Results 21 to 30 of about 4,432 (113)

QUINIDINE IN FALCIPARUM MALARIA

The Lancet, 1981
Fourteen patients with falciparum malaria were successfully treated with oral quinidine. Twelve of these patients were followed for 35 days without recrudescence. In six patients the infection had already recrudesced after antimalarial treatment, which in two cases had included a full course of quinine.
Nicholas J. White, Nicholas J. White, Tan Chongsuphajaisiddhi, Tan Chongsuphajaisiddhi, David A. Warrell, David A. Warrell, Danai Bunnag, Danai Bunnag, Sornchai Looareesuwan, Sornchai Looareesuwan, Harinasuta T, Harinasuta T   +11 more
openaire   +3 more sources

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

The Journal of Clinical Pharmacology, Volume 65, Issue 8, Page 1026-1038, August 2025.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller, Lauren Lohmer, Felix Beck, Jeegar Patel, Jasminder Sahi   +4 more
wiley   +1 more source

Organocatalytic Enantioselective Synthesis of Oxindole‐4‐Aminopyrazolone Derivatives via Mannich Reaction of 3‐Substituted Oxindoles With Pyrazolinone Ketimines

Journal of Heterocyclic Chemistry, Volume 62, Issue 8, Page 496-504, August 2025.
Hydroquinine‐derived squaramide catalyzes the diastereo‐ and enantioselective Mannich reaction of pyrazolinone ketimines and 3‐aryl‐substituted oxindoles to access oxindole‐4‐aminopyrazolones with vicinal tetrasubstituted stereocenters. ABSTRACT The organocatalyzed Mannich reaction between pyrazolinone ketimines and 3‐aryl‐substituted oxindoles ...
María E. Molinero, Sandra Tejedor, Laura Martín, Alicia Maestro, José M. Andrés   +4 more
wiley   +1 more source

Quinidine syncope in children

Journal of the American College of Cardiology, 1987
Quinidine syncope and factors associated with it are well known among adult patients treated for cardiac arrhythmias. To define factors that may influence the occurrence of syncope in children taking quinidine, the clinical, anatomic, electrocardiographic, roentgenographic and pharmacologic data were compared in six patients with syncope (Group A) and ...
Macdonald Dick, Dennis C. Crowley, Catherine L. Webb, Amnon Rosenthal, Robert L. Spicer, Albert P. Rocchini, Robert H. Beekman, A. Rebecca Snider   +7 more
openaire   +3 more sources

Effects of Temperature, Na and K Concentration and Quinidine on Transmembrane Flux of K ⁴² and Incidence of Atrial Fibrillation [PDF]

, 1958
William C. Holland, Richard L. Klein
openalex   +1 more source

ARREST OF AURICULAR FIBRILLATION BY THE USE OF QUINIDINE. [PDF]

, 1921
Alan R. Ellis
openalex   +1 more source

THE INFLUENCE OF POTASSIUM CONCENTRATION ON THE ACTION OF QUINIDINE AND OF SOME ANTIMALARIAL SUBSTANCES ON CARDIAC MUSCLE [PDF]

, 1957
A. K. ARMITAGE
openalex   +1 more source

Thrombocytopenic Purpura Due to Quinidine [PDF]

, 1956
FREDERICK G. BOLTON
openalex   +1 more source

The Effect of Diphenylhydantoin Sodium (Dilantin), Procaine Hydrochloride, Procaine Amide Hydrochloride, and Quinidine Hydrochloride upon Ouabain-Induced Ventricular Tachycardia in Unanesthetized Dogs [PDF]

, 1954
Lois M. Mosey, Myra D. Tyler
openalex   +1 more source

Observations on the Thrombocytopenia Due to Hypersensitivity to Quinidine [PDF]

, 1954
Percy Barkham, Leandro M. Tocantins
openalex   +1 more source