Results 21 to 30 of about 143,165 (330)

The Synthesis of Diquinone and Dihydroquinone Derivatives of Calix[4]arene and Electrochemical Characterization on Au(111) surface.

open access: yesActa Chimica Slovenica, 2016
Several new electroactive diquinone and dihydroquinone derivatives of calix[4]arene bearing anchor functional groups were designed, synthesized and characterized. A method for selective protection of the hydroquinone –OH groups with trimethylsilyl groups
Bostjan Genorio
doaj   +1 more source

Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction

open access: yesPharmaceuticals, 2022
Plastoquinone analogs are privileged structures among the known antiproliferative natural product-based compound families. Exploiting one of these analogs as a lead structure, we report the investigation of the brominated PQ analogs (BrPQ) in ...
Ayse Tarbin Jannuzzi   +9 more
doaj   +1 more source

Microsomal superoxide anion production and NADPH-oxidation in a series of 22 aziridinylbenzoquinones [PDF]

open access: yes, 1989
Several 2,5-bis(1-aziridinyl)-1,4-benzoquinones (BABQs) can be activated to alkylating species by reduction of the quinone moiety. On the other hand, cytotoxicity of these compounds can be induced by redox cycling.
Koster, Andries Sj.   +3 more
core   +3 more sources

The Candida albicans ζ-crystallin homolog Zta1 promotes resistance to oxidative stress

open access: yesmSphere, 2023
The fungal pathogen Candida albicans is capable of causing lethal infections in humans. Its pathogenic potential is due in part to the ability to resist various stress conditions in the host, including oxidative stress.
Rafael M. Gandra   +3 more
doaj   +1 more source

Characterization of a Reductively-Activated Elimination Pathway Relevant to the Biological Chemistry of the Kinamycins and Lomaiviticins [PDF]

open access: yes, 2012
The lomaiviticins (1 and 2) and kinamycins (3–5) are bacterial metabolites with potent antimicrobial and antiproliferative activities. Herein we establish that 1–5 are capable of generating electrophilic acylfulvene intermediates (6) under mildly ...
Ding, Weidong   +4 more
core   +3 more sources

A novel quinone: Quinone methide isomerase generates quinone methides in insect cuticle

open access: yesFEBS Letters, 1988
Insoluble cuticle‐bound enzyme(s) of Manduca sexta pharate pupae, which is known to convert N‐acetyldopamine to N‐acetylnorepinephrine through the intermediate formation of quinone methide, also converted exogenously supplied N‐acetyldopamine quinone to N‐acetylnorepinephrine.
Steven J. Saul, Manickam Sugumaran
openaire   +3 more sources

Computational studies on electronic and optical properties of dopamine derivatives structure: A DFT study**

open access: yesJournal of the Mechanical Behavior of Materials, 2021
Dopamine is considered an important molecule that plays several essential roles in the human body, and herein lies the key to this paper on the electronic and optical properties of dopamine and its derivatives, such as quinone and L ...
Jabbar Mohammed L.
doaj   +1 more source

High-Throughput Virtual Screening of Quinones for Aqueous Redox Flow Batteries: Status and Perspectives

open access: yesBatteries, 2022
Quinones are one of the most promising and widely investigated classes of redox active materials for organic aqueous redox flow batteries. However, quinone-based flow batteries still lack the necessary performance in terms of metrics, such as specific ...
Abhishek Khetan
doaj   +1 more source

Electrochemistry of potentially bioreductive alkylating quinones : Part 1. Electrochemical properties of relatively simple quinones, as model compounds of mitomycin- and aziridinylquinone-type antitumour agents [PDF]

open access: yes, 1990
The influence of methyl-, hydroxy and amino substituents on the electrochemical behaviour of simple 1,4-naphtho-and 1,4-benzoquinones, model compounds of many quinoid antitumour agents, in aqueous media was studied. Significant changes in electrochemical
Bos, M.   +9 more
core   +2 more sources

Convenient Synthesis of 2-Thioimidazolone/Menadione Conjugates via a Two-Step Sequence Starting with Direct Amination of Menadione

open access: yesSynOpen, 2020
A convenient route to conjugates of 2-thiohydantoins and menadione with linkers of various chemical nature through a two-stage reaction sequence (direct amination of the menadione with a functional amine followed by modification of a functional group) is
Dmitry A. Guk   +3 more
doaj   +1 more source

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