Results 71 to 80 of about 478,349 (287)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

quenching

, 2014
Citation: 'quenching' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.Q05007 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
  +4 more sources

Quenching of Star Formation [PDF]

, 2008
In the last decade we have seen an enormous increase in the size and quality of spectroscopic galaxy surveys, both at low and high redshift. New statistical techniques to analyse large portions of galaxy spectra are now finding favour over traditional ...
C. Jakob Walcher, Coryn A.L. Bailer-Jones, Gabriella de Lucia, Gerard Lemson, Jérémy Blaizot, Peter H. Johansson, Stéphane Charlot, Tamas Budavári, Vivienne Wild   +8 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Interrupted quenching in high carbon steels for forgings

Metalurgija, 2017
The present study is focused on analyzing the effect of the interrupted quenching followed by a partitioning process in a high carbon steel 0,50 % C, 1,50 % Mn, 0,40 % Si, 2,00 % Cr without significant contribution of Al.
G. Napoli, S. Mengaroni, M. Rallini, L. Torre, A. Di Schino   +4 more
doaj  

Quenched random graphs [PDF]

Journal of Physics A: Mathematical and General, 1994
9 pages, report CPTH-A264 ...
Bachas, C., de Calan, C., Petropoulos, P. M. S.   +2 more
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Error Propagation Analysis for Quantitative Intracellular Metabolomics

Metabolites, 2012
Model-based analyses have become an integral part of modern metabolic engineering and systems biology in order to gain knowledge about complex and not directly observable cellular processes. For quantitative analyses, not only experimental data, but also
Jana Tillack, Nicole Paczia, Katharina Nöh, Wolfgang Wiechert, Stephan Noack   +4 more
doaj   +1 more source

Quenching across quantum critical points: role of topological patterns

, 2010
We introduce a one-dimensional version of the Kitaev model consisting of spins on a two-legged ladder and characterized by Z_2 invariants on the plaquettes of the ladder.
Chen H.-D., Deng S., Diptiman Sen, Divakaran U., Dziarmaga J., Kibble T. W. B., Landau L., Smitha Vishveshwara   +7 more
core   +1 more source