Results 81 to 90 of about 31,612 (240)

Electrical Synapses Contribute to Sleep‐Dependent Declarative Memory Retention

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 2, January 2026.
Blocking electrical synapses (gap junctions) in healthy humans by mefloquine impaired the sleep‐dependent retention of verbal declarative memory and improved sensorimotor memory consolidation irrespective of sleep. Mefloquine also disrupted the coupling of sleep spindles to EEG slow oscillations in humans but did not affect hippocampal sharp‐wave ...
Gordon B. Feld   +9 more
wiley   +1 more source

In Silico Screening and Designing Synthesis of Cinchona Alkaloids Derivatives as Potential Anticancer [PDF]

open access: yes, 2017
P-glycoprotein (P-gp) resistance in cancer cells decreases intracellular accumulation of various anticancer drugs. This multidrug resistance (MDR) protein can be modulated by a number of non-cytotoxic drugs.
Hanafi, M. (Muhammad)   +4 more
core   +2 more sources

Myasthenia Gravis Outcomes After Use of Statins and Other Contraindicated Treatments: Results From the French National Insurance Database

open access: yesEuropean Journal of Neurology, Volume 33, Issue 1, January 2026.
In this real‐world study among 14,459 adults with MG, exposure to any contraindicated treatment was not significantly associated with risk of ICU admission for MG but was associated with significantly higher risk of death. In contrast, statins were associated with a greater risk of ICU admission but a lower risk of death.
Guilhem Solé   +7 more
wiley   +1 more source

In vitro evaluation of quinidine sensitivity in brazilian Plasmodium falciparum isolates: comparative analysis to quinine and chloroquine Avaliação da sensibilidade in vitro à quinidina em isolados brasileiros de Plasmodium falciparum: análise comparativa à quinina e à cloroquina

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2001
Falciparum malaria represents a serious and an increasing world public health problem due to the acquired parasite's resistance to the most available drugs.
Carla M. S. MENEZES   +4 more
doaj   +1 more source

Pharmacology of Antiarrhythmics: Quinidine, Beta-Blockers, Diphenylhydantoin, Bretylium [PDF]

open access: yes, 1973
The electrophysiologic effects of the antiarrhythmic drugs, presented elsewhere in this symposium, form only one of the bases for the selection of a therapeutic agent in any given clinical situation.
Proctor, Jack D., Wasserman, Albert J.
core   +1 more source

Reducing the oral quinine-quinidine-cinchonin (Quinimax) treatment of uncomplicated malaria to three days does not increase the recurrence of attacks among children living in a highly endemic area of Senegal [PDF]

open access: yes, 1996
A 3 d shortened course of the quinine-quinidine-cinchonin association Quinimax (trademark) was compared to the usual 7 d regimen for routinely treating 462 acute uncomplicated #Plasmodium falciparum$ malaria attacks in 72 children under the age of 10 ...
Brau, R.   +4 more
core   +1 more source

Catheter Ablation Is Associated With a Decrease in Major Adverse Cardiovascular Events and All‐Cause Mortality in Patients With Atrial Fibrillation and Obstructive Sleep Apnea

open access: yesJournal of Cardiovascular Electrophysiology, Volume 37, Issue 1, Page 36-45, January 2026.
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a common risk factor for the development and progression of atrial fibrillation (AF). Whether catheter ablation for AF management in patients with coexisting OSA yields survival benefit remains unclear.
Ghassan Bidaoui   +16 more
wiley   +1 more source

PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury [PDF]

open access: yes, 2016
BACKGROUND: Phase 3 trials supporting dextromethorphan/quinidine (DM/Q) use as a treatment for pseudobulbar affect (PBA) were conducted in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS).
Alexander, David N.   +12 more
core   +4 more sources

Exploring Isophorone‐Based Dienones: Comprehensive Insights Into Their Synthesis, Reactivity, and Diverse Applications

open access: yesJournal of Chemistry, Volume 2026, Issue 1, 2026.
Isophorone is an important motif in synthetic organic chemistry, as it is highly reactive and can get involved in a diverse array of functional group transformations to access various synthetic intermediates and molecular targets. In this context, an important group of compounds is the conjugated or nonconjugated isophorone‐cored dienones, which are ...
M. Saeed Abaee   +2 more
wiley   +1 more source

Installation of Trifluoromethylated Quaternary Carbon Stereocenters via Asymmetric Epoxidation of Tetrasubstituted Alkenes

open access: yesAdvanced Synthesis &Catalysis, Volume 367, Issue 23, December 11, 2025.
The catalytic enantioselective epoxidation of acyclic tetrasubstituted alkenes, bearing a trifluoromethyl group, is reported. In the presence of Takemoto's thiourea organocatalyst and tert‐butyl hydroperoxide, epoxides are obtained with excellent yield and good to high enantioselectivity.
Vincenzo Battaglia   +4 more
wiley   +1 more source

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