ELECTONIC STRUCTURE OF STRAINED HETEROCYCLIC SYSTEMS. QUINOLINE DERIVATIVES
Author Institution:Electronic structure calculations are reported for quinoline, 2,3-dimiethylquinoline, cyclobuta-B-quinoline, cyclopenta-B-quinoline and cyclobuta-G-quinoline, The fused rings perturb the calculated ionization potentials of the ...
Moomaw, William R. +2 more
core +1 more source
Waraporn Chan-on,1 Nguyen Thi Bich Huyen,2 Napat Songtawee,3 Wilasinee Suwanjang,1 Supaluk Prachayasittikul,3 Virapong Prachayasittikul2 1Center for Research and Innovation, 2Department of Clinical Microbiology and Applied Technology, 3Center of Data ...
Prachayasittikul V +5 more
core
Meniscus‐Guided Interfacial Ring‐by‐Ring Assembly for In Situ Fabrication of Tubular Hydrogels
A tubular hydrogel fabrication method leveraging the meniscus effect at the oil‐water interface is presented. UV irradiation across the concave surface of the photocurable hydrogel precursor induces the formation of ring‐like hydrogel structures. Sequential ring‐by‐ring assembly within microchannels enables the construction of arteriole‐scale hydrogel ...
Yuki Kamiya +2 more
wiley +1 more source
Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao +11 more
wiley +1 more source
Quinoline-Based Scaffolds in Anticancer Drug Discovery: Molecular Targets, Synthetic Strategies, and Biological Advances. [PDF]
Raza A, Wadhwa P, Sharma S.
europepmc +1 more source
Machine Learning for Synthetic Organic Chemistry: Methods, Applications, and Best Practices
Artificial intelligence (AI) and machine learning (ML) are increasingly reshaping experimental chemistry. This review maps the challenges of synthetic organic chemistry to modern digital tools that can help address them. While focusing on the practical application of ML tools in real‐world laboratory settings, we outline prerequisites, emerging ...
Niklas Hölter +3 more
wiley +1 more source
Bioinspired Quinoline-2 Derivatives Based on the Natural Alkaloid 2-Phenylquinoline from <i>Conchocarpus longifolius</i> (A.St.-Hil.) Kallunki & Pirani: Pharmacological Evaluation of Their Gastroprotective Potential. [PDF]
Fallone de Andrade S +8 more
europepmc +1 more source
ABSTRACT Endophytic fungi are recognized as prolific sources of structurally diverse secondary metabolites with significant pharmaceutical potential. In the present study, endophytic fungi were isolated from healthy tissues of Atalantia racemosa (Rutaceae), an ethnomedicinal plant traditionally used for respiratory disorders and blood purification.
Sushma M +3 more
wiley +1 more source
Synthesis, characterization, crystallography insights, and larvicidal activity of 4-substituted-8-(trifluoromethyl)quinoline derivatives against <i>Anopheles arabiensis</i>. [PDF]
Kotyan S +12 more
europepmc +1 more source
Heterocyclic‐Based Fungicides: Emerging Strategies for Viable Plant Disease Control
Heterocyclic compounds have attracted considerable attention because of their structural diversity, potent antifungal activity, and ability to interact with multiple fungal targets, offering broad‐spectrum protection against phytopathogens. Synthetic and semisynthetic/part‐natural scaffolds, particularly azole, quinoline, indole, cyclotryptamine, and ...
Sumit Tahlan +4 more
wiley +1 more source

