Grape Seed Proanthocyanidins Modulate the Hepatic Molecular Clock via MicroRNAs
Molecular Nutrition &Food Research, Volume 66, Issue 23, December 2022., 2022 Jet‐lagged rats and HepG2 cells were used to evaluate if the activity of grape seed proanthocyanidins extract (GSPE) as modulator of hepatic clock genes is mediated by miRNAs. GSPE modulates expression of hepatic Bmal1 and miR‐27b‐3p. Moreover, cosinor‐based analysis reveals that both Bmal1 and miR‐27b‐3p expression follow a circadian rhythm and that ...
Francesca Manocchio +6 more
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Chlorogenic Acid: An In‐Depth Review of Its Effectiveness in Cancer Treatment
Cancer Nexus, EarlyView.ABSTRACT Cancer remains a formidable global health challenge. Owing to the unsatisfactory curative effects and severe side effects, it is urgent to explore safer and more effective therapeutic alternatives and drugs. Chlorogenic acid (CGA), a natural polyphenol, has emerged as a promising candidate for cancer therapy due to its multiple functions and ...
Bin Wang +9 more
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Animal BiotechnologyThe natural flavonoid quercetin, which exhibits a range of biological activities, has been implicated in liver disease resistance in recent research.
Ling Jiang, Rong Yi, Huan Chen, Shuwu Wu
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Rutin-induced beta-glucosidase activity in Streptococcus faecium VGH-1 and Streptococcus sp. strain FRP-17 isolated from human feces: formation of the mutagen, quercetin, from rutin [PDF]
, 1984 Ian Macdonald +3 more
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مجله دانشکده پزشکی اصفهان, 2013 Background: Quercetin is found in a wide range of food sources. Previous research has reported inconsistent findings about the effects of quercetin on inflammation and heart disease.
Maryam Zahedi +3 more
doaj
Design Principles Of Inorganic‐Protein Hybrid Materials for Biomedicine
Exploration, EarlyView.Inorganic protein hybrid materials (IPHMs) due to editable structure present unrivalled potential at the intersection of synthetic biology and materials science. The synthesis of IPHMs with a high degree of biosafety from bioactive units represents a shift in material design and synthesis.
Hao Liu +3 more
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FORMATION OF PROTOCATECHUIC ACID FROM QUERCETIN BY RAT KIDNEY IN VITRO
, 1958 Carl D. Douglass, Rose Hogan
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Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia
Exploration, EarlyView.We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
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Colouring Matters of the Corolla of Rhododendron obtusum f. hinode. I. The Isolation of Quercetin
, 1933 Kôzô Hayashi
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IκB Kinases α and β Show a Random Sequential Kinetic Mechanism and Are Inhibited by Staurosporine and Quercetin [PDF]
, 1999 Gregory W. Peet, Jun Li
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