Results 81 to 90 of about 478,349 (287)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Inhomogeneous thermal quenches [PDF]

Physical Review D, 2017
We describe holographic thermal quenches that are inhomogeneous in space. The main characteristic of the quench is to take the system far from its equilibrium configuration. Except special extreme cases, the problem has no analytic solution. Using the numerical holography methods, we study different observables that measure thermalization such as the ...
openaire   +2 more sources

Taking Care of Business in a Flash: Constraining the Timescale for Low-Mass Satellite Quenching with ELVIS

, 2015
The vast majority of dwarf satellites orbiting the Milky Way and M31 are quenched, while comparable galaxies in the field are gas-rich and star-forming.
Boylan-Kolchin, Michael, Bullock, James S., Cooper, Michael C., Fillingham, Sean P., Garrison-Kimmel, Shea, Wheeler, Coral   +5 more
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Quenching and Partitioning of Multiphase Aluminum-Added Steels

Metals, 2019
The quenching and partitioning response following intercritical annealing was investigated for three lean TRIP-type high-Al steel compositions. Depending on the intercritical austenite fraction following annealing, the steels assumed either a ferrite ...
Tuomo Nyyssönen, Olli Oja, Petri Jussila, Ari Saastamoinen, Mahesh Somani, Pasi Peura   +5 more
doaj   +1 more source

Quenching 2D Quantum Gravity

, 1994
We simulate the Ising model on a set of fixed random $\phi^3$ graphs, which corresponds to a {\it quenched} coupling to 2D gravity rather than the annealed coupling that is usually considered.
Agishtein, Agishtein, Ambjørn, Baillie, Baillie, Ben-Av, Bhatt, Binder, Boulatov, Brezin, Brezin, Burda, C.F. Baillie, Catterall, Catterall, D.A. Johnston, David, Distler, Dotsenko, Dotsenko, Dotsenko, Douglas, Edwards, Espriu, Gross, Itzykson, Janke, Johnston, Jurkiewicz, K.A. Hawick, Kawai, Kawai, Kazakov, Knizhnik, McCarthy, Mehta, Mezard, Wheater, Zhang   +38 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Thermo-Microstructural Numerical Simulation of Quenching Process of Steels

Journal of Advanced Materials in Engineering, 2011
In this work, a 3D thermo-microstructural model was developed to simulate the continuous cooling of steel. The model was employed for simulation of cooling process of the gears made from a plain carbon steel (AISI 1045) and a low alloy steel (AISI 4140).
M. Eshraghi Kakhki, A. Kermanpur, M. A. Golozar   +2 more
doaj  

Jet quenching

, 2004
Jet quenching studies play a prominent role in our current understanding of ultra-relativistic heavy ion collisions. In this review I first present the available formalism to compute medium-induced gluon radiation.
Armesto, N.
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source