Results 111 to 120 of about 104,109 (228)

Fluorescence Analysis of Quinine in Commercial Tonic Waters

open access: yesMethods and Protocols
Quinine is known for treating malaria, muscle cramps, and, more recently, has been used as an additive in tonic water due to its bitter taste. However, it was shown that excessive consumption of quinine can have severe side effects on health.
Artturi Harcher   +15 more
doaj   +1 more source

Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery

open access: yesSmall, Volume 22, Issue 26, 8 May 2026.
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk   +9 more
wiley   +1 more source

Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats. [PDF]

open access: yes, 2018
GPR139 is an orphan G protein-coupled receptor (GPCR) that is expressed mainly in the brain, with the highest expression in the medial habenula. The modulation of GPR139 receptor function has been hypothesized to be beneficial in the treatment of some ...
Conlisk, Dana   +5 more
core  

Light propagation and fluorescence quantum yields in liquid scintillators

open access: yes, 2015
For the simulation of the scintillation and Cherenkov light propagation in large liquid scintillator detectors a detailed knowledge about the absorption and emission spectra of the scintillator molecules is mandatory. Furthermore reemission probabilities
Buck, C., Gramlich, B., Wagner, S.
core   +1 more source

Growth Differentiation Factor‐15 Could Predict Decreased Hemoglobin in Tuberculosis Treated With Linezolid‐Containing Regimen

open access: yesThe Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
Baseline GDF‐15 predicts linezolid‐induced myelosuppression in rifampicin‐resistant tuberculosis. Patients with higher pretreatment GDF‐15 (> 950 pg/mL) were more likely to develop significant hemoglobin decline during therapy. Measuring GDF‐15 before treatment may help identify high‐risk patients and guide safer, personalized linezolid use.
Amaylia Oehadian   +10 more
wiley   +1 more source

Synthesis and pharmacological evaluation of fluoro/chloro-substituted acetyl and benzoyl esters of quinine as antimalarial agents

open access: yesResults in Chemistry
After establishment of the pharmacokinetic and toxicological profile of quinine derivatives using in silico approaches, this study reports the synthesis of new acetyl and benzoyl esters of quinine bearing one or more fluorine or chlorine atoms on the ...
Jean-Gonfi Mvondo Mbala   +15 more
doaj   +1 more source

Public health reforms and the mortality decline in nineteenth‐century Italy

open access: yesThe Economic History Review, Volume 79, Issue 2, Page 527-554, May 2026.
Abstract This study examines the impact of Italy's 1887–8 health reforms on mortality, contributing to the historical debate on the state's role in Europe's health transition. Leveraging event‐study‐style difference‐in‐differences approach, we assess the effectiveness of the Crispi–Pagliani reforms, which strengthened public health governance and ...
Francesco Maria Salvatore Fiore Melacrinis   +1 more
wiley   +1 more source

Nurses\u27 Alumnae Association Bulletin - Volume 5 Number 8 [PDF]

open access: yes, 1947
Calling All Nurses Financial Report Calendar of Events Lest You Forget! Attention Review of the Alumnae Association Meetings President\u27s Report Barton Memorial Division Oxygen Therapy Welcome, White Haven Alumnae Clinical Use of Penicillin in ...
Barth, Alice S   +12 more
core   +1 more source

The disappearance of malaria from Denmark, 1862–1900

open access: yesThe Economic History Review, Volume 79, Issue 2, Page 555-574, May 2026.
Abstract The reason for malaria's disappearance from northwestern Europe in the early twentieth century has long been discussed but remains an unresolved conundrum. This is partially due to a previous focus on the early modern era, and partially because various theories have never been tested against each other.
Mathias Mølbak Ingholt   +3 more
wiley   +1 more source

Nanoassemblies of an Artificial Ferric Enterobactin Analog for Biosensing Enterobacteriaceae

open access: yesChemElectroChem, Volume 13, Issue 8, 15 April 2026.
Nanoassemblies of an artificial trisamine‐based Ferric Enterobactin, analogs to natural enterobactin and ferric enterobactin, is reported as molecular recognition receptors for real‐time biosensing. The electrochemical sensors, made from the nanoassemblies of its iron(III)complex, exhibit rapid anodic peak current changes upon exposure to live cells of
Selina Laws   +4 more
wiley   +1 more source

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