Results 81 to 90 of about 26,379 (326)

Synthetic strategies for 5- and 6-membered ring azaheterocycles facilitated by iminyl radicals [PDF]

open access: yes, 2016
The author thanks EaStCHEM for financial support.The totality of chemical space is so immense that only a small fraction can ever be explored. Computational searching has indicated that bioactivity is associated with a comparatively small number of ring ...
Walton, John Christopher
core   +2 more sources

Computer-guided design of novel nitrogen-based heterocyclic sphingosine-1-phosphate (S1P) activators as osteoanabolic agents

open access: yesEXCLI Journal : Experimental and Clinical Sciences
Osteoanabolic agents, or drugs that promote bone formation, have gained considerable attention for osteoporosis management due to their curative and preventive potentials.
Rattanawan Tangporncharoen   +5 more
doaj   +1 more source

Advances in Ligand‐Driven Pd‐Catalyzed C─H Functionalizations: Recent Insights and Updates

open access: yesChemCatChem, EarlyView.
The most significant advances in ligand‐driven Pd‐catalyzed organic synthesis over the past two years are presented. Processes involving C─H activation of substrates, avoiding their prefunctionalization are illustrated. Both the activity and selectivity of the catalyst depend on the design of the ligands (pyridones, pyridines, amino acids, phosphines ...
Jesús Moradell   +3 more
wiley   +1 more source

The path of least resistance: Paying for antibiotics in non-human uses [PDF]

open access: yes, 2014
Antibiotic resistance is a critical threat to human and animal health. Despite the importance of antibiotics, regulators continue to allow antibiotics to be used in low-value applications - subtherapeutic dosing in animals, and spraying tobacco plants ...
Aidan Hollis   +48 more
core   +1 more source

Thioxanthone: A Benchmark Photocatalyst for Organic Synthesis

open access: yesChemCatChem, EarlyView.
Thioxanthone is a highly versatile and effective organocatalyst for photochemical applications, with its low‐toxicity, metal‐free structure driving growing interest in sustainable photocatalysis. Building on our previous 2021 review, this update covers advances from 2021–2025 in thioxanthone‐based synthetic organic photochemistry – excluding ...
Vera P. Demertzidou   +2 more
wiley   +1 more source

Radical Fluoroalkylation Reactions [PDF]

open access: yes, 2018
Recent protocols and reactions for catalytic radical perfluoroalkylations will be described. The production of perfluoroalkyl radicals (RF = CnF2n+1, n ≥ 2), which effect both addition and substitution reactions on organic substrates, can be realized ...
Barata Vallejo, Sebastian   +2 more
core   +1 more source

Large-Scale Solvent-Free Chlorination of Hydroxy-Pyrimidines, -Pyridines, -Pyrazines and -Amides Using Equimolar POCl3

open access: yesMolecules, 2012
Chlorination with equimolar POCl3 can be efficiently achieved not only for hydroxypyrimidines, but also for many other substrates such as 2-hydroxy-pyridines, -quinoxalines, or even -amides.
Zhihua Sun   +6 more
doaj   +1 more source

Polycyclic Aromatics as Promising Phosphorescence Materials

open access: yesChemistryEurope, EarlyView.
This review focuses on the recent progress of polycyclic aromatic compounds (PACs)‐based phosphorescent materials. Their molecular structural characteristics as promising phosphors are highlighted, and the efficient strategies from molecular and aggregation levels have been illustrated systematically to promote the development of PACs with desirable ...
Peipei Liu, Qianqian Li, Zhen Li
wiley   +1 more source

Exploring the Impact of Phenanthroline‐Based Glycoconjugated Ru(II) Polypyridyl Photosensitizers on Metastasis‐Related Processes

open access: yesChemistry – A European Journal, EarlyView.
A novel family of water‐soluble, nontoxic, and phosphorescent N‐glycosylated Ru(II) phenanthroline‐based complexes are reported. They exhibit photoselectivity indexes ranging from 10 to 44 in PC‐3 cells, while impacting cell migration and resistance to detachment after irradiation with blue light.
Elena de la Torre‐Rubio   +5 more
wiley   +1 more source

Gold-catalyzed oxidation of arylallenes: Synthesis of quinoxalines and benzimidazoles

open access: yesBeilstein Journal of Organic Chemistry, 2011
A gold-catalyzed oxidation of arylallenes to form α-diketones and aldehydes in good yields is presented. Further directed synthesis of quinoxalines and benzimidazoles, via the condensation of the resulting α-diketones and aldehydes with benzene-1,2 ...
Dong-Mei Cui   +3 more
doaj   +1 more source

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