Results 51 to 60 of about 103,486 (339)
A retrospective study of the efficacy and safety of levofloxacin in children with severe infection
Frontiers in PediatricsObjectivesLevofloxacin is widely used because of its broad-spectrum antimicrobial activity and convenient dosing schedule. However, the relevance of its use in children remains to be investigated.
Zhang Junqi +6 more
doaj +1 more source
Antibiotics, 2020 The introduction of antimicrobial residues in the food chain has a significant impact on human health. An innovative solution to avoid their presence in meat is the adaptation of current control methods for use with in vivo matrixes. Thus, the aim was to
María Jesús Serrano +11 more
doaj +1 more source
Sitafloxacin Expresses Potent Anti-Mycobacterium abscessus Activity
Frontiers in Microbiology, 2022 Therapeutic options for treating Mycobacterium abscessus infections are extremely limited; quinolones are important. The in vitro anti-M. abscessus activities of nine quinolones, emphasizing sitafloxacin, were investigated.
Siyuan He +12 more
doaj +1 more source
Reactive oxygen species play a dominant role in all pathways of rapid quinolone-mediated killing.
Journal of Antimicrobial Chemotherapy, 2019 BACKGROUND Quinolones have been thought to rapidly kill bacteria in two ways: (i) quinolone-topoisomerase-DNA lesions stimulate the accumulation of toxic reactive oxygen species (ROS); and (ii) the lesions directly cause lethal DNA breaks.
Yuzhi Hong +6 more
semanticscholar +1 more source
Crystal structure of ethyl 8-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C12H10ClNO3, the asymmetric unit comprises two independent molecules, and the dihedral angle between the least-square planes of the quinoline ring systems of these molecules is 73.30 (5)°.
Yoshinobu Ishikawa, Nanako Yoshida
doaj +1 more source
Mechanisms of quinolone resistance and implications for human and animal health [PDF]
Veterinarski Glasnik, 2010 Quinolone antibiotics have been widely used in human and veterinary medicine. This has caused the development of resistance and difficulties in the treatment of complicated bacterial infections in humans.
Velhner Maja +5 more
doaj +1 more source
Emerging Infectious Diseases, 2003 Ciprofloxacin resistance was analyzed in 354 Campylobacter jejuni isolates collected during two study periods (1995–1997 and 1998–2000) from travelers returning to Finland.
Antti Hakanen +4 more
doaj +1 more source
Review article: the global emergence of Helicobacter pylori antibiotic resistance. [PDF]
, 2016 BackgroundHelicobacter pylori is one of the most prevalent global pathogens and can lead to gastrointestinal disease including peptic ulcers, gastric marginal zone lymphoma and gastric carcinoma.AimTo review recent trends in H.
Aramin, H +6 more
core +1 more source
A Mild and Efficient Synthesis of 4-Quinolones and Quinolone Heterocycles [PDF]
The Journal of Organic Chemistry, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
D. L. Hughes +4 more
openaire +4 more sources
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao +6 more
wiley +1 more source