Results 71 to 80 of about 14,696 (253)

Gold-catalyzed oxidation of arylallenes: Synthesis of quinoxalines and benzimidazoles

Beilstein Journal of Organic Chemistry, 2011
A gold-catalyzed oxidation of arylallenes to form α-diketones and aldehydes in good yields is presented. Further directed synthesis of quinoxalines and benzimidazoles, via the condensation of the resulting α-diketones and aldehydes with benzene-1,2 ...
Dong-Mei Cui, Dan-Wen Zhuang, Ying Chen, Chen Zhang   +3 more
doaj   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

New opportunities for the synthesis of quinoxaline derivatives

Chimica Techno Acta, 2019
Convenient methods for the synthesis of quinoxaline derivatives with the use of nucleophilic aromatic substitution of hydrogen in heteroaromatic part of molecule in conditions of the acid catalysis were elaborated.
Olga S. Koptyaeva, Yuriy A. Azev, Yuriy M. Shafran, Tatyana A. Pospelova, Oleg N. Chupakhin   +4 more
doaj   +1 more source

Asymmetric Catalytic Hydrogenation toward a Value‐Added Chiral Building Block: Optically Active γ‐Butyrolactone Scaffold from Renewable and Synthetic Derived Feedstocks

European Journal of Organic Chemistry, Volume 29, Issue 3, January 22, 2026.
This brief compendium summarizes the most successful asymmetric hydrogenation strategies for the preparation of chiral monocyclic γ‐lactone derivatives from keto acids and keto esters, with emphasis on their relevance for large‐scale production and high enatioselectivities. This article provides a brief compendium on the production of chiral monocyclic
Marta Feliz, Maria J. Sabater
wiley   +1 more source

Taming hazardous chemistry in flow: The continuous processing of diazo and diazonium compounds [PDF]

, 2014
The synthetic utilities of the diazo and diazonium groups are matched only by their reputation for explosive decomposition. Continuous processing technology offers new opportunities to make and use these versatile intermediates at a range of scales with ...
Collins, Stuart G., Deadman, Benjamin J., Maguire, Anita R.   +2 more
core   +1 more source

Total Synthesis of the Cyanobacterial Alkaloid Nostodione A

European Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.
The total synthesis of the alkaloid nostodione A is successfully achieved utilizing 3,4‐dihydrocyclopenta[b]indole‐1,2‐dione as a key intermediate. The sensitive benzylidene moiety is introduced via a Knoevenagel condensation with p‐hydroxybenzaldehyde.
Oscar F. Casadiego‐Díaz, Ángel Rentería‐Gómez, Teresa Ramírez‐Apan, Rubén O. Torres‐Ochoa   +3 more
wiley   +1 more source

Ultra‐Sensitive Short‐Wave Infrared Organic Photodetectors Enabled by a π‐Conjugation Extended Proquinoid Electron Acceptor

Advanced Functional Materials, Volume 36, Issue 5, 15 January 2026.
A novel proquinoid‐type electron acceptor, TQC‐4Cl, with an ultra‐narrow bandgap of 1.01 eV and spectral response beyond 1200 nm enables organic SWIR photodetectors. The optimized devices show a high EQE of 13.66% and high specific detectivity over 1012 Jones at 1200 nm under −0.5 V reverse bias with outstanding thermal stability, highlighting their ...
Yeonsu Choi, Se Jeong Park, Seunghyun Oh, Un‐Hak Lee, Seunghyun Rhee, Dong Ryeol Whang, Sein Chung, Juhyoung Jung, Kilwon Cho, Bo Ram Lee, Sung Cheol Yoon, Jae Won Shim, Seo‐Jin Ko   +12 more
wiley   +1 more source

2,3-Bis(4-bromophenyl)quinoxaline [PDF]

Acta Crystallographica Section E Structure Reports Online, 2007
The title compound, C(20)H(12)Br(2)N(2), was prepared by the reaction of 1-(3-bromo-phen-yl)-2-(4-bromo-phen-yl)ethane-1,2-dione with o-phenyl-enediamine in refluxing ethanol. In the mol-ecule, all bond lengths and angles are within normal ranges. The dihedral angle between the two benzene rings is 34.89 (1)°.
Fang-Fang Jian, Ke-Fei Wang, Rui-Rui Zhuang, Hai-Lian Xiao   +3 more
openaire   +3 more sources

Large-Scale Solvent-Free Chlorination of Hydroxy-Pyrimidines, -Pyridines, -Pyrazines and -Amides Using Equimolar POCl3

Molecules, 2012
Chlorination with equimolar POCl3 can be efficiently achieved not only for hydroxypyrimidines, but also for many other substrates such as 2-hydroxy-pyridines, -quinoxalines, or even -amides.
Zhihua Sun, Yongjia Shen, Ye Xiang, Han Wang, Kun Wen, Le Wang, Xiaocheng Xu   +6 more
doaj   +1 more source

Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides. [PDF]

, 2017
A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl ...
Gu, Yang, Gu, Yucheng, Lu, Changhui, Shen, Qilong, Wu, Jiang   +4 more
core   +1 more source