Results 11 to 20 of about 623,955 (160)
Design and Molecular Docking Studies of Quinazoline Derivatives as Antiproliferation
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2018 Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell proliferation.
Anita Puspa Widiyana +4 more
doaj +2 more sources
The spectrogram data of quinazoline derivatives containing a dithioacetal moiety
Data in Brief, 2018 The nuclear magnetic resonance, and high-resolution mass spectrometry of quinazoline derivatives containing a dithioacetal moiety, which was hosted in the research article entitled “Syntheses, antiviral activities and induced resistance mechanisms of ...
Dandan Xie +9 more
doaj +2 more sources
Life, 2022 Quinazolines are a rich source of bioactive compounds. Previously, we showed NHE-1 inhibitory, anti-inflammatory, antiplatelet, intraocular pressure lowering, and antiglycating activity for a series of quinazoline-2,4(1H,3H)-diones and quinazoline-4(3H ...
Alexander Spasov +16 more
doaj +2 more sources
Bangladesh Journal of Pharmacology, 2015 The construction of dihydroisoindolo[2,1-a]quinazoline-5,11-dione derivatives (4a4m), by the condensation isatoic anhydride, appropriate amines and 2-formylbenzoic acid by using silica sulfuric acid as catalyst was reported.
Jun-Fei Zhang, Bo Liu, Cong-Xin Chen
doaj +2 more sources
Quinazoline pharmacophore in therapeutic medicine [PDF]
Bangladesh Journal of Pharmacology, 2016 This present study comprehensively expatiates the functionalized utilization of quinazoline scaffolds in drug development and furnishes latest updates in pharmacological appositeness of its derivatives in order to reveal novel pathways for therapeutic ...
Olayinka Oyewale Ajani +3 more
doaj +2 more sources
Reactions of organolithium reagents with quinazoline derivatives [PDF]
, 2012 This review deals with directed and regioselective lithiation of various quinazoline derivatives by the use of alkyllithiums in anhydrous THF at low temperature.
Hegazy, Amany S. +3 more
core +7 more sources
2-Azidobenzaldehyde-Enabled Construction of Quinazoline Derivatives: A Review. [PDF]
Int J Mol SciQuinazoline is a privileged heterocyclic scaffold commonly found in numerous pharmaceuticals and bioactive natural products, known for its diverse biological activities.
Qiu W, Zhan D, Ma X, Zhang X.
europepmc +2 more sources
New Tricyclic Aryl Quinazoline Derivatives by Suzuki-Miyaura Cross-Coupling. [PDF]
ChemistryOpenA number of new deoxyvasicinone (2,3‐dihydropyrrolo[2,1‐b]quinazolin‐9(1H)‐one) and mackinazolinone (6,7,8,9‐tetrahydro‐11H‐pyrido[2,1‐b]quinazolin‐11‐one) derivatives with aryl substituents at C7/C8 and at C5 are reported.
Elmuradov B +4 more
europepmc +3 more sources
COMPUTATION DESIGN OF QUINAZOLINE-4(3H)-ON DERIVATIVES AS CYCLOOXYGENASE-2 (COX-2) INHIBITOR
Jurnal Farmasi Sains dan Praktis, 2021 The 3-(benzylideneamino)-2-(2,4-dichlorophenyl)-quinazoline-4(3H)-ones (BDCQ) are compounds developed as anticancer drugs and quinazolines. The activity and bioavailability of BDCQ derivatives as anticancer compounds that inhibit COX-2 can be predicted ...
Anita Puspa Widiyana
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 The dual c-Met/vascular endothelial growth factor receptor 2 (VEGFR-2) TK inhibition is a good strategy to overcome therapeutic resistance to small molecules VEGFR-2 inhibitors.
Abdelfattah Hassan +6 more
doaj +1 more source