Durable formulations of quorum quenching enzymes [PDF]
Scientific ReportsEnzymes with industrial potential often face limitations due to stability and longevity constraints. Thermostable quorum quenching lactonases are appealing biotechnology tools for controlling microbial pathogenicity and biofilm formation via the ...
Reed Jacobson +2 more
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Quorum Sensing and Quorum Quenching with a Focus on Cariogenic and Periodontopathic Oral Biofilms [PDF]
Microorganisms, 2022 Numerous in vitro studies highlight the role of quorum sensing in the pathogenicity and virulence of biofilms. This narrative review discusses general principles in quorum sensing, including Gram-positive and Gram-negative models and the influence of ...
Patricia P. Wright +1 more
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Quorum Quenching Approaches against Bacterial-Biofilm-Induced Antibiotic Resistance [PDF]
AntibioticsWith the widespread phenomenon of antibiotic resistance and the diffusion of multiple drug-resistant bacterial strains, enormous efforts are being conducted to identify suitable alternative agents against pathogenic microorganisms.
Patrizia D’Aquila +6 more
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Critical Assessment of the Prospects of Quorum-Quenching Therapy for Staphylococcus aureus Infection. [PDF]
Int J Mol Sci, 2023 Staphylococcus aureus is an important pathogen that causes a high number of infections and is one of the leading causes of death in hospitalized patients. Widespread antibiotic resistance such as in methicillin-resistant S.
Otto M.
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A Novel and Efficient Platform for Discovering Noncanonical Quorum-Quenching Proteins [PDF]
Microbiology Spectrum, 2023 Quorum sensing (QS) is a well-known chemical signaling system responsible for intercellular communication that is widespread in bacteria. Acyl-homoserine lactone (AHL) is the most-studied QS signal.
Jinxing Liao +7 more
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The quorum quenching enzyme Aii20J modifies in vitro periodontal biofilm formation. [PDF]
Front Cell Infect Microbiol, 2023 Introduction Recent studies have revealed the presence of N-acyl-homoserine lactones (AHLs) quorum sensing (QS) signals in the oral environment. Yet, their role in oral biofilm development remains scarcely investigated.
Parga A +9 more
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Innovative microbial disease biocontrol strategies mediated by quorum quenching and their multifaceted applications: A review. [PDF]
Front Plant Sci, 2022 With the increasing resistance exhibited by undesirable bacteria to traditional antibiotics, the need to discover alternative (or, at least, supplementary) treatments to combat chemically resistant bacteria is becoming urgent.
Zhu X +8 more
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Catalytic Redundancies and Conformational Plasticity Drives Selectivity and Promiscuity in Quorum Quenching Lactonases. [PDF]
JACS AuSeveral enzymes from the metallo-β-lactamase-like family of lactonases (MLLs) degrade N-acyl L-homoserine lactones (AHLs). They play a role in a microbial communication system known as quorum sensing, which contributes to pathogenicity and biofilm ...
Corbella M +8 more
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Quorum quenching effect of cyclodextrins on the pyocyanin and pyoverdine production of Pseudomonas aeruginosa. [PDF]
Appl Microbiol BiotechnolVarious virulence determinants in Pseudomonas aeruginosa are regulated by the quorum sensing (QS) network producing and releasing signalling molecules.
Fekete-Kertész I +5 more
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Potential of the quorum-quenching and plant-growth promoting halotolerant Bacillus toyonensis AA1EC1 as biocontrol agent. [PDF]
Microb BiotechnolThe use of fertilizers and pesticides to control plant diseases is widespread in intensive farming causing adverse effects together with the development of antimicrobial resistance pathogens.
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