Results 81 to 90 of about 452,508 (327)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

EquiX—A search and query language for XML [PDF]

Journal of the American Society for Information Science and Technology, 2002
AbstractEquiX is a search language for XML that combines the power of querying with the simplicity of searching. Requirements for such languages are discussed, and it is shown that EquiX meets the necessary criteria. Both a graph‐based abstract syntax and a formal concrete syntax are presented for EquiX queries.
Cohen, Sara, Kanza, Yaron, Kogan, Yakov, Nutt, Werner, Sagiv, Yehoshua, Serebrenik, Alexander   +5 more
openaire   +4 more sources

Object Query Computing Optimization in the Dynamic Information Model DIM

Моделирование и анализ информационных систем, 2011
The problem of algorithm for organization of the object queries execution [1] for a new object DBMS technology DIM [2] is considered such that the computational complexity of the queries execution is as little as possible.
V. S. Roublev
doaj  

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source

A query language for biological networks [PDF]

Bioinformatics, 2005
Abstract Motivation: Many areas of modern biology are concerned with the management, storage, visualization, comparison and analysis of networks, but no appropriate query language for such complex data structures yet exists. Results: We have designed and implemented the pathway query language (PQL) for querying large ...
openaire   +2 more sources

Conjunctive Query Answering for the Description Logic SHIQ

, 2011
Conjunctive queries play an important role as an expressive query language for Description Logics (DLs). Although modern DLs usually provide for transitive roles, conjunctive query answering over DL knowledge bases is only poorly understood if transitive
Glimm, Birte, Horrocks, Ian, Lutz, Carsten, Sattler, Ulrike   +3 more
core   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Integration of Relational and Graph Databases Functionally

Foundations of Computing and Decision Sciences, 2019
In today’s multi-model database world there is an effort to integrate databases expressed in different data models. The aim of the article is to show possibilities of integration of relational and graph databases with the help of a functional data model ...
Pokorný Jaroslav
doaj   +1 more source

Lost in translation? A multilingual Query Builder improves the quality of PubMed queries: a randomised controlled trial

BMC Medical Informatics and Decision Making, 2017
Background MEDLINE is the most widely used medical bibliographic database in the world. Most of its citations are in English and this can be an obstacle for some researchers to access the information the database contains. We created a multilingual query
Matthieu Schuers, Mher Joulakian, Gaetan Kerdelhué, Léa Segas, Julien Grosjean, Stéfan J. Darmoni, Nicolas Griffon   +6 more
doaj   +1 more source