Results 111 to 120 of about 3,523,720 (291)

Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance

Molecules, 2020
Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times. They have enjoyed over 30 years of clinical usage and become essential tools in the armoury of clinical treatments. FQs target the bacterial enzymes DNA gyrase and
Natassja G. Bush, Isabel Diez-Santos, Lauren R. Abbott, Anthony Maxwell   +3 more
doaj   +1 more source

The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]

, 2003
Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E, Gillespie, SH, Gosling, RD, Kanduma, EG, Morris, RW, Nyindo, M, Sam, NE, Uiso, LO   +7 more
core   +1 more source

‘Knowledge, attitudes and practices’ survey of Austrian veterinarians' antibiotic use in clinical practice

Veterinary Record, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is a critical global health issue, with antimicrobial use (AMU) in veterinary medicine playing a relevant role in its emergence. This study aimed to evaluate the knowledge, attitudes and practices of Austrian veterinarians regarding AMU and AMR.
Clair L. Firth, Patricia Mayer, Annemarie Käsbohrer, Tanja Tripolt, Klemens Fuchs   +4 more
wiley   +1 more source

Occurrence of Extended-Spectrum Beta-Lactamase and Quinolone Resistance Genes among Escherichia coli and Klebsiella pneumoniae Isolated from Poultry, Domestic Pigs and Environ in Msimbazi River Basin in Tanzania

Journal of Applied Sciences and Environmental Management
We investigated the occurrence and distribution of genes encoding for extended-spectrum beta-lactamase (ESBL) production and quinolone resistance among multi-drug resistant (MDR) Escherichia coli and Klebsiella pneumoniae isolated from poultry, domestic
Z. I. Kimera, F. X. Mgaya, S. E. Mshana, E. D. Karimuribo, M. I. N. Matee   +4 more
doaj   +1 more source

Maintenance of Microbial Cooperation Mediated by Public Goods in Single- and Multiple-Trait Scenarios [PDF]

, 2017
Microbes often form densely populated communities, which favor competitive and cooperative interactions. Cooperation among bacteria often occurs through the production of metabolically costly molecules produced by certain individuals that become ...
Balbontín, Roberto, Dionisio, Francisco, Xavier, Karina Bivar, Özkaya, Özhan   +3 more
core   +1 more source

Exposure to Systemic Antimicrobials During Pregnancy and Risk of Miscarriage: A Population‐Based Registry Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill, Marleen M. H. J. van Gelder, Hilde M. Engjom, Hedvig M. E. Nordeng   +3 more
wiley   +1 more source

Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time‐to‐resolution

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth, Antonio Filipe Macedo, Sofia Somajo, Lukas Tannerfeldt, Baris Toprak, Neil Lagali   +5 more
wiley   +1 more source

Chlorpromazine inhibits the plasmid-mediated oqxAB multidrug efflux pump in Escherichia coli isolates of Egyptian patients with utis

BMC Microbiology
Over the past ten years, the prevalence of the OqxAB efflux pump, a plasmid-mediated quinolone resistance determinant, has increased among Escherichia coli (E. coli) isolates.
Kholoud Baraka, Rania Abozahra, Fatma Okda, Sarah M. Abdelhamid   +3 more
doaj   +1 more source

Changes in the Dispensing of Antibiotics to Australian Children Between 2013 and 2023: Are We Heading in the Right Direction?

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Antimicrobial resistance (AMR) poses a critical public health issue, exacerbated by the overuse and misuse of antibiotics. Children are particularly susceptible to bacterial infections and are frequently prescribed antibiotics. Objective This study examined trends in antibiotic dispensing to children aged under 13 years in Australia
Erin Kelty, Ella Tairy, Scott Sims, Carol Orr, Amy Page, David B. Preen, Frank M. Sanfilippo, Christopher Etherton‐Beer, Ebony Quintrell   +8 more
wiley   +1 more source

Characterization of quinolone resistance in Salmonella spp. isolates from food products and human samples in Brazil

Brazilian Journal of Microbiology, 2016
Non-typhoidal salmonellosis is an important zoonotic disease caused by Salmonella enterica. The aim of this study was to investigate the prevalence of plasmid-mediated quinolone resistance in Salmonella spp.
B. Pribul, M. L. Festivo, Miliane M. S. de Souza, Dália dos Prazeres Rodrigues   +3 more
semanticscholar   +1 more source