Results 121 to 130 of about 16,625 (226)

Comparison of Assay Procedures Used to Measure Total and Unbound Concentrations of Quinidine

, 1989
Individualized quinidine dosing through the assessment of serum concentrations is warranted because of the wide variability observed in its pharmacokinetic behavior and its reported narrow therapeutic index.
Inger M. Darling, Ronald A. Wooding-Scott, Richard L. Slaughter   +2 more
core   +1 more source

Quinine impairs quinidine clearance in rat perfused liver

, 1993
We have examined the disposition of the cinchona alkaloids quinine and quinidine in the rat recirculating isolated perfused liver preparation. When administered as separate 1 mg doses, the hepatic clearances of quinine and quinidine were similar to the ...
George W Mihaly, Haydn Scott, Mark K Hyman, Richard A Smallwood, Denis J Morgan   +4 more
core   +1 more source

The diagnosis and management of atrial fibrillation in the horse

Veterinary Medicine: Research and Reports, 2015
M Kimberly J McGurrin Health Sciences Centre, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada Abstract: Atrial fibrillation is the most common performance-limiting arrhythmia in the horse.
McGurrin MKJ
doaj  

Sotalol versus quinidine for the maintenance of sinus rhythm after direct current conversion of atrial fibrillation.

, 1990
This open, parallel-group study compares quinidine and sotalol treatment for maintenance of sinus rhythm after direct current conversion of patients with chronic atrial fibrillation.
S Juul-Möller, N Rehnqvist-Ahlberg, N Edvardsson   +2 more
core   +1 more source

Quinidine pharmacodynamics in patients with arrhythmia: Effects of left ventricular function

, 1995
Objectives.This study was undertaken to determine whether quinidine pharmacodynamics are altered in the presence of left ventricular dysfunction.Background.Left ventricular function is an independent predictor of antiarrhythmic drug efficacy.
Henry J. Duff, D. George Wyse, Wyse, D. George, Gillis, Anne M., Margot McDonald, Mitchell, L. Brent, Duff, Henry J., McDonald, Margot, L. Brent Mitchell, Anne M. Gillis   +9 more
core   +1 more source

The effect of extract Kaempferia galanga rhizomes on the elimination kinetics of quinidine in rabbits

, 2005
The research was aimed to observe the effect of the juice of Kaempferia galanga rhizomes on quinidine elimination kinetics in rabbits. The study on interaction of extract Kaempferia galanga rhizomes to quinidine elimination kinetic was conductedly ...
Hakim, Lukman; Faculty of Pharmacy Universitas Gadjah Mada Yogyakarta, Hayati, Farida; Department of Pharmacy Faculty of Sciences and Mathematics Indonesia Islamic University Yogyakarta   +1 more
core   +1 more source

Mechanisms Underlying the Digoxin-Quinidine Interaction

, 1982
The clinically relevant interaction between quinidine and digoxin was investigated using unanesthetized and unrestrained guinea pigs for in vivo pharmacokinetic and tissue disposition as well as in vitro [’H]-digoxin binding studies using brain region ...
Geiger, Jonathan D.
core  

Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect

Neuropsychiatric Disease and Treatment, 2014
Kerri A Schoedel,1 Sarah A Morrow,2 Edward M Sellers3,4 1Altreos Research Partners, Inc., Toronto, 2Western University, London, 3DL Global Partners, Inc., Toronto, 4University of Toronto, Toronto, Ontario, Canada Abstract: Pseudobulbar affect (PBA) is ...
Schoedel KA, Morrow SA, Sellers EM
doaj  

Optical control of the cardiac rhythm with photoswitchable Na_V1.5 channel blockers. [PDF]

Nat Commun
Liu S, Guan W, Li Z, Wang W, Song H, Li J, Hou J, Wang H, Xiong J, Yang M, Yan N, Tian X, Li H, Huang Z.   +13 more
europepmc   +1 more source

From Diagnostic Mimicry to Diagnostic Clarity: Reframing Idiopathic Ventricular Fibrillation After Aborted Sudden Cardiac Death. [PDF]

JACC Case Rep
El-Battrawy I, Akin I, Khan M, van Heerebeek L, Hamdani N.   +4 more
europepmc   +1 more source