Results 81 to 90 of about 826 (192)

Innovation models and technological parks: interaction between parks and innovation agents

Journal of Technology Management & Innovation, 2018
Technological parks are strategic innovation places for the stimulation of synergy among different agents. Current theoretical study identifies forms of interactions between technological parks and agents mentioned in interactive models of innovation ...
Hilka Vier Machado, Fábio Lazzarotti, Fernando Fantoni Bencke   +2 more
doaj   +1 more source

Circular entrepreneurial ecosystems: a Quintuple Helix Model approach

Management Decision
PurposeThe shift toward a circular economy (CE) represents a collaborative endeavor necessitating the presence of efficient frameworks, conducive contexts and a common comprehension. This research serves as a pivotal stride towards this goal, presenting an exclusive prospect for the investigation and fusion of these frameworks, with particular emphasis
Juan D. Borrero, Shumaila Yousafzai
openaire   +2 more sources

Improving Proteolysis‐Targeting Chimera Delivery by Targeting Key Biomarkers in Tumor Endocytosis Pathways

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen, Jiayan Jiao, Huiling Yang, Tao He   +3 more
wiley   +1 more source

Genetic dissection of southern corn leaf blight resistance in sweet corn through genome‐wide association studies and genomic selection

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Southern corn leaf blight (SCLB) is caused by the fungal pathogen Bipolaris maydis (syn. Cochliobolus heterostrophus Drechsler) and is a common disease of fall crops of sweet corn. Phenotyping for SCLB resistance is performed through visual scoring, which is subjective and may limit genetic gain for this quantitative trait.
Darlon V. Lantican, Juan M. Gonzalez, Marco Antonio Peixoto, Kristen A. Leach, Larissa Carvalho Ferreira, Vitor A. Silva de Moura, Katia V. Xavier, Peter Balint‐Kurti, William Tracy, Marcio F. R. Resende Jr.   +9 more
wiley   +1 more source

Nutritional quality traits in pea seed: Current knowledge and opportunities for genetic improvement

Annals of Applied Biology, Volume 189, Issue 2, September 2026.
This comprehensive review on nutritional traits in pea (Pisum sativum L.) summarizes the literature on genetic improvement of this highly nutritious and environmentally sustainable crop for different end‐uses. Abstract Pea is a major pulse crop valued for its high protein, carbohydrate, and mineral content, as well as its agronomic role in sustainable ...
Ahmed O. Warsame, Janneke Balk
wiley   +1 more source

Prospective evaluation of the Simple Fetal Medicine Foundation's first‐trimester prediction model for preeclampsia in twin pregnancies

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1707-1716, September 2026.
The Simple Fetal Medicine Foundation model effectively predicts preeclampsia (PE) in twin pregnancies at 11 +0–13 + 6 weeks using only maternal risk factors and mean arterial pressure. It achieves a high detection rate for early onset PE (area under the receiver operating characteristic curve 0.911 for PE <30 weeks) and provides a simple, convenient ...
Cuilian Liu, Jiaxin Li, Yang Chen, Tianchen Wu, Qingnan Meng, Kuo Zhang, Yuan Wei   +6 more
wiley   +1 more source

Exploration of Nirmatrelvir Derivatives as Optimized SARS‐CoV‐2 Antivirals

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Structure‐guided optimization of nirmatrelvir identifies aldehyde and dichloroacetamide warheads and a potency‐enhancing S4 thioamide. Crystal structures reveal an S2 rearrangement extending toward Cys44, suggesting a new covalent‐design opportunity.
Yugendar R. Alugubelli, Veerabhadra R. Vulupala, Kai S. Yang, Kaustav Khatua, Lauren R. Blankenship, Sathish Kumar, Demonta Coleman, Xuejiao Guo, Zhi Zachery Geng, Chia‐Chuan D. Cho, Banumathi Sankaran, Benjamin W. Neuman, Shiqing Xu, Wenshe Ray Liu   +13 more
wiley   +1 more source

Operationalizing human–AI collaboration in city intelligence systems

Discover Cities
Cities face compounding shocks, however, many “smart city” initiatives stall because data and pilots do not translate into enforceable, revisable governance. This research conceptualizes City Intelligence Systems (CIS) as an ecosystem governance capacity
Xiuli Chen, Joohan Ryoo
doaj   +1 more source

CLUSTERS IN INNOVATION: TRIPLE HELIX, QUADRUPLE HELIX AND QUINTUPLE HELIX MODELS

Odessa National University Herald. Economy, 2020
Olena Reshetnyak, Roman Lobodin
openaire   +1 more source

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, Volume 32, Issue 30, 13 August 2026.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source