Results 101 to 110 of about 38,082 (231)

Sulfur‐ and Selenium‐Decorated Coumarins: Synthetic Strategies Involving Cyclization and Late‐Stage Functionalization

The Chemical Record, EarlyView.
Two decades of synthetic strategies for sulfur‐, selenium‐decorated coumarins are critically surveyed through 44 literature reports, with particular emphasis on derivatives functionalized at the C‐3 and C‐4 positions. This review reports the direct construction of the coumarin framework through cyclization processes and late‐stage functionalization of ...
Bruna R. Schneider, Laura D. de Avila, Mauricio C. D. F. Xavier, Alex F. C. Flores, Liane K. Soares, Gabriel P. da Costa, Angelita M. Barcellos   +6 more
wiley   +1 more source

Metal‐Catalyzed Benzannulation: Recent Advances in Catalyst Design, Mechanistic Insights, and Aromatic Framework Construction

The Chemical Record, EarlyView.
This review offers a contemporary overview of metal‐catalyzed benzannulation (2018–present) encompassing transition, main‐group, post‐transition, and rare‐earth‐metal catalysts. It systematically highlights catalyst design, mechanistic insights, stereo‐ and regioselectivity, and synthetic applications toward aromatic and heteroaromatic scaffolds, while
Sana Jamshaid, Divya Shrestha, Raju S. Thombal, Jeung Gon Kim, Kim Seong Cheol, Yong Rok Lee   +5 more
wiley   +1 more source

Comparative Genome‐Wide Association Studies of Metabolites and Grain‐Related Traits in Common Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT The metabolome is highly diverse and the closest layer to phenotype; therefore, it is commonly regarded as a bridge between the genome and phenome in plants. Here, we performed large‐scale metabolome analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and 33 grain‐related traits in a diverse panel of natural accessions and
Guoguo Lv, Yanyan Liu, Bingyang Zhang, Ranran Shen, Maosong Yu, Yongyang Wu, Wanting Du, Xinru Yuan, Congwei Sun, Yan Yan, Wei Chen, Feng Chen   +11 more
wiley   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Thiolane Sulfoximines as Azide Surrogates for Quinolyl Nitrenes: Photochemical Access to Ortho‐Diaminoquinolines

Advanced Synthesis &Catalysis, Volume 368, Issue 21, 3 November 2026.
Thiolane sulfoximines provide practical and safer surrogates for hazardous azides in nitrene photochemistry, enabling direct access to 7,8‐diaminoquinolines and fused δ‐lactams. DFT calculations support the reaction mechanism and rationalize product selectivity.
Lorenzo Serusi, Timothé Maujean, Camille Van Wesemael, Romain Pertschi, Vicenç Branchadell, Mihaela Gulea   +5 more
wiley   +1 more source

Insights into Structure-Property Relationships in Quinoline-Based D-π-A Systems: A Synthetic and Computational Approach. [PDF]

Molecules
Rojas-Peña C, Espinosa-Saez R, Guzmán-Terán C, Jiménez CA, Ortega Villadiego A, Salazar JE, Orosco D, Rodríguez-Núñez YA, López JJ, Meléndez CM, Polo-Cuadrado E.   +10 more
europepmc   +1 more source

Quinoxaline–Triazole Hybrids: Exploring the Impact of Substituent Architecture on Cytotoxic Potency and Receptor Interaction

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
A series of title compounds was synthesized, with 6e and 6k exhibiting the lowest IC50 values against MCF‐7, HeLa, and HepG2 cancer cell lines. Molecular docking and dynamics revealed strong binding to the adenosine A1 receptor (ΔG = –9.02 and –9.24 kcal/mol).
Bangar Reddy Vancha, Mandapalli Sreeshitha, Shaik Farheen Banu, Kamala Prasad Vasikarla, Satyanarayana Swamy Vyshnava, Mukhriddin Makhkamov, Parthiban Marimuthu, Jamoliddin Razzokov, Aminul Islam, Peddiahgari Vasu Govardhana Reddy   +9 more
wiley   +1 more source

Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review). [PDF]

Mol Med Rep
Zeng Y, Yan Y, Wu S, Wu W, Chen K, Lai Y, Ye Q, Zhang N, Zhou Y.   +8 more
europepmc   +1 more source

Strain and Chirality: Catalytic Asymmetric Synthesis of Planar Chiral [2.2]Paracyclophanes

ChemistryEurope, Volume 4, Issue 11, November 2026.
Catalytic asymmetric synthesis is transforming access to planar‐chiral [2.2]paracyclophanes. This Review highlights recent advances in catalytic desymmetrization and asymmetric functionalization, emphasizing how catalyst design and PCP geometry govern reactivity and stereocontrol.
Daniel Alonso, Enrique Gómez‐Bengoa, Rosa López   +2 more
wiley   +1 more source

Salicylic Acid as a Food‐Derived Bioactive Constituent of Tiaoqi Daozhi Decoction: A Potential Functional Food Ingredient to Restoring Gut Barrier Function in Constipation‐Predominant IBS

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Tiaoqi Daozhi Decoction (TQDZD) is a classic formulation composed of eight medicine‐food homologous botanicals. UPLC‐MS/MS profiling identified 1962 non‐redundant compounds in its aqueous extract, predominantly phenolic acids and flavonoids, of which 107 metabolites were systemically bioavailable.
Min Duan, Lixia Huang, Yingyue Xu, Ya Huang, Xiaojun Yang   +4 more
wiley   +1 more source