Results 71 to 80 of about 3,523,720 (291)
Animal Research and One Health, EarlyView.Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source
Quinolone Resistance Reversion by Targeting the SOS Response
mBio, 2017 Suppression of the SOS response has been postulated as a therapeutic strategy for potentiating antimicrobial agents. We aimed to evaluate the impact of its suppression on reversing resistance using a model of isogenic strains of Escherichia coli ...
E. Recacha +14 more
semanticscholar +1 more source
Mechanisms of quinolone resistance and implications for human and animal health [PDF]
Veterinarski Glasnik, 2010 Quinolone antibiotics have been widely used in human and veterinary medicine. This has caused the development of resistance and difficulties in the treatment of complicated bacterial infections in humans.
Velhner Maja +5 more
doaj +1 more source
Mutations that Separate the Functions of the Proofreading Subunit of the Escherichia coli Replicase
, 2015 The dnaQ gene of Escherichia coli encodes the Ɛ subunit of DNA polymerase III, which provides the 3\u27 - 5\u27 exonuclease proofreading activity of the replicative polymerase.
Kreuzer, Kenneth N., Whatley, Zakiya
core +1 more source
Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms. [PDF]
, 2020 Staphylococcus aureus biofilms are a significant problem in health care settings, partly due to the presence of a nondividing, antibiotic-tolerant subpopulation. Here we evaluated treatment of S.
Allan, RN +7 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Bacterial plasmid-mediated quinolone resistance genes in aquatic environments in China
Scientific Reports, 2017 Emerging antimicrobial resistance is a major threat to human’s health in the 21st century. Understanding and combating this issue requires a full and unbiased assessment of the current status on the prevalence of antimicrobial resistance genes and their ...
Lei Yan +6 more
semanticscholar +1 more source
Consumption of antibiotics at St Luke’s Hospital : a critical factor behind the local prevalence of antimicrobial resistance? [PDF]
, 2006 The intensity of antibiotic use in hospital settings is recognised as possibly the most important factor for the selection of antimicrobial resistance. Hospitals are therefore being encouraged to undertake surveillance and benchmarking of antimicrobial ...
Borg, Michael Angelo, Zarb, Peter
core
Dearomatization with Axial‐to‐Central Chirality Conversion
European Journal of Organic Chemistry, EarlyView.Atropisomers are exciting synthetic targets with unique properties, which find applications in many fields of chemistry. However, considering them as substrates is not very frequent, notably in the context of dearomatization reaction. We wish to discuss the different strategies for the dearomatization of aromatic atropisomers with axial‐to‐central ...
Morgane Mando +3 more
wiley +1 more source
Overview of the development of quinolone resistance in Salmonella species in China, 2005–2016
Infection and Drug Resistance, 2018 Purpose Several factors contribute to the complexity of quinolone resistance in Salmonella, including >2000 different Salmonella serotypes, a variety of hosts for Salmonella, and wide use of quinolones in human beings and animals. We thus aimed to obtain
Qifa Song +3 more
semanticscholar +1 more source