Results 81 to 90 of about 14,380 (267)

The LANCA three-component reaction to highly substituted β-ketoenamides – versatile intermediates for the synthesis of functionalized pyridine, pyrimidine, oxazole and quinoxaline derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2019
The LANCA three-component reaction of lithiated alkoxyallenes LA, nitriles N and carboxylic acids CA leads to β-ketoenamides KE in good to excellent yields.
Tilman Lechel   +4 more
doaj   +1 more source

Polyphenylquinoxalines via aromatic nucleophilic displacement [PDF]

open access: yes, 1990
Polyphenylquinoxalines are prepared by the nucleophilic displacement reaction of di(hydroxyphenyl)quinoxaline monomers with activated aromatic dihalides or dinitro compounds.
Connell, John W., Hergenrother, Paul M.
core   +2 more sources

Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides. [PDF]

open access: yes, 2017
A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl ...
Gu, Yang   +4 more
core   +1 more source

Polycyclic Aromatics as Promising Phosphorescence Materials

open access: yesChemistryEurope, EarlyView.
This review focuses on the recent progress of polycyclic aromatic compounds (PACs)‐based phosphorescent materials. Their molecular structural characteristics as promising phosphors are highlighted, and the efficient strategies from molecular and aggregation levels have been illustrated systematically to promote the development of PACs with desirable ...
Peipei Liu, Qianqian Li, Zhen Li
wiley   +1 more source

Efficient and Practical Protocol for the Synthesis of Pyridopyrazines, Pyrazines and Quinoxalines Catalyzed by La(OAc)3 in Water [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2013
La(OAc)3 has been used as an efficient catalytic system for the synthesis of quinoxalines. This method provides several advantages over methods that are currently employed such as a simple work-up, mild reaction conditions, good to excellent yields, and ...
Ghasem Rezanejade Baradajee   +1 more
doaj  

Asymmetric Synthesis and Biological Evaluation of 1,3‐ and 1,4‐Disubstituted Isoquinoline‐Containing Lipoxin A4 Analogues

open access: yesChemistry – A European Journal, EarlyView.
(1R)‐ and (1S)‐Epimers of novel isoquinoline‐derived SPMs were prepared, with a Pd‐catalyzed Heck reaction and a Ru(II)‐catalyzed asymmetric transfer hydrogenation as the key synthetic steps. Biological assessment demonstrated that several analogues significantly attenuate lipopolysaccharide‐induced NF‐κB activation and downstream pro‐inflammatory ...
Denise Moran   +4 more
wiley   +1 more source

Phospho Sulfonic Acid Catalyzed Synthesis of Benzimidazole, Benzoxazole and Quinoxaline Derivatives under Green Solvent at Ambient Temperature [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2016
Phospho sulfonic acid (PSA) synthesized as an environmentally safe and efficient solid acid catalyst, and it used for the synthesis of several 2-disubstituted benzimidazoles, 2-substituted benzoxazoles, and 2-substituted quinoxalines in ethanol as a ...
S. Rezayati   +5 more
doaj  

Electron Transfer-oxy Radical Mechanism for Anti-cancer Agents: 9-anilinoacridines [PDF]

open access: yes, 1987
A possible mode of action involving electron transfer is advanced for the 9- anilinoacridines. The mechanism entails formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R.   +2 more
core   +1 more source

Electronic effects in the cyclocondensation of benzil [PDF]

open access: yes, 2010
Electronic effects are important directing forces in the course of chem. reactions. Small differences in these effects can bring about considerable changes in the results of very similar reactions.
Nagendrappa, G.
core   +1 more source

Nickel‐Catalyzed P‐Arylation of HP(= O)(R/OR)2 Nucleophiles with (Hetero)Aryl Chlorides Enabled by DalPhos Ligation

open access: yesChemistry – A European Journal, EarlyView.
The development of broadly useful C‐P cross‐couplings of (hetero)aryl chlorides and HP(O)(R/OR)2 nucleophiles by use of nickel/DalPhos‐based catalysts is described, along with findings from DFT studies that confirm the preference for C‐P bond formation in this system arising from three‐cantered reductive elimination through substrate PV pathways ...
Michael J. Cotnam   +5 more
wiley   +1 more source

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