calculations of the local heat transfer coefficient HTC and a heat flux HF on the face of a cylindrical sample made of 1.0503 steel are presented. The sample was cooled from a temperature of approx.
Artur Szajding, Andrzej Gołdasz, Tadeusz Telejko   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source