Results 141 to 150 of about 3,523,720 (291)

Biosynthetically‐Inspired Oxidative Cleavage Platform Enables Rapid Access to Diverse and Architecturally Complex Chemotypes From Indole Alkaloids

ChemistryEurope, Volume 4, Issue 4, April 2026.
We report a biosynthesis‐inspired ring distortion approach that involves oxidative ring cleavage, ring rearrangement, and ring expansion reactions from a diverse collection of indole alkaloids and derivatives. This chemical synthesis approach led to the synthesis of >25 distinct chemotypes from 14 indole alkaloids.
Derek A. Leas, Eli S. Levit, Alexis A. Bragg, Taylor A. Gerrein, Khalil A. Abboud, Pingrong Wei, Lukasz M. Dobrzycki, Robert W. Huigens III   +7 more
wiley   +1 more source

Effect of pH on ciprofloxacin ozonation in hospital WWTP effluent [PDF]

, 2009
A bubble column was used for ozonation of the quinolone antibiotic ciprofloxacin and the effect of pH was tested. Degradation at pH 7 increased the ciprofloxacin half life time to 29.1 min compared to pH 3 (26.8 min) and pH 10 (18.7 min), possibly due to
De Wispelaere, Patrick, De Witte, Bavo, Demeestere, Kristof, Dewulf, Jo, Van Langenhove, Herman   +4 more
core  

Clinical Outcome Associated With Beta‐Lactam Allergy Labels in Hospitalized Patients in Belgium

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Background In the United States, beta‐lactam allergy labels (BLAL) are documented in 9%–16% of hospitalized patients and associated with worse clinical outcomes such as increased mortality, length of hospital stay (LOS), intensive care unit (ICU) admission, and use of alternative antibiotics, providing an incentive for broad delabeling ...
Liesbeth Gilissen, Greet Van De Sijpe, Annouschka Laenen, Peter Declercq, Dries Wets, Ileana Ghiordanescu, Anca Mirela Chiriac, Willy E. Peetermans, Paul De Munter, Isabel Spriet, Rik Schrijvers   +10 more
wiley   +1 more source

Antimicrobial‐Resistance Genetic Markers Among Multidrug‐Resistant Enterobacteriaceae and Acinetobacter spp. From Vegetable Market Chains in Ethiopia

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Schematic overview of the study workflow explaining isolation of lactose‐fermenting Gram‐negative bacteria from farms and supermarkets, antimicrobial susceptibility testing, detection of resistance genes by PCR, and ERIC‐PCR to evaluate genetic diversity and relatedness among isolates.
Hemen Tesfaye, Adey Feleke Desta, Ahu Reis, Mine Egin, Osman Birol Ozgumus, Neslihan Akarsu, Mujib Abdulkadir, Haile Alemayehu, Tadesse Eguale, Ali Osman Kilic   +9 more
wiley   +1 more source

Preclinical efficacy of tasquinimod in myelodysplastic neoplasms: Restoring erythropoiesis and mitigating bone loss

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract Myelodysplastic neoplasms (MDSs) are clonal disorders characterized by ineffective hematopoiesis, dysplasia, and a risk of transformation into acute myeloid leukemia. MDS is also associated with a higher incidence of osteoporosis, suggesting a complex interplay between hematopoiesis, the bone marrow (BM) microenvironment, and bone homeostasis.
Manja Wobus, Heike Weidner, Rebekka Wehner, Anna‐Lena Baumann, Kristin Möbus, Ekaterina Balaian, Marie Törngren, Erik Vahtola, Helena Eriksson, Susann Winter, Uwe Platzbecker, Triantafyllos Chavakis, Lorenz Christian Hofbauer, Martina Rauner, Martin Bornhäuser, Katja Sockel   +15 more
wiley   +1 more source

Investigation of the Frequency of Plasmid-Dependent Quinolone Resistance Genes in Klebsiella Pneumoniae, Pseudomonas Aeruginosa and Escherichia Coli Isolated from Surgical Site Infections

Armaghane Danesh Bimonthly Journal, 2022
Background & aim: In recent years, the rate of antibiotic resistance has been increasing which has led to the limitation of ways to control hospital infections (especially surgical site infections) and accurate treatment options.
M Gholam nezhad, S Hassanzadeh, S Afroughi, S Khorram rouz, E Masnavi, M Shabani   +5 more
doaj  

Isolation of Extracellular Vesicles From Gram‐Negative Bacteria: A Solid Medium‐Based Method Analysis

Journal of Extracellular Biology, Volume 5, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) produced by gram‐negative bacteria have gained increased scientific interest over the last years due to a growing understanding of their roles in pathogenesis and biotechnological potential. However, isolating such nanoparticles is technically challenging. Here, we evaluated a rapid and reproducible protocol for EV
Roberto G. M. Guardatti, Jhonatha R. Cordeiro‐Moura, Jhon J. Artunduaga Bonilla, Stefanie C. da Costa, Anderson S. Cabral, Bruna Montalvão, Flávia G. C. Reis, Leonardo Nimrichter, Márcio L. Rodrigues, Juliana Rizzo, Renata C. Picão   +10 more
wiley   +1 more source

Emerging Antimicrobial Resistance in Klebsiella pneumoniae: A Molecular and Antibiogram Insight From the Beef Value Chain in Bangladesh

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
A total of 132 Multidrug‐resistant Klebsiella pneumoniae was detected across the beef value chain in Bangladesh, including slaughterhouses, wet markets, and ready‐to‐eat beef outlets. Upon cultural traits, PCR, 16S rRNA sequencing, antibiogram analysis, and ARG detection revealed carbapenem resistance genes (blaIMP and blaBIC), highlighting foodborne ...
Md Sodor Uddin, Fahmida Jahan Fahim, Sohel Rana, Abdullah Al Kafi, Jobaida Khanam, Md Nazim Uddin, Md Masudur Rahman, Monira Noor, Md Mukter Hossain, Md Mahfujur Rahman, Md Bashir Uddin, Ferdaus Mohd Altaf Hossain   +11 more
wiley   +1 more source

Nasal Carriage Rate of Biofilm Producing Methicillin Resistant Staphylococcus aureus and Its Associated Factors Among Health Care Workers at Hospital of Central Ethiopia

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
ABSTRACT Not susceptible to methicillin Staphylococcus aureus (MRSA), is a potentially harmful bacteria that is resistant to the most important antimicrobial agents. Because MRSA is so resistant to many antibiotics, it can cause illnesses by forming biofilms.
Wubeshet Mathewos, Abera Kumalo, Takele Teklu, Tigistu Demisse, Muluneh Temesgen, Tariku Chinasho   +5 more
wiley   +1 more source

Increasing trend of multiple resistance and genomic mobility of Neisseria gonorrhoeae to penicillin and quinolone [PDF]

, 2005
A significant decline of gonorrhea incidence has been observed during the years 1990-99. However, a slight increase in the number of cases has been reported in 2000. In addition, an increase in resistant strains has been found in Thailand. In this study,
Buatiang, Anukul, Jittawoutipoka, Thichakorn, Lawung, Ratana, Prachayasittikul, Virapong, Rittiroongrad, Surawach   +4 more
core