Quorum Quenching Agents: Resources for Antivirulence Therapy [PDF]
Marine Drugs, 2014 The continuing emergence of antibiotic-resistant pathogens is a concern to human health and highlights the urgent need for the development of alternative therapeutic strategies.
Kaihao Tang, Xiao-Hua Zhang
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Quorum sensing and self-quorum quenching in the intracellular pathogen Brucellamelitensis. [PDF]
PLoS ONE, 2013 Brucella quorum sensing has been described as an important regulatory system controlling crucial virulence determinants such as the VirB type IV secretion system and the flagellar genes.
Matthieu Terwagne +5 more
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Novel T4ASS effector with quorum quenching activity. [PDF]
ISME J, 2023 Venturi V, Bez C.
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Majalah Kedokteran Andalas, 2020 Background: Quorum-sensing is communication between bacterial involved in virulence. Bacterial virulence can be inhibited by quorum-quenching mechanism. Endophytic bacteria of pegagan leaf may produce secondary metabolit similar to bioactive compounds in
Nur Al Huda +4 more
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Resistance to Quorum-Quenching Compounds [PDF]
Applied and Environmental Microbiology, 2013 ABSTRACT Bacteria have the remarkable ability to communicate as a group in what has become known as quorum sensing (QS), and this trait has been associated with important bacterial phenotypes, such as virulence and biofilm formation. Bacteria also have an incredible ability to evolve resistance to all known antimicrobials.
Rodolfo, García-Contreras +2 more
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Quorum Sensing Interfering Strategies and Their Implications in the Management of Biofilm-Associated Bacterial Infections [PDF]
Brazilian Archives of Biology and Technology, 2020 The bacterial species employ various types of molecular communication systems recognized as quorum sensing for the synchronization of differential gene expression to regulate virulence traits and biofilm formation. A variety of quorum sensing inhibitors;
Samman Munir +8 more
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A new class of quorum quenching molecules from Staphylococcus species affects communication and growth of gram-negative bacteria. [PDF]
PLoS Pathogens, 2013 The knowledge that many pathogens rely on cell-to-cell communication mechanisms known as quorum sensing, opens a new disease control strategy: quorum quenching.
Ya-Yun Chu +6 more
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Heliyon, 2021 Andrographis paniculata (Burm f.) Nees is a tropical plant native to Southeast Asia that has been used as an effective remedy for a wide variety of illnesses in traditional Chinese and Ayurvedic medicine.
An Margarete Tan Lim +5 more
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Quorum Quenching Revisited—From Signal Decays to Signalling Confusion
Sensors, 2012 In a polymicrobial community, while some bacteria are communicating with neighboring cells (quorum sensing), others are interrupting the communication (quorum quenching), thus creating a constant arms race between intercellular communication. In the past
Kok-Gan Chan +4 more
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Quorum-quenching activity of the AHL-lactonase from Bacillus licheniformis DAHB1 inhibits vibrio biofilm formation in vitro and reduces shrimp intestinal colonisation and mortality [PDF]
, 2014 Vibrio parahaemolyticus is a significant cause of gastroenteritis resulting from the consumption of undercooked sea foods and often cause significant infections in shrimp aquaculture. Vibrio virulence is associated with biofilm formation and is regulated
Shanthi, S. +4 more
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