Results 81 to 90 of about 16,625 (226)
Quinidine-induced ventricular flutter and fibrillation without digitalis therapy
Three cases are described with documented ventricular flutter and fibrillation during quinidine medication without concomitant digitalis therapy. In all three patients the arrhythmia developed while they were receiving moderate doses of quinidine ...
Koster, R. W., Wellens, H. J.
core +1 more source
Falciparum malaria represents a serious and an increasing world public health problem due to the acquired parasite's resistance to the most available drugs.
Carla M. S. MENEZES +4 more
doaj +1 more source
Total Synthesis and Antimalarial Studies of Caelestines A–C
Total synthesis of caelestines A–C (alkaloids from the Australian ascidian, Aplidium caelestis) was accomplished, constituting the first synthesis of caelestines B and C. Caelestines A–C, with five other novel quinolones, were assessed against Plasmodium falciparum 3D7 and Dd2. Caelestine B was found to be a selective antimalarial alkaloid. Caelestines
Henry S. T. Smith +3 more
wiley +1 more source
Effect of Chiral Isomers Quinidine and Quinine Analogues on CYP2D6 Inhibition - A QSAR Investigation
Quinidine and quinine are the chiral isomers and CYP2D6 inhibitors. The stereochemistry difference results in the different inhibitory activity with quinidine being 2 orders of magnitude more potent than quinine.
艾纯芝, 杨凌, 邹汉法
core
Role of unstirred water layer in the exsorption of quinidine
Intestinal exsorption of salicylic acid, thiopentone, theophylline, and quinidine was measured during perfusion of the intestinal lumen with Tyrode solution. The effect of pectin or bovine serum albumin added to the perfusate on intestinal clearance (CL,)
Jin-Ding Huang
core +1 more source
Residue wise Root Mean Square Fluctuation (RMSF) of the C-alpha atoms of AKR1B1-Quinine, Quinidine; AKR1B10-Quinine, Quinidine complexes with time.
Syeda Abida Ejaz (4816971) +9 more
core +1 more source
Electrical Storms in Brugada Syndrome: Review of Pharmacologic and Ablative Therapeutic Options
Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in
Maury P, Hocini M, Haïssaguerre M
doaj
Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues
Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak +6 more
wiley +1 more source
A specific and sensitive assay for the separation and quantitation of quinidine, 3-hydroxyquinidine, quinidine-N-oxide, O-desmethylquinidine and dihydroquinidine is presented.
Nolan, P. E. +4 more
core +1 more source
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou +10 more
wiley +1 more source

