Results 91 to 100 of about 56,164 (276)
Rapid and Efficient Microwave‐Assisted Friedländer Quinoline Synthesis
ChemistryOpen, 2020 A microwave‐based methodology facilitates reaction of 2‐aminophenylketones with cyclic ketones to form a quinoline scaffold. Syntheses of amido‐ and amino‐linked 17β‐hydroxysteroid dehydrogenase type 3 inhibitors with a benzophenone‐linked motif were ...
Dr. Helen V. Bailey +3 more
doaj +1 more source
Characterization of the Interaction of Known G‐quadruplex Ligands With a Minimal i‐Motif Structure
Chemistry – A European Journal, EarlyView.The destabilization of a minimal i‐Motif (iM) structure by TMPyP4 is driven by ligand recognition of one terminal iM structural domain. ABSTRACT Peculiar genomic regions are prone to evolve transiently from double‐helix DNA to noncanonical secondary structures in response to physiological stress.
Davide Auricchio +3 more
wiley +1 more source
KAT6A-inhibitor co-crystal structures: tackling a challenging crystallization target via two alternative approaches. [PDF]
Acta Crystallogr D Struct BiolWe report a novel cysteine‐to‐serine surface‐mutation approach to determine co‐crystal structures of KAT6A with small‐molecule inhibitors and compare it with the previously published MYSTcryst approach which uses mutated KAT8 as a surrogate for KAT6A.
Puetter V +8 more
europepmc +2 more sources
Chemistry – A European Journal, EarlyView.We report a cellular membrane‐targeted europium(III) probe, Eu.Chol, that enables selective, time‐resolved detection of peroxynitrite (ONOO−) at the cell membrane interface. Eu.Chol demonstrates efficient incorporation into liposomes and Jurkat cells, with minimal response to H2O2, establishing a modular platform for subcellular ONOO− sensing ...
Jamie Webb +6 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Five heteroleptic iridium(III) complexes bearing cyclometalated 2,4‐diphenylpyridinato ligands were synthesized and their electrochemiluminescence (ECL) investigated. Two different coreactants were evaluated: tri‐n‐propylamine and benzoyl peroxide under anodic and cathodic potentials, respectively.
Ovini Jayawardana +6 more
wiley +1 more source
A new synthesis of quinoline-5,8-quinone
, 1999 Sensitised photo-oxidations of 8-hydroxy quinoline (1) or 5-hydroxy quinoline (2) gives quinoline-5,8-quinone (3) in 64-70 ...
Amarasekara, Ananda S.
core +1 more source
ChemSusChem, Volume 18, Issue 6, March 15, 2025.The addition of Na2CO3 or K2CO3 to sewage sludge prior to combustion leads to the production of ashes containing phosphate in the form of buchwaldite‐like phases (Ca(Na/K)PO4). Compared to conventional sewage sludge mono‐ashes, such Na‐ or K‐ashes show greatly increased P‐solubilities and proved to be potent P‐fertiliser materials in greenhouse ...
Lorenz Bier‐Schorr +4 more
wiley +1 more source
The quinoline framework and related scaffolds in natural products with anti-Leishmania properties
Frontiers in ChemistryFor almost one hundred years, the quinoline heterocycle has been recognized as a privileged pharmacophore in anti-Leishmania agents. Early on, the action of compounds with this scaffold, found in some natural alkaloids, was tested against different ...
Gloria Yaluff +7 more
doaj +1 more source
Small organic molecules with electrochemically active functional groups can achieve high-density energy storage by the reversible Faraday reaction of multiple electrons.
Qiannan Sun (8140269) +6 more
core +1 more source
ChemSusChem, Volume 18, Issue 6, March 15, 2025.we have developed an electrochemical Ni−H catalyzed arylation coupling method of unactivated alkenes with aryl halides. The method displays broad functional group tolerance and proceeds under very mild conditions. Furthermore, aryl chlorides were also compatible substrates in this catalytic system. This conversion holds significant implications for the
Chao Xu, Ru‐Han A, Xiao‐Feng Wu
wiley +1 more source