Results 121 to 130 of about 36,400 (237)

A Modular Synthesis of Isoindole/Indolizine Hybrids via the 1,3‐Dipolar Cycloaddition of Pyridine‐Based Mesoionics with Benzyne

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 26, 13 July 2026.
An approach to prepare pyrido[2,1‐a]isoindoles via the cycloaddition of pyridine‐based 1,3‐dipoles and benzyne is described, offering modular access to a range of substituted products by systematic tuning of the dipole. A modular strategy for the synthesis of fused indolizine/isoindole hybrids, pyrido[2,1‐α]isoindoles, via cycloaddition of pyridine ...
Samira Taghizadeh Nodehi   +2 more
wiley   +1 more source

Stafib‐2‐CR: an Improved Nanomolar and Selective Inhibitor of the Transcription Factor STAT5b Developed by Conformational Restriction of Stafib‐2

open access: yesChemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Conformational restriction strategies to increase the activity and selectivity of the STAT5b inhibitor Stafib‐2 are presented. The best conformationally restricted inhibitor Stafib‐2‐CR has threefold higher activity against STAT5b than Stafib‐2. A cell‐permeable prodrug of Stafib‐2‐CR inhibits phosphorylation of STAT5b in cultured human leukemia cells ...
Theresa Münzel   +5 more
wiley   +1 more source

Reprogramming RiPP scaffolds through skeletal editing unlocks chemical space. [PDF]

open access: yesChem Sci
Ogawa H   +8 more
europepmc   +1 more source

Quinoline Derivatives. (7)

open access: yesYAKUGAKU ZASSHI, 1962
Y, HAMADA, H, SUGIHARA
openaire   +3 more sources

Design, Synthesis, and Photophysical Studies of Functionalized Polyaromatic Isonitriles as Visible Light Photoredox Catalysts

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 25, 4 July 2026.
A new series of structurally rich polyaromatic isonitriles is presented as photoredox catalysts. Their photophysical properties are investigated by UV–Vis absorption and fluorescence measurements, combined with experimental and theoretical studies to evaluate both ground‐ and excited‐state redox properties.
Cristina Martini   +9 more
wiley   +1 more source

Bulky Monophosphine Ligand Synthesis by Nucleophilic Addition to Peri‐Functionalized Phosphine Isoindolium Salts

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 13, 2 July 2026.
In this article, we present a new modular approach for the synthesis of bulky monophosphine ligands by nucleophilic addition of Grignard reagents to peri‐phosphine isoindolium salts as stable building blocks. Outcompeting the established catalytic systems (PPh3)AuCl and (XPhos)AuCl, the phosphine gold complexes show high catalytic activity at low ...
Karl Georg Leistikow   +9 more
wiley   +1 more source

Structural Basis for Potent Inhibition of Human DHODH by Quinoline-4-carboxylic Acid Derivatives. [PDF]

open access: yesACS Omega
de Oliveira Viana J   +10 more
europepmc   +1 more source

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