Results 101 to 110 of about 16,625 (226)

Quinidine for ventricular arrhythmias: a comprehensive review

International audienceQuinidine, the first antiarrhythmic drug, was widely used during the 20th century. Multiple studies have been conducted to provide insights into the pharmacokinetics and pleiotropic effects of Class Ia antiarrhythmic drugs. However,
Rakza, Redwane, Benali, Karim, Mabo, Philippe, Pavin, Dominique, Behar, Nathalie, J. Liang, Jackson, Leclercq, Christophe, Martins, Raphaël, P, Groussin, Pierre   +8 more
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Determination of quinidine, dihydroquinidine, (3S)-3-hydroxyquinidine and quinidine-N-oxide in plasma and urine by high-performance liquid chromatography

, 1994
A specific and sensitive method for the quantitation of quinidine, (3S)-3-hydroxyquinidine, quinidine N-oxide, and dihydroquinidine in plasma and urine has been developed. The method is based on a single-step, liquid—liquid extraction procedure, followed
Brøsen, Kim, Nielsen, Flemming, Nielsen, Karin Kramer   +2 more
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Effects of Quinine, Quinidine and Chloroquine on Human Muscle Nicotinic Acetylcholine Receptors

Frontiers in Pharmacology, 2018
The genus Cinchona is known for a range of alkaloids, such as quinine, quinidine, cinchonine, and cinchonidine. Cinchona bark has been used as an antimalarial agent for more than 400 years.
Günter Gisselmann, Desiree Alisch, Brigitte Welbers-Joop, Hanns Hatt   +3 more
doaj   +1 more source

Lack of response to quinidine in KCNT1-related neonatal epilepsy.

, 2018
OBJECTIVE: To evaluate the clinical efficacy and safety of quinidine in patients with KCNT1-related epilepsy of infancy with migrating focal seizures (EIMFS) in the infantile period and to compare with the effect of quinidine on mutant channels in vitro.
Li, Melody, Petrou, S, Sands, Tristan T, Li, M, Cilio, MR, Oldham, MS, Gazina, Elena, Patel, Akash, Datta, AN, Datta, Anita N, Petrou, Steven, Nair, U, Patel, A, Numis, AL, Numis, Adam L, Nair, Umesh, Gazina, E, Oldham, Michael S, Cilio, Maria-Roberta, Sands, TT   +19 more
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The effect of acute administration of quinidine, dextromethorphan and combination of dextromethorphan/quinidine on pentylenetetrazole-induced clonic and tonic seizure thresholds in mice

Fiyz̤, 2019
Background: Dextromethorphan (DM) as a non-opioid anti-cough has neuroprotective effects. Combination of DM with quinidine decreases rapid metabolism of DM to dextrorphan (DX). This study aimed to examine the effects of acute administration of quinidine,
Hassan Jamali , Azhdar Heydari
doaj  

Clinical features and basic mechanisms of quinidine-induced arrhythmias

, 1986
Quinidine therapy is one of the most common causes of the acquired long QT syndrome and the morphologically distinctive tachyarrhythmia torsade de pointes.
Roden, Dan M., Katherine A. Thompson, Brian F. Hoffman, Raymond L. Woosley, Woosley, Raymond L., Thompson, Katherine A., Hoffman, Brian F., Dan M. Roden   +7 more
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Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system

Malaria Journal, 2010
Background Concern over the potential cardiotoxicity of anti-malarial drugs inducing a prolonged electrocardiographic QT interval has resulted in the almost complete withdrawal from the market of one anti-malarial drug - halofantrine.
Kotaki Hajime, Yamada Harumi, Kinoshita Atsushi, Kimura Mikio   +3 more
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Disopyramide phosphate: is it just another quinidine

, 1978
We compared the effects of a therapeutic concentration of disopyramide with those of quinidine and lidocaine on the action potential characteristics and on the steady-state relationship between membrane potential and the maximum rate of rise of the ...
Teresa Kus, Betty I. Sasyniuk
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The clinical implication of changing unbound quinidine levels

, 1989
Pharmacodynamic and pharmacokinetic aspects pertinent to the potential clinical application of unbound quinidine levels were studied. Following heparin administration during electrophysiologic testing in 10 patients receiving quinidine, there were ...
Kessler, Kenneth M, Terracall, Elizabeth, Mahmood, Imrana, Kozlovskis, Patricia, Castellanos, Augustin, Wozniak, Paula M, Zaman, Liaqat, McAuliffe, Daneil, Trohman, Richard G, Myerburg, Robert J   +9 more
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The Synthesis of Quinidine Salicylate Ester Compound

, 2018
Quinidine a compound isolated from quinine plants, one of the species of quinine plants is (Chincona ledgereriana) From PT SIL Lembang. The purpose of this study was obtain quinidine salicylate ester through esterification reaction.
Ernawati, T. (Teni), Hanafi, M. (Muhammad), Lotulung, P. D. (Puspa), Nurjaya, I. (Intan), Mursiti, S. (Sri)   +4 more
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