Results 91 to 100 of about 129,805 (284)

The disappearance of malaria from Denmark, 1862–1900

The Economic History Review, EarlyView.
Abstract The reason for malaria's disappearance from northwestern Europe in the early twentieth century has long been discussed but remains an unresolved conundrum. This is partially due to a previous focus on the early modern era, and partially because various theories have never been tested against each other.
Mathias Mølbak Ingholt, Maarten van Wijhe, Lone Simonsen, Daniel Weinberger   +3 more
wiley   +1 more source

Temperature changes in the course of treatment of severe malaria patients with artemether and quinine

Asian Journal of Medical Sciences, 2011
Objective: Severe malaria is a medical emergency with devastating multi-systemic effects, if not promptly treated with sensitive and safe drugs, death is imminent.
AA Osonuga
doaj   +1 more source

Cost of treating inpatient falciparum malaria on the Thai-Myanmar border. [PDF]

, 2014
BACKGROUND: Despite demonstrated benefits and World Health Organization (WHO) endorsement, parenteral artesunate is the recommended treatment for patients with severe Plasmodium falciparum malaria in only one fifth of endemic countries.
Chierakul, Wirongrong, Drake, Tom, Kyaw, Shwe Sin, Lubell, Yoel, Newton, Paul N, Ruangveerayuth, Ronatrai, White, Nicholas J   +6 more
core   +1 more source

Stereoselective Blockage of Quinidine and Quinine in the hERG Channel and the Effect of Their Rescue Potency on Drug-Induced hERG Trafficking Defect

International Journal of Molecular Sciences, 2016
Diastereoisomers of quinidine and quinine are used to treat arrhythmia and malaria, respectively. It has been reported that both drugs block the hERG (human ether-a-go-go-related gene) potassium channel which is essential for myocardium repolarization ...
Meng Yan, Pan Fan, Yanhui Shi, Lifang Feng, Junnan Wang, G. Zhan, Baoxin Li   +6 more
semanticscholar   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Preparation of N-doped carbon dots based on starch and their application in white LED [PDF]

, 2018
N-doped carbon dots (CDs) were synthesized simply and economically by a one-step hydrothermal method using starch as a carbon source and ethylenediamine (EDA) as a nitrogen dopant.
Chen, Yong, Liu, Xinghua, Liu, Xuguang, Yang, Yongzhen, Zheng, Jingxia   +4 more
core   +2 more sources

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

Alloxazine derivatives as multifunctional agents for photodynamic therapy, cancer cell imaging, and cell proliferation inhibition

Photochemistry and Photobiology, EarlyView.
Alloxazine photosensitizers, molecularly engineered through sugar conjugation and methoxy substitution to enhance solubility, photodynamic potency, and fluorescence, enable image‐guided photodynamic therapy while inhibiting cancer cell growth in the absence of photoactivation.
Rubej R. Khan, Sourav Kanti Seth, Reshma Mathew, Nitza V. Falcón‐Cruz, Chris Acquah, Steffen Jockusch, Liraz Levi, Carlos E. Crespo‐Hernández   +7 more
wiley   +1 more source

Comparison of artesunate and quinine in the treatment of severe Plasmodium falciparum malaria at Kassala hospital, Sudan

Journal of Infection in Developing Countries, 2014
Introduction: There is a need to investigate the treatment (artesunate and quinine) of severe malaria, as this will influence the outcome of morbidity and the mortality of the disease.
Tajeldin M Abdallah, Khalid A Elmardi, Asama H Elhassan, Mona B Omer, Mousab S Elhag, Mohamed A Desogi, Mohammed F Siddig, Ishag Adam   +7 more
doaj   +1 more source

Rocaglates as dual-targeting agents for experimental cerebral malaria [PDF]

, 2018
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity.
Ayi, Kodjo, Brown, Lauren E., Cencic, Regina, Crandall, Ian, Gros, Philippe, Kain, Kevin C., Kennedy, James M., Langlais, David, Moradin, Neda, Pelletier, Jerry, Porco, John A., Schmeing, Martin, Tarry, Michael J.   +12 more
core   +1 more source