Results 91 to 100 of about 3,523,720 (291)

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]

, 2011
BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Fang, K., Zhao, H., Changyue Sun, Lam, M.C., Chang, S., Zhang, K., Panda, G., Godinho, M., Martins Dos Santos, V.A.P., Wang, J.   +9 more
core   +2 more sources

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

Journal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou, Xiucai Zhang, Zhenjie Chen, Chao Fang, Shixing Liu, Jintao Xia, Yining Zhao, Chenmei Zhang, Hongqiang Shen   +8 more
wiley   +1 more source

Exploring Potential Mechanism of Quinolone Resistance of Foodborne Listeria monocytogenes Isolates(食品源单增李斯特菌喹诺酮类抗生素耐药机制研究) [PDF]

Shipin kexue jishu xuebao, 2018
The quinolone-resistant isolates were screened from 945 foodborne Listeria monocytogenes, aimed to explore the potential molecular mechanisms of quinolone resistance in Listeria monocytogenes.
CHENG Jianheng(程健恒), CHEN Moutong(陈谋通), CHEN Yuetao(陈月桃), ZHANG Jumei(张菊梅), WU Qingping(吴清平)   +4 more
doaj   +1 more source

The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]

, 2019
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A., D'arpa F., Di Carlo P., Fasciana T., Giammanco A., Gulotta G., Rodolico V., Sergi C., Serra N.   +8 more
core   +1 more source

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga   +4 more
wiley   +1 more source

Mechanism of plasmid-mediated quinolone resistance [PDF]

Proceedings of the National Academy of Sciences, 2002
Quinolones are potent antibacterial agents that specifically target bacterial DNA gyrase and topoisomerase IV. Widespread use of these agents has contributed to the rise of bacterial quinolone resistance. Previous studies have shown that quinolone resistance arises by mutations in chromosomal genes.
John H, Tran, George A, Jacoby
openaire   +2 more sources

Antibiogram and molecular insights into quinolone resistance in Salmonella spp. from food-producing animals in the Philippines

Journal of Infection in Developing Countries
Introduction: The increasing quinolone resistance in food animals in the Philippines has been documented in previous studies. This study aims to investigate the prevalence and underlying molecular mechanisms responsible for quinolone non-susceptibility ...
Lawrence P Belotindos, Angel Mae C Magalong, Marvin Bryan S Salinas, Joel A Miguel Jr., Marvin A Villanueva, Claro N Mingala, Chie Nakajima, Yasuhiko Suzuki   +7 more
doaj   +1 more source

Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence [PDF]

, 2018
Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades and is considered an important driver for the rapid increase of quinolone resistance in E. coli.
A Talaminos, E Torres, JH Han, JR Johnson, L López-Cerero, L López-Cerero, M-H Nicolas-Chanoine, MJ Burgess, P Huizinga, R Banerjee, V Leflon-Guibout   +10 more
core   +1 more source

Successful Use of Bimekizumab in Refractory Acute Generalised Exanthematous Pustulosis Triggered by Amoxicillin‐Clavulanate

JEADV Clinical Practice, EarlyView.
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge, Charlotte Vogel, Theresa Hempel, Basil Signer, Nikhil Yawalkar, Kristine Heidemeyer   +5 more
wiley   +1 more source

First Report of Class 1 and Class 2 Integrons in quinolones resistant Klebsiella pneumoniae isolates from Najaf, Iraq

Инфекция и иммунитет, 2019
Background: Klebsiella pneumoniae is an important opportunistic pathogen associated with nosocomial infections and one of the leading causes of many diseases, and become public health concern especially when characterized as multidrug resistance ...
Samer A. MH Al-Hilali, Taghreed Abdul Kareem AL-Makhzoomy, Hashim Ali Alsherees   +2 more
doaj