Results 91 to 100 of about 2,195,251 (142)

Comparative Genomic Analysis of Multidrug‐Resistant Escherichia coli Across Poultry–Human–Environmental Interfaces

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Whole‐genome sequencing analysis of Escherichia coli isolates from broiler, layer and sonali chickens in Bangladesh shown extensive antimicrobial resistance, diverse virulence factors, plasmid‐mediated resistance, and a highly open pangenome. Comparative genomic analyses demonstrated close genetic relationships with global strains, highlighting the One
Md. Rokibul Hasan Shanto, A. S. M. Ashab Uddin, Md. Shakil Mahmud Supto, Nabil Jahan Mahim, Md. Matiar Rahman Howlader, Syed Sayeem Uddin Ahmed, Md Bashir Uddin   +6 more
wiley   +1 more source

Mechanism of quinolone resistance in anaerobic bacteria [PDF]

, 2003
Several recently developed quinolones have excellent activity against a broad range of aerobic and anaerobic bacteria and are thus potential drugs for the treatment of serious anaerobic and mixed infections.
Oh, H, Edlund, C., Edlund, Charlotta,, Edlund, C, Oh, H.   +4 more
core   +1 more source

Genomic Detection of Multidrug‐Resistant H58 ST1 Salmonella Typhi in a South African Urban Waterway Reveals Epidemiological Links With Clinical Isolates

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Genomic analysis of four S. Typhi from a South African urban river uncovered two multidrug‐resistant H58 strains carrying qacEΔ1, revealing strong phylogenetic links to clinical isolates and underscoring urban rivers as potential transmission pathways. ABSTRACT Typhoid fever remains a major public health concern in South Africa.
Sanelisiwe Thinasonke Duze, Musa Marimani, Mrudula Patel   +2 more
wiley   +1 more source

Genetic bases of quinolone resistance

, 2010
Bakteriyel direnç, tür çeşitliliği ve biyolojik etkileşim dolayısıyla genetik değişimlerin kolayca oluşabildiği genetik reaktörlerde ortaya çıkar. Son yıllarda kinolon direnci ve kalıntıları, bu gruptaki antibiyotiklerin yaygın kullanımı nedeniyle yoğun ...

core  

Interrogating the Escherichia coli Epitranscriptome Via CRISPR Interference and Nanopore Native RNA Sequencing

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Epitranscriptomics is understudied in bacteria but has the ability to modulate antimicrobial resistance, virulence and pathogenicity. Pitt et al. implement two cutting‐edge techniques: CRISPR interference and Nanopore direct RNA sequencing along with functional assays to study RNA modifications in Escherichia coli.
Miranda E. Pitt, Jianshu Zhang, An N. T. Nguyen, Michael B. Hall, Leila Jebeli, Leo A. Featherstone, Garry S. A. Myers, Nichollas E. Scott, Lachlan J. M. Coin   +8 more
wiley   +1 more source

The Prevalence of Plasmid-mediated Quinolone Resistance Genes in Escherichia coli Isolated from Hospital Wastewater Sources in Tehran, Iran

Iranian Journal of Public Health, 2017
Background: Considering the importance of hospital wastewaters as potential reservoirs for the dissemination of bacterial pathogens such as Escherichia coli and antibiotic resistance genes in the environment, the need for such information becomes ...
Reza RANJBAR, Omid FARAHANI
doaj  

Proteomic Analysis of Three Independent Series of Sequential Cystic Fibrosis Strains in an International Pseudomonas aeruginosa Reference Panel Indicates Positive Selection in Late Infection Strains

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Comparison of proteomes from three series of sequential Pseudomonas aeruginosa isolates from people with cystic fibrosis identified eleven proteins with increased abundance in at least one late isolate per patient. Three proteins were increased in all five late isolates, and the probability of this occurring by chance is 5.06 × 10−53, indicating strong
Joanna Drabinska, Lucia O'Connor, Caoilin McClean, Siobhán McClean   +3 more
wiley   +1 more source

Iran's Escherichia coli AMR Landscape (2010–2025): A One Health Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This One Health systematic review and meta‐analysis of 368 studies (2010–2025) reveals that 47.2% of E. coli isolates in Iran are ESBL‐producers, with alarming resistance to penicillins, cephalosporins, and fluoroquinolones. Critically, resistance to last‐resort antibiotics—colistin and ertapenem—is significantly increasing over time.
Arezoo Dehghan, Mina Arabian, Zahra Tahmasebi, Aliasghar Fakhri‐Demeshghieh, Neda Baseri, Ehsan Mostafavi, Farzad Badmasti, Faranak Abnaroodhelleh, Arash Seifi, Fahimeh Bagheri Amiri   +9 more
wiley   +1 more source

Quinolone Analogue Inhibits Tubulin Polymerization and Induces Apoptosis Via Cdk1-Involved Signaling Pathways

, 2008
Cancer chemotherapeutic agents that interfere with tubulin/ microtubule function are in extensive use. Quinolone is a common structure in alkaloids and its related components exhibit several pharmacological activities.
陳依呈;潘秀玲;鄧哲明;郭盛助;林宗平;何藴芳;黃煜珺;顧記華, CHEN, YING-CHENG;PAN, SHIOW-LIN;TENG, CHE-MING;KUO, SHENG-CHU;LIN, TSUNG-PING;HO, YUNN-FANG;HUANG, YU-CHUN;GUH, JIH-HWA   +1 more
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First Report of blaCTX‐M‐15 in a Marine Thermotolerant Enterobacter Isolate From Bangladesh: Genomic Insights Into Halotolerance and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Marine‐derived Enterobacter kobei, exhibiting thermotolerance and salt tolerance, is ESBL‐producing and harbors AMR genes (blaCTX‐M‐15, qnrS1) and mobile genetic elements, indicating environmental spread of antimicrobial resistance. ABSTRACT Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on
Md. Arifur Rahman, Rafid Muntasir Ul Azam, Md. Sazib Hossain, Samina Momtaz, Anowara Begum, Munawar Sultana   +5 more
wiley   +1 more source