Results 1 to 10 of about 387 (133)
International Journal of Electrochemical Science, 2013 The inhibiting effect of some quinazoline derivatives on the corrosion of carbon steel in 2 M HCl was studied by weight loss, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM) and energy ...
Hala M Hassan
exaly +3 more sources
Results in ChemistryThe rise of drug-resistant microbial pathogens necessitates the development of innovative antimicrobial agents. Quinazoline derivatives exhibit promising pharmacological effects and diverse chemical structures.
Vishwanath Halappanavar +3 more
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Molecules, 2014 A series of 2,4-disubstituted quinazoline derivatives were designed and synthesized. The biological results showed that most of quinazoline derivatives exhibited potent antiproliferative activities against a panel of three tumor cell lines and a good ...
Zeng Li, Li Zeng
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EXPLORING THE PROTEIN KINASE INHIBITORY ACTIVITY OF QUINAZOLINES AS ANTICANCER AGENTS: FDA-APPROVED DRUGS AND PROMISING REPORTED COMPOUNDS [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2023 Due to its powerful anticancer characteristics, the heterocyclic quinazoline has attracted a lot of interest in cancer research. Several cancer types, including lung, breast, colon, ovarian, and prostate cancers, have shown promise in response to ...
Abdelsalam Ouf +3 more
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A Review on the Synthesis and Chemical Transformation of Quinazoline 3-Oxides
Molecules, 2022 The synthesis of quinazoline 3-oxides and their derivatives has attracted considerable attention due to their reactivity as intermediates in the synthesis of quinazoline analogues and their ring-expanded derivatives.
Malose J. Mphahlele
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Quinazoline derivatives: synthesis and bioactivities [PDF]
Chemistry Central Journal, 2013 Owing to the significant biological activities, quinazoline derivatives have drawn more and more attention in the synthesis and bioactivities research. This review summarizes the recent advances in the synthesis and biological activities investigations of quinazoline derivatives. According to the main method the authors adopted in their research design,
Wang, Dan, Gao, Feng
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Computational investigation of quinazoline derivatives as Keap1 inhibitors for Alzheimer's disease
Informatics in Medicine Unlocked, 2023 The Keap1-Nrf2-ARE pathway is crucial in the antioxidant defense mechanism. The Keap1-Nrf2-ARE pathway has become an important target for the development of potent therapeutic agents for numerous diseases.
Sharmila Gote +4 more
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Antimicrobial and Cytotoxic Evaluation of New Quinazoline Derivatives [PDF]
Natural Product Communications, 2016 The synthesis of nine new quinazoline derivatives (2a-2i) and evaluation of their antimicrobial and cytotoxic activities were aims of the present work. For the synthesis of the compounds, 2-chloro-6,7-dimethoxyquinazolin-4-amine was used as the initial starting material.
Turan Zitouni, Gülhan +6 more
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COMPUTATION DESIGN OF QUINAZOLINE-4(3H)-ON DERIVATIVES AS CYCLOOXYGENASE-2 (COX-2) INHIBITOR
Jurnal Farmasi Sains dan Praktis, 2021 The 3-(benzylideneamino)-2-(2,4-dichlorophenyl)-quinazoline-4(3H)-ones (BDCQ) are compounds developed as anticancer drugs and quinazolines. The activity and bioavailability of BDCQ derivatives as anticancer compounds that inhibit COX-2 can be predicted ...
Anita Puspa Widiyana
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 The dual c-Met/vascular endothelial growth factor receptor 2 (VEGFR-2) TK inhibition is a good strategy to overcome therapeutic resistance to small molecules VEGFR-2 inhibitors.
Abdelfattah Hassan +6 more
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