Results 71 to 80 of about 152,081 (201)

Oral microbiome and homeostatic regulation of periodontal health: From dysbiosis to precision intervention

open access: yesVIEW, EarlyView.
Periodontal homeostasis is maintained by coordinated interactions between the oral microbiome and host. Dysbiosis disrupts this ecological balance and contributes to periodontal disease, whereas multi‐omics, artificial intelligence, and microbiome‐based interventions provide emerging opportunities for precision diagnosis, ecological restoration, and ...
Xu Liu   +11 more
wiley   +1 more source

Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties

open access: yesScientific Reports, 2018
Quorum quenching lactonases are enzymes that are capable of disrupting bacterial signaling based on acyl homoserine lactones (AHL) via their enzymatic degradation.
Celine Bergonzi   +5 more
doaj   +1 more source

Quorum Quenching of Nitrobacter winogradskyi Suggests that Quorum Sensing Regulates Fluxes of Nitrogen Oxide(s) during Nitrification

open access: yesmBio, 2016
Quorum sensing (QS) is a widespread process in bacteria used to coordinate gene expression with cell density, diffusion dynamics, and spatial distribution through the production of diffusible chemical signals.
Brett L. Mellbye   +3 more
doaj   +1 more source

A live‐cell autophagy reporter reveals reversible vacuolation in naked mole‐rat skin fibroblasts under lysosomal stress

open access: yesThe FEBS Journal, EarlyView.
A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong   +6 more
wiley   +1 more source

Drugs for the Quorum Sensing Inhibition of Oral Biofilm: New Frontiers and Insights in the Treatment of Periodontitis

open access: yesPharmaceutics, 2022
Chemical molecules are used by microorganisms to communicate with each other. Quorum sensing is the mechanism through which microorganisms regulate their population density and activity with chemical signaling.
Alessandro Polizzi   +5 more
doaj   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor   +4 more
wiley   +1 more source

A Genetic Circuit System Based on Quorum Sensing Signaling for Directed Evolution of Quorum-Quenching Enzymes

open access: yes, 2010
Quorum sensing is a cell cell communication mechanism that is involved in the regulation of biological functions such as luminescence, virulence, and biofilm formation.
Hak-Sung Kim   +7 more
core   +1 more source

Dicarboxymethyl Cellulose‐Based Mixed‐Matrix Membrane Adsorbers: Preparation, Characterization, and Protein Retention Performance

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 47, December 15, 2026.
Dicarboxymethyl cellulose is incorporated, for the first time, into a polyethersulfone membrane. The functional membranes are prepared using dimethyl isosorbide through combined non‐solvent and vapor‐induced phase separation. The resulting membranes exhibit porous structures and protein‐retention potential, highlighting the potential of this cellulose ...
Diana Gago   +7 more
wiley   +1 more source

Engineering better quorum quenching enzymes [PDF]

open access: yes, 2017
Many clinically relevant bacterial pathogens (e.g. Pseudomonas aeruginosa) use chemical signals to communicate with one another as a precursor to initiating infection and/or biofilm formation (a process called quorum sensing).
James Wiggins, Thomas   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy