Results 61 to 70 of about 478,349 (287)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Determination of Trace 55Fe and 63Ni in Steel Samples via Liquid Scintillation Counting

open access: yesApplied Sciences
In the decommissioning of nuclear facilities, activated steel often contains radionuclides such as 55Fe and 63Ni, which are categorized as hard-to-measure due to their emission of only low-energy beta particles or X-rays.
Giada Gandolfo   +3 more
doaj   +1 more source

Luminescent Oxygen Gas Sensors Based on Nanometer-Thick Hybrid Films of Iridium Complexes and Clay Minerals

open access: yesChemosensors, 2014
The use of Ir(III) complexes in photo-responsive molecular devices for oxygen gas sensing is reviewed. Attention is focused on the immobilization of Ir(III) complexes in organic or inorganic host materials such as polymers, silica and clays in order to ...
Hisako Sato   +2 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Jet Quenching Parameter with Hyperscaling Violation [PDF]

open access: yes, 2013
In this paper we study the behavior of jet quenching parameter in the background metric with hyperscaling violation at finite temperature.The background metric is covariant under a generalized Lifshitz scaling symmetry with the dynamical exponent z and ...
Heshmatian, S., Sadeghi, J.
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Effect of Graphite and Activated Carbon as Dispersed Particle in Base Fluid as Quench Medium on the Hardness of S45C Carbon Steel

open access: yesJournal of Materials Exploration and Findings, 2023
Adding a solid particle dispersion into a base fluid could increase its thermal conductivity, hence increasing the heat transfer characteristics. One example of this thermally enhanced fluid is in heat treatment industry as quench medium.
Wahyuaji Narottama Putra   +2 more
doaj   +1 more source

Calculating quenching weights [PDF]

open access: yesPhysical Review D, 2003
We calculate the probability (``quenching weight'') that a hard parton radiates an additional energy fraction due to scattering in spatially extended QCD matter. This study is based on an exact treatment of finite in-medium path length, it includes the case of a dynamically expanding medium, and it extends to the angular dependence of the medium ...
Salgado, Carlos A., Wiedemann, Urs Achim
openaire   +2 more sources

Catching galaxies in the act of quenching star formation [PDF]

open access: yes, 2018
Detecting galaxies when their star-formation is being quenched is crucial to understand the mechanisms driving their evolution. We identify for the first time a sample of quenching galaxies selected just after the interruption of their star formation by ...
Cimatti, Andrea   +4 more
core   +3 more sources

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