Results 91 to 100 of about 50,177 (203)

Fluorescence Analysis of Quinine in Commercial Tonic Waters

open access: yesMethods and Protocols
Quinine is known for treating malaria, muscle cramps, and, more recently, has been used as an additive in tonic water due to its bitter taste. However, it was shown that excessive consumption of quinine can have severe side effects on health.
Artturi Harcher   +15 more
doaj   +1 more source

Postnatal developmental changes in the laryngeal chemosensory cell clusters of rats

open access: yesJournal of Anatomy, EarlyView.
Chemosensory cell clusters appeared in the rat larynx 2 days after birth and were already connected to afferent nerve fibers. Their number increased until 3 weeks of age, then stabilized while continuing to grow through the addition of new cells. Because their number reached a plateau around the time of weaning, their development may be linked to ...
Sayed Sharif Abdali   +5 more
wiley   +1 more source

Is Capsaicin Effective in Relieving the Symptoms of Burning Mouth Syndrome? A Systematic Review

open access: yesJournal of Oral Rehabilitation, EarlyView.
The capsaicin, administered topically or systemically, reduces pain symptoms in patients with Burning Mouth Syndrome (BMS). However, despite consistent clinical improvement, the current evidence is limited and of low certainty, highlighting the need for well‐designed studies to confirm its effectiveness. ABSTRACT Background Burning Mouth Syndrome (BMS)
Ana Paula de Andrade Silva   +7 more
wiley   +1 more source

A Case Report of Quinine-Induced Thrombotic Microangiopathy Successfully Treated With Eculizumab

open access: yesJournal of Investigative Medicine High Impact Case Reports
Drug-induced thrombotic microangiopathy (DITMA) is a life-threatening condition which may be immune or nonimmune mediated. Quinine is the most implicated drug in immune-mediated DITMA. However, the optimal treatment is unclear.
Jun Yen Ng BMedSci (Hons), MBBS, MClinTRes   +3 more
doaj   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor   +4 more
wiley   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia   +10 more
wiley   +1 more source

Barbituric Acids as Nucleophiles in Enantioselective Mannich Reactions: Organocatalytic Access to Quaternary Aminopyrazolone–Barbiturate Adducts

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
An enantioselective Mannich reaction using barbituric acids as nucleophiles provides access to chiral heterocycles bearing quaternary stereocenters. The transformation is catalyzed by a bifunctional thiourea with high selectivity. An immobilized catalyst enables recycling and application under continuous‐flow conditions, offering an efficient and ...
Rodrigo Sánchez‐Molpeceres   +4 more
wiley   +1 more source

Mechanochemistry as an Emerging Tool for Organofluorine Chemistry

open access: yesChemistry–Methods, Volume 6, Issue 8, August 2026.
Fluorinated scaffolds are central across many areas of chemistry, driving the demand for efficient and sustainable synthetic methods. Mechanochemistry has emerged as a powerful alternative to conventional approaches, offering reduced environmental impact, shorter reaction times, and unique reactivity and selectivity.
Marie Caldiero   +3 more
wiley   +1 more source

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong   +3 more
wiley   +1 more source

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