Results 121 to 130 of about 14,380 (267)

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Polyphenylquinoxalines via Aromatic Nucleophilic Displacement [PDF]

Polyphenylquinoxalines are produced by an aromatic nucleophilic displacement reaction involving an activated aromatic dihalide with an appropriate quinoxaline monomer. Polyphenylquinoxalines are high temperature thermoplastics used as adhesives, coatings,
Connell, John W., Hergenrother, Paul M.
core   +1 more source

Транспортные свойства ионообменных мембран в растворах нитрата аммония [PDF]

, 2008
З метою вивчення можливості застосування електродіалізу для знесолення стічних вод, що містять з'єднання аміаку вивчена електрохімічна поведінка гетерогенних іонообмінних мембран МК-40 і МА-40 у розчинах нітрату й хлориду й амонію.
Медянцева, Д. Г., Шишкина, С. В.   +1 more
core  

Hybrid Diagonal Approximation in Time‐Dependent Auxiliary Density Functional Theory

Journal of Computational Chemistry, Volume 46, Issue 23, September 5, 2025.
Our work demonstrates that time‐dependent auxiliary density functional theory (TD‐ADFT) in combination with the hybrid diagonal approximation (HDA) for global and range‐separated hybrid functionals is a promising approach for low‐order scaling electronic excitation energy calculations.
Kevin O. Pérez‐Becerra, Jesús N. Pedroza‐Montero, Mark R. Pederson, Luis I. Hernández‐Segura, Andreas M. Köster   +4 more
wiley   +1 more source

Quinoxaline 1,4-di-N-oxide and the Potential for Treating Tuberculosis [PDF]

, 2011
New drugs active against drug-resistant tuberculosis are urgently needed to extend the range of TB treatment options to cover drug resistant infections.
Aldana, I. (Ignacio), Ancizu, S. (Saioa), Burguete, A. (Asunción), Goldman, R.C. (Robert C.), Jaso, A. (Andrés), Marin, A. (Adoración), Monge, A. (Antonio), Pérez-Silanes, S. (Silvia), Solano, B. (Beatriz), Vicente, E. (Esther), Villar, R. (Raquel), Zarranz, B. (Belén)   +11 more
core  

Связывание катионов триоксадихиноксалина-дииндолизиноциклопентадекафаном и его ациклическим аналогом [PDF]

, 2008
Методом циклической вольтамперометрии исследовано связывание ионов Li⁺, Na⁺, K⁺, Cs⁺, Ag⁺, Zn²⁺, Ni²⁺, Co²⁺ (I группа), H⁺, Mg²⁺, Al³⁺, Ga³⁺ (II группа), Ca²⁺, Pb²⁺ (III группа) 2¹,3¹-дифенил-1²,4²-диоксо-7,10,13-триокса-1,4 (3,1)-дихиноксалина-2 (2,3)
Калинин, А. А., Мамедов, В. А., Настапова, Н. В., Степанов, А. С., Янилкин, В. В.   +4 more
core  

Oxidant-free annulation of α-hydroxy ketones with diamines using aluminum(III) chloride: A supramolecular approach for practical quinoxaline synthesis

Results in Chemistry
The conventional reaction of α-hydroxy ketones (acyloins) with arene-1,2-diamines typically requires an oxidant to facilitate a tandem oxidative condensation, resulting in quinoxaline derivatives. In this study, an innovative approach has been introduced
Maryam Farajpour Mojdehi, Hani Sayahi, Saeed K. Amini, Farshid Mohsenzadeh, Hossein Reza Darabi, Kioumars Aghapoor   +5 more
doaj   +1 more source

Synthesis of some new quinoxalines with expected pharmacological activities [PDF]

4-Methylphenylenediamine 1 was reacted with α-dicarbonylsto give quinoxalines 2a-g, 4a-d and/or 7a-c.Quinoxalines 7a-c were converted into dihydropyridazinoquinoxalines 9a-c, thienoquinoxalines 10a-c and/or dichloroquinoxalines 11a-c.
Assy, M.G., Khalil, A., Sherif, M.H., Zahran, F.   +3 more
core  

Antimicrobial activity of quinoxaline 1,4-dioxide and three derivatives [PDF]

, 2014
O presente trabalho descreve o estudo da actividad e antimicrobiana de quarto derivados da quinoxalina N,N-dióxido: quinoxalina 1,4-dióxido, 2-metilquinoxalina 1,4- dióxido, 6-cloro-2,3-dimetilquinoxalina 1,4-dióxido e 3-benzoil-2-metilquinoxalina 1,4-
Fernandes, Rúben, Noronha, João Paulo, Prudêncio, Cristina, Silva, M., Vieira, Mónica   +4 more
core  

Quinoxaline Derivatives. V. Some Reactions of 2-Cyano-3-hydroxyquinoxaline 1-Oxide [PDF]

, 1965
Yusuf Ahmad, Muhammad Salman Habib, M. Zubair Iqbal, Ziauddin Ziauddin   +3 more
openalex   +1 more source