Results 101 to 110 of about 53,220 (228)

EVALUATION OF PLASMID-MEDIATED QUINOLONE RESISTANCE ASSOCIATED WITH THE QNR GENES IN CLINICAL ISOLATES OF SHIGELLA SPP. IN BAGHDAD

The Iraqi Journal of Medical Sciences, 2016
Background:Although quinolone resistance results mostly from chromosomal mutations in Enterobacteriaceae, it may also be mediated by plasmid-encoded qnr determinants. Shigella harboring the novel qnr plasmid-mediated mechanism of quinolone resistance has
Thanaa R. Abdulrahman, Qudus W. Jamal, Wurood A. Kadhim, Sabah A. Belal   +3 more
doaj   +4 more sources

Synthetic Ligands of Myeloid C‐Type Lectin Receptors

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley   +1 more source

[Mechanisms of bacterial resistance to quinolones].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2003
In order to produce their cytotoxic effect, quinolones must enter the cell through the bacterial membrane to reach their target, DNA-gyrase or topoisomerase IV, and induce cell death. The mechanisms of resistance to fluoroquinolones include: those mediated by gene mutations codifying for DNA gyrase and topoisomerase IV and leading to QRDR; those ...
Taléns Visconti, Raquel, Garrigues Pelufo, Teresa María, Cantón Lacasa, Emilia   +2 more
openaire   +2 more sources

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Mutations in quinolone resistance determining regions (QRDR) of representative quinolone resistant Shigella isolates.

Mutations in quinolone resistance determining regions (QRDR) of representative quinolone resistant Shigella isolates.
Gourab Halder (17996514), Debjani Ghosh (450836), Kei Kitahara (272466), Thandavarayan Ramamurthy (283406), Alok K. Deb (17996517), Masatomo Morita (3743848), Puja Bose (10975042), Goutam Chowdhury (591307), Shin-ichi Miyoshi (3743851), Shanta Dutta (185742), Asish Kumar Mukhopadhyay (8558736)   +10 more
core   +1 more source

Prevalence and characteristics of quinolone resistance in Escherichia coli in veal calves

, 2012
Quinolone resistance is studied and reported increasingly in isolates from humans, food-producing animals and companion animals. Resistance can be caused by chromosomal mutations in topoisomerase genes, plasmid-mediated resistance genes, and active ...
Dep Infectieziekten Immunologie, Advances in Veterinary Medicine, Veldman, K.T., Dik Mevius, Hordijk, J., Mevius, D.J., Joost Hordijk, van Essen-Zandbergen, A., Alieda van Essen-Zandbergen, Kees Veldman, Dierikx, C.M., Cindy Dierikx, I&I AVM, Mevius, D., Wagenaar, J.A., Veldman, K., Jaap A. Wagenaar   +16 more
core   +1 more source

How Host Phylogeny, Diet, and Habitat Affect Gut Microbial Diversity in Wild Snakes

Ecology and Evolution, Volume 16, Issue 7, July 2026.
Gut microbiota plays critical roles in host digestion, immune regulation, neurochemical signaling, and metabolic homeostasis. Based on wild snakes (73 individuals from 23 species) from China, we explored the composition, characteristics, and functions of gut microbes across different groups using fecal metagenomic samples; further we explored the ...
Jiaqi Zhang, Chunmei Fu, Songwen Tan, Bing Lyu, Guocheng Shu, Lei Shi, Yayong Wu, Peng Guo   +7 more
wiley   +1 more source

Consumption of antibiotics at St Luke’s Hospital : a critical factor behind the local prevalence of antimicrobial resistance? [PDF]

, 2006
The intensity of antibiotic use in hospital settings is recognised as possibly the most important factor for the selection of antimicrobial resistance. Hospitals are therefore being encouraged to undertake surveillance and benchmarking of antimicrobial ...
Borg, Michael Angelo, Zarb, Peter
core  

Trends in Enterobacteriaceae Resistance Patterns: A Nine‐Year Retrospective Study From North Lebanon

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Antimicrobial resistance (AMR) in Enterobacteriaceae poses a critical threat to global health, particularly in regions where antibiotic misuse and limited surveillance prevail. Intensive care units (ICUs) act as focal points for resistance emergence and dissemination. This study aimed to evaluate long‐term resistance trends
Mazen Zaylaa, Maya El Bitar, Ali Jaafar, Majd Hammoud, Hiba El Chakra, Abdul Rahman Maaliki, Farah El Dali, Dina Awad, Yasmine Hijazi, Omar El Gharbawy, Ricardo Sarraf, Ibtihal Kassam, Diala Wehbe   +12 more
wiley   +1 more source

Genetic bases of quinolone resistance

, 2010
Bakteriyel direnç, tür çeşitliliği ve biyolojik etkileşim dolayısıyla genetik değişimlerin kolayca oluşabildiği genetik reaktörlerde ortaya çıkar. Son yıllarda kinolon direnci ve kalıntıları, bu gruptaki antibiyotiklerin yaygın kullanımı nedeniyle yoğun ...

core