Results 1 to 10 of about 44,560 (245)

Biological Effects of Quinolones: A Family of Broad-Spectrum Antimicrobial Agents

open access: yesMolecules, 2021
Broad antibacterial spectrum, high oral bioavailability and excellent tissue penetration combined with safety and few, yet rare, unwanted effects, have made the quinolones class of antimicrobials one of the most used in inpatients and outpatients ...
Ana R. Millanao   +4 more
doaj   +1 more source

Plasmid-mediated quinolone resistance genes transfer among enteric bacteria isolated from human and animal sources

open access: yesAIMS Microbiology, 2021
This research investigates the transferability of plasmid-mediated quinolone resistance (PMQR) genes among enteric bacteria isolates in human and animal samples, as well as its implication on resistance of recipient cells.
EHWARIEME Daniel Ayobola   +2 more
doaj   +1 more source

Repeated Exposure of Escherichia coli to High Ciprofloxacin Concentrations Selects gyrB Mutants That Show Fluoroquinolone-Specific Hyperpersistence

open access: yesFrontiers in Microbiology, 2022
Recent studies have shown that not only resistance, but also tolerance/persistence levels can evolve rapidly in bacteria exposed to repeated antibiotic treatments.
Aurore Perault   +5 more
doaj   +1 more source

Rapid Limit Test of Eight Quinolone Residues in Food Based on TLC-SERS, a New Limit Test Method

open access: yesMolecules, 2023
Residual quinolones in food that exceed their maximum residue limit (MRL) are harmful to human health. However, the existing methods used for testing these residues have limitations; so, we developed a new limit test method called TLC-SERS to rapidly ...
Honglian Zhang   +8 more
doaj   +1 more source

Antimicrobial Resistance in Escherichia coli Isolated from Healthy Dogs and Cats in South Korea, 2020–2022

open access: yesAntibiotics, 2023
The occurrence of antimicrobial-resistant bacteria in companion animals poses public health hazards globally. This study aimed to evaluate the antimicrobial resistance profiles and patterns of commensal E.
Bo-Youn Moon   +9 more
doaj   +1 more source

Synthesis and “In Silico” Evaluation of the Biological Activity of the New Dual Inhibitors of Gyrase DNA and Topoisomerase IV

open access: yesProceedings, 2020
Quinolones are effective against a broad range of bacterial species and provide potent treatmentoptions for a few infections [1,2]. [...] 
Lucia Pintilie   +3 more
doaj   +1 more source

Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin

open access: yesYankuang ceshi, 2021
BACKGROUND At present, the supervision of antibiotic abuse and its research is being strengthened. In recent years, antibiotics have been detected in varying degrees in water in central China.
MA Jian-sheng   +4 more
doaj   +1 more source

The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria

open access: yesFrontiers in Pharmacology, 2022
The emergence of Plasmodium falciparum (Pf) parasite strains tolerant of the artemisinin component and resistant to the other drug component in artemisinin combination therapies (ACTs) used for treatment now markedly complicates malaria control.
Daniel J. Watson   +5 more
doaj   +1 more source

Genomic Characteristics of Colistin-Resistant Salmonella enterica subsp. enterica Serovar Infantis from Poultry Farms in the Republic of Serbia

open access: yesAntibiotics, 2020
The antimicrobial susceptibility testing was conducted on 174 single isolates from poultry farms in Serbia and it was determined that seven Salmonella spp. were multidrug resistant.
Branko Jovčić   +9 more
doaj   +1 more source

Matrix effects and compensation measures of quinolones detection in animal derived food by HPLC-MS/MS

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveTo study the matrix effects (MEs) and the compensation measures of 15 quinolones (QNs) determination in animal derived food by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) .MethodsFish, pork and chicken as typical
LI Daoxia   +5 more
doaj   +1 more source

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