Results 71 to 80 of about 2,195,251 (142)

The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response.

Frontiers in Microbiology, 2015
Quinolone resistance is usually due to mutations in the genes encoding bacterial topoisomerases. However different reports have shown that neither clinical quinolone resistant isolates nor in vitro obtained S.
Alejandra eBernardini, Fernando eCorona, Ricardo eDias, Maria Blanca Sanchez, Jose L Martinez   +4 more
doaj   +1 more source

Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance

Molecules, 2020
Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times. They have enjoyed over 30 years of clinical usage and become essential tools in the armoury of clinical treatments. FQs target the bacterial enzymes DNA gyrase and
Natassja G. Bush, Isabel Diez-Santos, Lauren R. Abbott, Anthony Maxwell   +3 more
doaj   +1 more source

Spatial Patterns and Associated Factors of Intestinal Antibiotic Resistance Genes in Farmed Bullfrogs From Selected Farms Across Major Production Regions in China

Integrative Zoology, EarlyView.
Across selected bullfrog farms in major Chinese production regions, 106 intestinal ARG subtypes were detected, with tetracycline and sulfonamide resistance genes predominating and clear farm‐level variation. High‐risk ARGs, including ermB, floR, and qnrA, were associated with heavy metals, MGEs, and opportunistic pathogens. These findings highlight the
Yang Xu, Rui Chen, Qiang Wei, Zhiming Liu, Jianguo Xiang, Deliang Li, Junhua Li, Xinhua Liu   +7 more
wiley   +1 more source

Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage [PDF]

, 2006
Clerocidin (CL), a diterpenoid natural product, alkylates DNA through its epoxide moiety and exhibits both anticancer and antibacterial activities. We have examined CLaction in the presence of topoisomerase IV from Streptococcus pneumoniae.
Fisher, LM, RICHTER, SARA, Giaretta, G, LEO, ELISABETTA, GIARETTA, GIULIA, Palumbo, M, Leo, E, FISHER L. M, Richter, SN, Gatto, B, GATTO, BARBARA, PALUMBO, MANLIO   +11 more
core   +1 more source

Chlorpromazine inhibits the plasmid-mediated oqxAB multidrug efflux pump in Escherichia coli isolates of Egyptian patients with utis

BMC Microbiology
Over the past ten years, the prevalence of the OqxAB efflux pump, a plasmid-mediated quinolone resistance determinant, has increased among Escherichia coli (E. coli) isolates.
Kholoud Baraka, Rania Abozahra, Fatma Okda, Sarah M. Abdelhamid   +3 more
doaj   +1 more source

Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time‐to‐resolution

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth, Antonio Filipe Macedo, Sofia Somajo, Lukas Tannerfeldt, Baris Toprak, Neil Lagali   +5 more
wiley   +1 more source

Investigation of six plasmid-mediated quinolone resistance genes among clinical isolates of pseudomonas: a genotypic study in Saudi Arabia

, 2019
Mohamed F El-Badawy,1,2 Majed M Alrobaian,3 Mohamed M Shohayeb,1,4 Sayed F Abdelwahab1,51Division of Pharmaceutical Microbiology, Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif 21974, Kingdom of Saudi ...
El-Badawy MF, Abdelwahab SF, Shohayeb MM, Alrobaian MM   +3 more
core  

Inaccuracy of routine susceptibility tests for detection of erythromycin resistance of Campylobacter jejuni and Campylobacter coli [PDF]

, 2009
In The Netherlands, both an increase in and regional differences in erythromycin resistance of Campylobacter jejuni and Campylobacter coli have been reported.
Claas, E.C.J., Dep Infectieziekten Immunologie, Beek, M.T., Advances in Veterinary Medicine, E.J. Kuijper, Mevius, D.J., van der Beek, M., Claas, E.C., Pelt, W., van, Pelt, W. van, E.C.J. Claas, D.J. Mevius, Wagenaar, J.A., van Pelt, W., M.T. van der Beek, Beek, M.T. van der, Kuijper, E.J., van der Beek, M.T., W. van Pelt, J.A. Wagenaar   +19 more
core   +2 more sources

Targeting homologous recombination repair to potentiate fluoroquinolone efficacy in Mycobacterium abscessus

mLife, EarlyView.
Shuai Wang, Md Shah Alam, Buhari Yusuf, Jingran Zhang, Ziwen Lu, Xiaofan Zhang, H. M. Adnan Hameed, Mst. Sumaia Khatun, Chunyu Li, Lijie Li, Aleksey A. Vatlin, Aweke M. Belachew, Xirong Tian, Yamin Gao, Cuiting Fang, Rogers P. Zhang, Jun Li, Xinyue Wang, Liqiang Feng, Li Wan, Tianyu Zhang   +20 more
wiley   +1 more source

Phenotypic Florfenicol Resistance in floR‐Harbouring Flavobacterium psychrophilum Isolates (CC‐ST90): A Case Study From Danish Freshwater Rainbow Trout Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Monitoring antimicrobial resistance (AMR) in fish pathogens is essential for supporting sustainable aquaculture. In this study, susceptibility testing and genome sequencing were used to characterize the AMR profile of seven Flavobacterium psychrophilum originating from Danish rainbow trout farms (2019–2022).
Valentina L. Donati, Lone Madsen
wiley   +1 more source