Results 61 to 70 of about 66,627 (253)

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

The kinetics of the reduction of the lipophilic quinone avarone by n-alkyl-1,4-dihydronicotinamides of various lipophilicities

Journal of the Serbian Chemical Society, 1999
Several NADH model compounds, N-alkyl-1,4-dihydronicotinamides, some of them possessing amphiphilic properties, have been synthesized, and the kinetics of their reaction with a biologically active liphophilic quinone, avarone, has been studied in a ...
MIROSLAV J. GASIC, DUSAN SLADIC, MARIO ZLATOVIC   +2 more
doaj  

Simultaneous Wastewater‐to‐Hydrogen Upgrading via Mechanically Driven Piezocatalysis Over Ag‐ZnO Nanorods

Advanced Science, EarlyView.
A piezocatalytic strategy enables simultaneous wastewater purification and hydrogen generation by harnessing mechanical energy. Complementary piezo‐induced charges are selectively directed toward oxidation and reduction pathways, achieving efficient pollutant degradation and continuous H2 evolution.
Yiqing Wei, Jianghai Huang, Yejunchi Zhang, Yang Wang, Dongmei Li, Chaogang Ban, Peng Yu, Jiangping Ma, Zhenxiang Cheng   +8 more
wiley   +1 more source

Spatially Separated Redox Centers in One‐Dimensional Sp2‐Carbon Covalent Organic Frameworks Enable Synergistic Photocatalytic Palladium Recovery and Bisphenol A Mineralization

Advanced Science, EarlyView.
A one‐dimensional sp2‐carbon covalent organic framework with spatially segregated redox centers integrates a dual photosensitizing system and a cationic interface for synergistic photocatalysis. The material achieves exceptional palladium recovery (1749 mg g−1) and bisphenol A mineralization (0.1710 min−1) without sacrificial agents, demonstrating ...
Yi‐Ru Chen, Jing‐Yi Li, Yao Xiao, Dan Zhong, Lu Zhang, Yu‐Ting Xie, Xiu Wang, Yibao Li, Wei‐Rong Cui, Jian‐Ding Qiu   +9 more
wiley   +1 more source

Haustorium Inducing Factors for Parasitic Orobanchaceae

Frontiers in Plant Science, 2019
Parasitic plants in the Orobanchaceae family include devastating weed species, such as Striga, Orobanche, and Phelipanche, which infest important crops and cause economic losses of over a billion US dollars worldwide, yet the molecular and cellular ...
Vincent Goyet, Syogo Wada, Songkui Cui, Takanori Wakatake, Ken Shirasu, Ken Shirasu, Gregory Montiel, Philippe Simier, Satoko Yoshida, Satoko Yoshida   +9 more
doaj   +1 more source

Carboxyphenolate Coordination Frameworks for High‐Voltage Calcium Storage

Advanced Science, EarlyView.
A hexaanionic carboxyphenolate coordination framework, Ca2‐M‐THBPD (M = Mg, Ca, Ba), exhibits ligand‐centered enolate‐quinonoid redox activity enabling tunable, high‐voltage Ca2+ storage (3.5 V vs Ca2+/Ca) modulated by spectator cations. The amorphous structure accommodates reversible divalent‐ion insertion, contributing to enhanced cycling stability ...
Vasudeva Rao Bakuru, Darsi Rambabu, Xiaodong Lin, Robert Markowski, Petru Apostol, Viliam Frano, Xiaolong Guo, Taniya Purkait, Shubhadeep Pal, Tom Goossens, Da Tie, Augustin Ramackers, Alexandru Vlad   +12 more
wiley   +1 more source

SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2020
This study is aimed at evaluating the impact of N- and S- bonding modes of thiocyanate substituent on catecholase activity as its presence in the coordination sphere of the metal complex can either reduce catecholase activity or otherwise. 4-Methyl-2-(
AYOWOLE O. AYENI, GARETH M. WATKINS 1
doaj  

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

Advanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang, Ziqi Wang, Ye Weng, Yulin Fu, Yuelong Jiang, Beilin Zhuang, Wenzi Zeng, Xiangchun Zhang, Bing Xu, Jie Zha, Hongjun Zhuang   +10 more
wiley   +1 more source

The dominant component of strong π-hole interactions: electrostatic attraction versus charge transfer

IUCrJ, 2023
Aleksander Shkurenko
doaj   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source