Results 41 to 50 of about 7,972 (218)

Evolution of the Quorum network and the mobilome (plasmids and bacteriophages) in clinical strains of Acinetobacter baumannii during a decade [PDF]

open access: yes, 2018
In this study, we compared eighteen clinical strains of A. baumannii belonging to the ST-2 clone and isolated from patients in the same intensive care unit (ICU) in 2000 (9 strains referred to ...
Blasco, Lucía   +11 more
core   +2 more sources

A Rhodococcal Transcriptional Regulatory Mechanism Detects the Common Lactone Ring of AHL Quorum-Sensing Signals and Triggers the Quorum-Quenching Response

open access: yesFrontiers in Microbiology, 2018
The biocontrol agent Rhodococcus erythropolis disrupts virulence of plant and human Gram-negative pathogens by catabolizing their N-acyl-homoserine lactones.
Corinne Barbey   +25 more
doaj   +1 more source

Crystal Structures of a Quorum-quenching Antibody [PDF]

open access: yesJournal of Molecular Biology, 2007
A large number of Gram-negative bacteria employ N-acyl homoserine lactones (AHLs) as signaling molecules in quorum sensing, which is a population density-dependent mechanism to coordinate gene expression. Antibody RS2-1G9 was elicited against a lactam mimetic of the N-acyl homoserine lactone and represents the only reported monoclonal antibody that ...
Erik W, Debler   +5 more
openaire   +2 more sources

Quorum quenching quandary: resistance to antivirulence compounds [PDF]

open access: yesThe ISME Journal, 2011
Abstract Quorum sensing (QS) is the regulation of gene expression in response to the concentration of small signal molecules, and its inactivation has been suggested to have great potential to attenuate microbial virulence. It is assumed that unlike antimicrobials, inhibition of QS should cause less Darwinian selection pressure for ...
Toshinari, Maeda   +6 more
openaire   +2 more sources

Screening of N-Acyl Homoserine Lactone-degrading Bacteria and Evaluation of Their Quorum Quenching Activities

open access: yesShipin gongye ke-ji
To study the types of quorum quenching bacteria in soil and their quorum quenching characteristics, the study screened, isolated, and identified quorum quenching strains from soil and assessed their quorum quenching properties, the inhibitory and ...
Xiqian TAN   +6 more
doaj   +1 more source

Signal Disruption Leads to Changes in Bacterial Community Population

open access: yesFrontiers in Microbiology, 2019
The disruption of bacterial signaling (quorum quenching) has been proven to be an innovative approach to influence the behavior of bacteria. In particular, lactonase enzymes that are capable of hydrolyzing the N-acyl homoserine lactone (AHL) molecules ...
Michael Schwab   +15 more
doaj   +1 more source

Breaking down bacterial communication: a review of quorum quenching agents

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background Bacterial cells communicate via small extracellular molecules that facilitate gene expression which is dependent on cell density and this mechanism is known as Quorum Sensing (QS).
Tresa Boban, Sahaya Nadar, Savita Tauro
doaj   +1 more source

Quorum Quenching in Culturable Phyllosphere Bacteria from Tobacco [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
Many Gram-negative plant pathogenic bacteria employ a N-acylhomoserine lactone (AHL)-based quorum sensing (QS) system to regulate their virulence traits. A sustainable biocontrol strategy has been developed using quorum quenching (QQ) bacteria to interfere with QS and protect plants from pathogens. Here, the prevalence and the diversity of QQ strains
Ma, Anzhou   +3 more
openaire   +2 more sources

Identification of QuiP, the Product of Gene PA1032, as the Second Acyl-Homoserine Lactone Acylase of Pseudomonas aeruginosa PAO1 [PDF]

open access: yes, 2006
The relevance of the acyl homoserine lactone (acyl-HSL) quorum signals N-3-oxododecanoyl-homoserine lactone (3OC12HSL) and N-butanoyl-homoserine lactone to the biology and virulence of Pseudomonas aeruginosa is well investigated.
Huang, Jean J.   +3 more
core   +1 more source

Rhodotorula Mucilaginosa, a Quorum Quenching Yeast Exhibiting Lactonase Activity Isolated from a Tropical Shoreline

open access: yesSensors, 2014
Two microbial isolates from a Malaysian shoreline were found to be capable of degrading N-acylhomoserine lactones. Both Matrix Assisted Laser Desorption Ionization-Time of Flight-Mass Spectrometry and 18S rDNA phylogenetic analyses confirmed that these ...
Norshazliza Ab Ghani   +5 more
doaj   +1 more source

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